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Tue, 15 Jul 2003 15:44:22 -0500

HSI - Jenny Thompson

Hot Potato

 

Hot Potato

 

The Health Sciences Institute e-Alert

 

July 15, 2003

 

************************************************************

 

Dear Member,

 

What are we doing to our kids?

 

That's the unspoken question that runs through an e-mail I received last week

from an HSI member named Carrie who began by saying: " URGENT suggestion: Why

don't you write about the drug Risperdal? "

 

Carrie did some research on her own, so she was able to make a wise decision

about Risperdal. In other words, she didn't have to learn the hard way what a

dangerous drug this is. Unfortunately, many parents who trust their

pediatricians' judgment may be in for a shock. But just as unfortunate are the

elderly Alzheimer's patients who are also given Risperdal - with sometimes grave

consequences.

 

----------------------------

Drug abuse

----------------------------

 

Risperdal (the brand name for risperidone) is the most frequently prescribed

antipsychotic medication in the U.S. The FDA has approved Risperdal for the

treatment of schizophrenia, but it is not approved for children. Of course, that

doesn't prohibit doctors from prescribing the drug for a child - even if the

young patient has been diagnosed with a condition far less severe than

schizophrenia.

 

Here's Carrie's experience, in her own words: " Doctors are giving Risperdal to

children in droves. However, I called the drug company up and they do not

recommend it for kids, nor has it been approved by the FDA for children.

 

" A doctor prescribed it for my son who is 8. I dropped the doctor like a hot

potato. They are using Risperdal on children with ADHD to help control them. It

can cause incurable disease in children and it is causing strokes and killing

the elderly. I talked with a lawyer and was told some parents are giving it to

their children who are only 2 and 3 years old. "

 

If you're a longtime HSI member and regular e-Alert reader, then you're probably

not wondering how a large group of doctors - independent of one another - would

decide to prescribe a potent schizophrenia drug to young children. They do it

because salespeople for the drug company encourage them to prescribe " outside

the box. " Meanwhile, the manufacturer's customer service representatives are

telling people on the phone that the drug is not recommended for kids.

 

Great system: Give the " insider " spin to doctors to pump up sales; give the

politically correct spin to consumers; everybody wins. Except the kids.

 

----------------------------

Into the unknown...again

----------------------------

 

Risperdal is manufactured by a division of Johnson & Johnson, called Jannsen

Pharmaceuticals. Approved by the FDA almost 10 years ago, Risperdal was known at

the outset to cause a number of possible side effects, including anxiety,

dizziness, nausea, rapid heartbeat, and sleepiness. Some Risperdal users feel

lightheaded when they stand up too quickly. And in a few cases, patients

experienced tremors, and even uncontrollable facial twitches.

 

In recent years, however, this list of side effects has come to include

irregular blood pressure, irregular heartbeat, and muscle rigidity. These

problems have led to 37 confirmed reports of stroke in elderly patients,

resulting in 16 deaths.

 

If these numbers were attached to ephedra instead of Risperdal, the mainstream

press would be howling for a ban. Instead, last April Johnson & Johnson quietly

distributed letters to U.S. doctors, warning that Risperdal raises the risk of

stroke among seniors.

 

What permanent damage this drug may be doing to kids, however, is pure

speculation, because no studies have been conducted to determine the effects of

Risperdal in very young subjects. And it's doubtful that such studies could ever

take place. Imagine how unethical it would be to test a psychotropic drug on

children and infants. There's no telling what permanent damage such a potent

drug would have on developing brains.

 

And yet doctors and psychiatrists are conducting that very test every day by

prescribing Risperdal to young people who are diagnosed with " conduct

disorders. "

 

I think Carrie has the right idea: these doctors should be dropped like hot

potatoes.

 

----------------------------

Skin deep

----------------------------

 

One of the most unfortunate aspects of Alzheimer's is when patients develop

" conduct disorders. " Needless to say, these patients are sometimes inclined to

forget or even reject their medication. But Johnson & Johnson has a plan to take

care of that problem.

 

Two years ago Johnson & Johnson acquired Alza Corporation - one of the first

developers of sustained-release medications. Alza invented " the patch " for

smokers. This is Alza's specialty: devising new ways to conveniently deliver

drugs. A recent Alza innovation is a device called Duros - a rod about the size

of a one inch pencil lead - that is implanted just under the skin where it

releases small amounts of a drug for up to one year.

 

Risperdal is one of the J & J drugs that are currently being developed for

application with Duros. But if a Risperdal Duros reaches the market, you can bet

it won't be cheap. As it is, Risperdal costs more than $7 per day. When the new

delivery device is added, you have to imagine that the cost will go up, and

Jannsen salespeople will, in turn, step up their sales efforts to make the new

generation of Risperdal a success.

