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**Note I do not own this company and have nothing to with them..Just use

their products in my clinics, and believe them to be some of the best on

the market.

 

UniBone™: An Ayurvedic Formulation Backed By Research

 

March 2003

 

As an ingredient supplier of Ayurvedic botanicals, Geni Herbs

understands the need to have valid scientific data available for both

product development and benefit validation. The company is therefore

working closely with a network of universities to conduct several

clinical studies on its products. In addition, Pharmanza, its

manufacturing division, works with the Indian forestry department and

harvesters to set strict guidelines and specifications. Additional

standards are used to test all raw materials, assuring standardization

of the active compounds with the materials.

One Ayurvedic product undergoing such scrutiny is the company's UniBone,

a joint health formulation to help facilitate fracture healing. Bone is

a dynamic tissue with equilibrium between bone deposition and

resorption. When bone fractures occur, the healing time is typically 6

to 20 weeks, depending on the type of fracture. The stages of natural

bone repair are inflammation, soft callus formation, hard callus

formation, and remodeling. With the aid of ancient Ayurvedic formulas

and modern science, UniBone has been proven effective in promoting

faster healing.

 

FRACTURE FACTS

 

According to the National Osteoporosis Foundation, one in two women and

one in four men over age 50 will have an osteoporosis-related fracture,

accounting for more than 1.5 million fractures annually. National costs

associated with these fractures in 2001 were $47 million per day! A

recent study found that children aged 10 to 14 years also had very high

fracture rates. The study also showed that each year, approximately 1 in

37 boys and 1 in 62 girls, 10 to 14 years of age, will require

orthopedic services for a fractured bone (HPN Online, Jan. 5, 2002).

 

WHY AYURVEDA?

 

A variety of products - from vitamins to hormones such as thyroxin,

estrogen, growth hormone, and androgenic hormones - have been used to

hasten the process of bone healing in fractures, but unfortunately with

little success. Hence, the search continues to find an alternative from

any healthcare practice that will benefit fracture patients in terms of

reducing their morbidity, decreasing the period of immobilization and

suffering, hastening the recovery process, and return to normal health.

Fortunately, an Ayurvedic herb has revealed a possible solution.

 

INTRODUCING CISSUS QUADRANGULARIS

 

The company's interest in this herb was aroused when it came to know the

Sanskrit name for Cissus quadrangularis - " Hadjod, " which literally

means " bone-union. " This name was undoubtedly coined after its efficacy

in the skeletal system was established. Its first reference is found in

Bhavna Chikitsa, an Ayurvedic text written by the physician Chakradata

in the 11th century.

 

The recommended dosage is three to five grams of powder, or 600 to 1,000

mg of extract in divided doses per day. Phytochemically, 100 grams of

this fresh plant contain 267 mg of carotene and 398 mg of vitamin C. It

also contains steroidal principle, which has been found to be helpful in

the fracture-healing process.

However, in order for ancient Ayurvedic formulas to gain scientific

validity in today's world, extensive clinical trials must be conducted.

Although Geni Herbs' search for more information on Cissus

quadrangularis uncovered promising data from animal studies, there was

only scarce information from human studies, despite the fact that this

herb had been used for centuries. Thus began the company's own crusade

to examine this ingredient more closely.

 

UNIBONE STUDIES

An open pilot study was conducted using the company's UniBone extract,

which contained Cissus quadrangularis manufactured and supplied by

Pharmanza India. The extract was administered in capsule form three

times a day to patients with long fractures in their legs that had been

fixed with an interlocking nail. The average fracture healing time for

these patients (with long-bone fractures), normally 16 to 20 weeks, was

reduced to 12 to 14 weeks in the UniBone-treated group, a result that

was confirmed radiographically. Among the volunteers who participated in

this study were two postgraduate doctors who provided ideal clinical

feedback about the product. Additionally, no side effects were reported.

 

This reduction in healing time motivated Geni Herbs to explore the

clinical efficacy of UniBone even further. The company believes that

such results were sufficient enough for UniBone to be studied further

for its role in facilitating the healing of bone fractures. Based on

research to date, Geni Herbs recommends a dosage of UniBone at 500 mg in

capsule form three times a day.

 

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Geni Herbs is the exclusive distributor of UniBone, available in powder,

liquid, and granular extracts. The company also offers bulk tablets and

capsules for private label needs. For more information on UniBone or

Cissus quadrangularis, call (317) 776-3600.

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