Guest guest Posted March 7, 2003 Report Share Posted March 7, 2003 http://www.integrativephysician.org/NutritionResearch.htm Research, Public Policy and Practice - Never the 'Twain Shall Meet By Catherine Creel 2001 Catherine Creel, . Email: ccreel How a Myth is Born During the mid-1970's, the USDA published its first edition of " Using the Dietary Guidelines for Americans " . The most startling recommendation it contained was that Americans should reduce their overall fat intake to no more than thirty percent of their daily calories, with only ten percent of these calories coming from saturated fat. The dietary recommendations in this publication were premature. For several years preceding the release of this report, scientists and doctors had argued that the evidence to support lowering daily allowances of fat was hardly conclusive. In fact, the National Academy of Sciences (NAS), in charge of setting RDAs (Recommended Dietary Allowances) and the AMA (American Medical Association) had voiced concerns that a decreased intake of dietary fat would lead to health problems. Under pressure to produce some health guidelines, the USDA ignored these doubts and forged ahead. In a bold move, the NAS released its own report which did not support a lower fat diet. The USDA worked to discredit the NAS report by revealing that the NAS received some financial support from the food industry. This story came to national attention when Jane Brody wrote about it in the New York Times. Due to this connection, the media and the people were suspicious of NAS's motives and quickly embraced the recommendations of the USDA. Science, finding itself in the awkward and uncomfortable position of having no data to support the new dietary guidelines began scrambling to provide supportive evidence. Attempting to accomplish this, the National Institute of Health (NIH) funded several studies over a ten year period aimed at scientifically proving the dangers of saturated fat. The results of these studies not only failed to even remotely suggest that lowering dietary fat would lead to better health, they actually suggested otherwise. Finally, a study was done on a group of men whose cholesterol levels exceeded those of ninety-five percent of Americans. This group was placed on cholesterol-reducing medication. The study, done by Lipid Research Clinic (LRC) was known as the Coronary Primary Prevention Trial. After seven years, it showed that those taking the drug experienced a 0.4% reduction in probability of having a heart attack over the placebo group. This same reduction applied to the probability of dying from a heart attack. Surprisingly, dietary data was not part of this study. LRC falsely extrapolated that these findings could be replicated by reducing fat intake, leading to lower levels of blood cholesterol, and resulting in a decrease in heart disease. Although other scientists argued that the study could hardly support the dietary hypothesis of a lower fat diet, the NIH made official the flawed conclusions of the Coronary Primary Prevention Trial. The next day, headlines throughout the country shouted that we were a nation doomed to die unless we turned to the low fat diet of the USDA. Our Health Today Now in the new millennium, we look at our health statistics in America. Type II diabetes is of epidemic proportions, affecting younger as well as older adults. Hypertension (high blood pressure) affects over twenty-five percent of Americans over the age of eighteen. While statistics on heart disease show a modest decrease in death due to heart disease in our society, a closer look reveals millions more people being treated for heart disease than ever before. It remains the number one cause of death in America today. It is not unusual today for elementary school teachers to have twenty percent or more of their students diagnosed as having Attention Deficit and Hyperactivity Disorder and being treated with pharmaceutical drugs that have toxic side effects. Millions of people are being pharmaceutically treated for depression, including teenagers and children. We have large numbers of people being given the relatively new, catch-all diagnosis of Chronic Fatigue Syndrome. Finally, obesity in the U.S. is at an all-time high, despite our consumption of fat being at an all-time low (34% of our overall calories per day). Deconstructing the Myth A look at health statistics from other countries reveals the startling evidence that some cultures have much lower rates of these diseases than people in the U.S., make fewer visits to medical professionals, and take few to no pharmaceutical