 

Suddenly the idea of kids being over-prescribed psychotropic drugs seems almost

tame compared to the idea of Risperdal or Ritalin implants.

 

No wonder Johnson & Johnson executives spent more than $13 billion to purchase

Alza. They saw the future of medication - and its name is " Convenience. "

 

----------------------------

Ka-boom

----------------------------

 

The information package that comes with Risperdal warns that once a patient is

feeling better they must continue to take their dosage to prevent symptoms from

returning. So what does this mean for a patient who's 3 or 6 or 10? Are they

embarking on a lifetime commitment to a medication that they'll never remember

not having?

 

Earlier this year a study in the Archives of Pediatrics and Adolescent Medicine

reported that the use of psychotropic drugs by children in the U.S. more than

doubled during the 1990s, and has almost matched adult usage of the same drugs.

 

That's not growth - that's explosion.

 

In her e-mail, Carrie made this closing request: " Please advise parents to

search the web for every drug their children are prescribed so they can make

safe choices for them. " If every parent were as diligent in avoiding potent,

untested drugs as Carrie has been, we could all feel much better about the

health of our children. And this is another place the HSI network can work so

well. If you know someone with young children - or aging parents - please

forward this e-mail to them. The risks of Risperdal are too great to not spread

the word.

 

Share this HSI e-Alert with a friend

 

Carrie didn't mention what sort of alternative to Risperdal she finally settled

on for her son. But if you have a child or grandchild who has had one of these

drugs recommended to address disorderly conduct or ADHD, I urge you to read the

e-Alert " How To Dismantle An '89 Ford " (6/2/02), in which HSI Panelist Allan

Spreen, M.D., outlines a nutritional regimen that might make all the difference

between a child with a clear mind and a child with a mind clouded by

pharmaceuticals.

 

************************************************************

(if you can't click here use the HTML links listed below)

 

************************************************************

 

...and another thing

 

What's the difference between powder and soda? Just one little word.

 

In the e-Alert " McMedicine " (6/25/03) I told your how the average person my

absorb anywhere from 10 to 100 mg of aluminum every day through aluminum

deodorants, cookware, baking soda, antacids, and other sources. This is a

concern, of course, because aluminum toxicity has been associated with

Alzheimer's disease.

 

But it appears that I had one little (but important) word wrong.

 

An HSI member named Pati wrote with this question:

 

" My family and I have been using baking soda as a deodorant for several years

now, so that we could avoid the aluminum in regular deodorants. We have found it

to be better than most health store varieties and have really liked it, but it

looked - from your recent article - that it too contains aluminum. Is this

correct? If so, then ANY type of deodorant - even in the health stores - that

claims to be free of aluminum but that also has baking soda listed is also to be

avoided. Is this so? "

 

Good catch, Pati. This question was also brought up on the HSI Forum in a thread

titled " Baking Soda & Alzheimer's Disease. " It's gratifying to know that

everyone is paying such close attention!

 

In a nutshell, here's the lowdown: Baking soda doesn't contain aluminum, but

baking POWDER does (unless you go out of your way to find aluminum-free baking

powder). So if you're getting good results from a deodorant that contains baking

soda - fear not - your product is aluminum-free. (By the way, I should have

caught that one myself as my toothpaste is also baking soda based. Shame on me.)

 

To Your Good Health,

 

Jenny Thompson

Health Sciences Institute

 

************************************************************

Sources:

" About Risperdal " Risperdal web site, risperdal.com

" Risperdal Children " A Drug Recall.com, adrugrecall.com

" Psychotropic Practice Patterns for Youth " Archives of Pediatrics and Adolescent

Medicine, Vol. 157, No. 1, January 2003, archpedi.ama-assn.org

" A Long Way from Tiny Time Pills " Philip Siekman, Fortune, 7/7/03, fortune.com

" Company to Warn of Possible Risperdal Stroke Risk " Reuters Health, 4/11/03,

reuters.com

 

Copyright ©1997-2003 by http://www.hsibaltimore.com, L.L.C. The e-Alert may

not be posted on commercial sites without written permission.

 

************************************************************ Before you hit

reply to send us a question or request, please click here

http://www.hsibaltimore.com/ealert/questions.shtml

 

************************************************************

If you'd like to participate in the HSI Forum, search past e-Alerts and products

or you're an HSI member and would like to search past articles, visit

http://www.hsibaltimore.com

 

************************************************************

To learn more about the Health Sciences Institute, call (508) 368-7494 or

http://www.agora-inc.com/reports/HSI/WHSIC313.

 

************************************************************

 

 

 

 

 

 

 

 

@

 

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To , e-mail to:

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Or, go to our group site at:

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