drugs. Three things are immediately apparent when looking at their diets: 1) Only whole foods are eaten 2) The fat content of the diets is 40% or higher 3) More fatty fishes and seafood are included in their diets We've known about the diets of these cultures for some time, but until recent years, lacked the necessary knowledge to truly understand why and how these diets work to keep them healthy. We are now able to comprehend the reasons behind the success of these diets through our increased understanding of fatty acids and our ability to create fatty acid profiles. Through fatty acid profiling, we learned that people of these cultures have very different ratios of the essential fatty acids, omega-6 and omega-3, from the ratios of people in cultures like the U.S. who have high rates of the diseases mentioned earlier. The diets of the cultures that enjoy better health, contain ratios of omega-6 fatty acids to omega-3 fatty acids in the range of 4:1 to 1:1. The culture having the 1:1 ratio was the healthiest of all. This is in great contrast to the standard American diet (with the very appropriate acronym of SAD) which has ratios of omega-6 fatty acids to omega-3 fatty acids of 15:1 to 20:1 or more. Now, we have over two thousand studies that confirm that diets with fatty acid ratios of 4:1 to 1:1 (omega-6's to omega-3's) lead to better overall health. Understanding Essential Fatty Acids Omega-6 and omega-3 fatty acids are essential to life and must be obtained through our diets. Omega-6 fatty acids include Linoleic acid (LA), and Gamma-linoleic acid (GLA). Omega-3 fatty acids include Alpha-linolenic acid (LNA), Eicosapentaenoic acid (EPA), Docosapentaenoic acid (DPA), and Docosahexaenoic acid (DHA). An overabundance of omega-6 fatty acids is found in the human-made category of fats referred to as trans-fatty acids (or trans-fat), most grains, and animal fat from grain-fed animals. Trans-fats appeared after food manufacturers jumped on the USDA recommendation for a diet lower in saturated fat and began to make vegetable oils from by-products of the cotton and animal feed industries. These oils were highly unstable and prone to oxidation. This made them fairly useless in food products. Through a process known as hydrogenation, this " problem " was corrected. These inexpensive hydrogenated and partially hydrogenated oils were used to make margarines, as additives in packaged foods, and in virtually all commercially baked items. It is nearly impossible to buy a packaged item today that doesn't contain some partially hydrogenated vegetable oils. These oils can also be found in some reduced fat milks containing the ingredient called dry milk solids. They lower HDL (good cholesterol) and raise LDL (bad cholesterol) while causing damage to the body through encouraging free radical formation. The ratios of omega-6's to omega-3's in these hydrogenated and partially hydrogenated oils run from a low of 20:1 to over 70:1! The low fat movement has added to the damaging effects of these oils by encouraging people to eat less of the oils and foods that contain more fat. We now know that these oils and foods contain fewer omega-6's while providing more of the protective omega-3's. Omega-3 fatty acids are found in preferable ratios to omega-6 fatty acids in fresh vegetables, fatty fish, most lean cuts of meat and skinless poultry, especially in animals that eat grass and vegetation (true free range), including game animals. Aged cheeses, especially those made from raw milk also provide a reasonable balance of omega-6’s to omega-3’s. Milk is a much more controversial food now implicated in many diseases that plague modern times. This is a complex topic that is best served by an in-depth article. Briefly (and incompletely) summarized, some of the things we know about milk are that homogenization destroys the structural integrity of the proteins in dairy products, making them impossible to assimilate, and pasteurization also affects the nutritional integrity of milk. Milk that is commercially produced comes from source animals that are grain-fed. This has negative effects the fatty acid profile of milk. RBGH is a growth hormone given to cows to produce more milk. They have been repeatedly linked to reduced insulin sensitivity in children and adults. Current research into milk has discovered a health-enhancing fatty acid called Conjugated Linoleic acid (CLA), found consistently in pasture-fed cows of certain breeds, and inconsistently and at unpredictable levels in some breeds of grain-fed dairy cows. We need to understand this more fully in order to take milk off the list of harmful foods. Some Quick Facts On Essential Fatty Acids (obtained from scientific studies) * Omega-3 fatty acids block the growth of malignant tumors. Omega-6 fatty acids promote the growth of malignant tumors. * Omega-3 fatty acids help to prevent cardiac arrhythmias, protect arteries by reducing levels of homocysteine and blocking inflammation, help prevent blood clots, normalize blood pressure, inhibit build up of plaque, and raises HDL (good cholesterol) while maintaining or reducing LDL (bad cholesterol). Omega-6 fatty acids have the opposite effects. * Omega-3 fatty acids increase insulin sensitivity. Omega-6 fatty acids decrease insulin sensitivity. * The DHA in omega-3 fatty acids promotes emotional well-being. A high ratio of omega-6 fatty acids to omega-3's produces depression, irritability, psychosis, ADHD, violent and impulsive behavior, and increases cravings for addictive substances. By increasing omega-3's and decreasing omega-6's, these symptoms are reduced or eliminated. * Increasing omega-3's while decreasing omega-6's has positive effects on autoimmune and inflammatory diseases. Healthy Eating You can begin putting this knowledge can be put into action by following the general guidelines below. Oils - Extra virgin cold-pressed olive oil (rich in squalene which reduces LDL twenty percent or more), unprocessed canola oil, high-oleic sunflower and high-oleic safflower oils are safest. Complex carbohydrates - vegetables, vegetables, vegetables - at least six servings a day. Your body will tell you which ones are right for you. If you are carbohydrate-sensitive (insulin resistant) you may find that vegetables grown underground (called tubers) don't agree with you. If at all possible, buy organic. You avoid a lot of pesticides this way and also get the benefits of more concentrated vitamins and minerals. Green vegetables, rich in antioxidants, are great. One of my favorites, collard greens, is well-known in the South and just beginning to get a little exposure in the Northeast. They take a little longer to cook than most greens. I steam them for 12-15 minutes. As a rule, the darker the green, the richer it is in antioxidants, vitamins, and minerals. Steer clear of corn. Fruit - this is another category where you must pay attention to what your body tells you. For people who are carbohydrate sensitive, berries and cantaloupe work best (I find that I can now eat most fruits as my insulin response has improved due to my diet). Eat at least three servings a day. Be aware that most fruits have been genetically manipulated to be sweeter than they originally were. I buy organic Heirloom varieties from natural food stores in my area. I enjoy that these stores are quite willing to order things I want, and get answers to my questions about the origins of their products. When buying fruit juices make sure they contain the pulp. This makes them digestible and creates less of a spike in insulin response. Breads and Grains - Eat whole grain bread that is sourdough only, and in moderation. The sourdough seems to neutralize the effects of the omega-6's here. Be aware that most grains are overprocessed, taking away components that are necessary for balance and assimilation. People with autoimmune and inflammatory disorders usually find inprovement in their health when they eliminate grain-based products. Most grains contain very high ratios of omega-6's to omega-3's. The grains containing the lowest ratios are hard winter wheat and wheat germ at about 10:1 omega-6's to omega-3's. Oatmeal, as unprocessed as you can get it is occasionally acceptable due to having some positive effects on health. Stay away from overprocessed white flour products, and minimize your grains unless they are hand-milled. Protein - Eat lean cuts of meat cooked at 350 degrees or below. Exclude pork. If possible, eat grass-fed beef and true free-range skinless poultry. Animals that are fed few to no grains resulting in very low in omega-6 fatty acids. Eat fatty fish at least three times a week (swordfish, Alaskan salmon, mackerel, anchovy, sardine, etc.). Avoid farm-raised fish. They produce so little omega-3's naturally that they are fed fish oil supplements. They are also fed grains. This is a very unnatural food for fish. Despite its reputation, seafood is full of healthy fat in the form of omega-3's. When choosing lamb, remember that leg of lamb is more balanced in fatty acids than lamb shoulder. Legumes are a good source of protein but can have too many carbohydrates for those who are insulin resistant, and can also provoke inflammatory responses in people with autoimmune disorders. Soybeans, unless sprouted, contain about 20:1 omega-6's to omega-3's. Soy products in general must be fermented to be useful to our bodies, otherwise, you'll find them indigestible. When fermented, the balance of fatty acids is favorable. Most soybeans now are genetically modified. Although we have little data to go on here, traditional wisdom says this could not be a good thing. This is another area that you must trust your instincts. Raw nuts like Brazil nuts, white walnuts, and less so black walnuts are rich in omega-3's, low in omega-6's, and provide quality protein.. Aged cheeses are fine in moderation and even better when made from raw milk. I find a few of these in an Italian import store. Eggs are about 20:1 omega-6's to omega-3's. This is entirely due to the feed given to chickens. There are a few brands on the market now that are promoted as having higher omega-3's. The ratios for these brands range from 3:1 to 1:1 in omega-6's to 3's. They cost about a dollar more a dozen and are well worth it. You don't need to limit consumption of these eggs. The recently discovered category of fatty acids called Conjugated Linoleic acids (CLA) was originally found in ground beef. It seems to explain why beef is not as harmful as originally thought. CLA is an antioxidant said to be approximately two hundred times more powerful than beta carotene. It can be found in the fat of beef and dairy products, but the levels of CLA are unpredictable in all but grass-fed cows. Until more is known it is prudent to stick with grass-fed or very lean cuts of grain-fed beef. Trans-fats - Avoid them! They are very high in omega-6's. Some foods containing trans-fat are potato chips, corn chips, tortilla chips, doughs, cookies, cakes and cake mixes, crackers, muffins and muffin mixes, crackers, granola, and popcorn. You can identify them by the terms partially hydrogenated, non-fat dry milk solids, vegetable oils, and any other oils except those mentioned in the above category of oils. Some Final Thoughts A long-standing frustration of research scientists has been the lack of impact their findings have on media public policy, and mainstream health practitioners despite published studies. Most media is bound by advertisers' interests. My hypothesis about health practitioners is that they are no different from the majority of people. They go to school, learn what they are taught, and read what they are required to read. After gaining professional status, they do only what is required to keep their licenses due to hectic schedules. The work of researchers goes largely unread. Fortunately, this research is has been made readily available to the general public via the World Wide Web. This information empowers us to take charge of our own health and well-being. It is no coincidence that this information has recently become accessible. Trust what you are being shown. Remember, we are each biochemically unique. One exact dietary regimen does not fit all. Fortunately, the knowledge we're gaining about fatty acids seems to be an overarching nutritional principle. You can become more intuitive about your nutritional requirements by cleaning up your diet. Then, listen to your body. It will tell you everything you need to know. References: Nutrition: The Soft Science of Dietary Fat, 2001, Gary Taubes; Clinical Applications of Fatty Acid Profiling, 1999, Lord and Bralley; Transfat, 1998, Mary Enig and Sally Fallon; Ethnographic Atlas, 1997, GP Murdock; Reducing the Serum Cholesterol Level With a Diet Hih in Animal Fat, 1998, HL Newbold; The Dairy Education Board Weekly Newsletter, The Cream No Longer Rises to the Top,02/21/99; Lipids, Essential Fatty Acid Metabolism in Boys with Attention Deficit Disorder, 1992, Stevens, Zantall, et al; Journal of Nutrition, Prevention of Cardiac Arrhythmias by Dietary (N-3) Poly-unsaturated Fatty Acids and Their Mechanism of Action, Nair, Leach, Falconer, Garg, 1997; Oncology, The Role of Fatty Acids and Eicosanoid Synthesis Inhibitors in Breast Carcinoma, Noguchi, Rose, Earashi, Miyazaki, 1995; Proceedings of the American Society of Animal Science, Biosynthesis of Conjugated Linoleic Acid in Ruminants, Bauman, Baumgard, Corl, Griinari, 1999; Conjugated Linoleic Acid and Beneficial Effects on Human Health, McGuire and McGuire, 1999; numerous writings both public and private of Loren Cordain, Dean Esmay; Handbook of Plant Lectins: Properties and Biomedical Applications, Von Damme, Peumans, Pusztai, Bardocz, 1998; Lancet, What Triggers Autoimmunity, 1985; Lipids, Effect of Dietary Tranfatty Acids on Microsomal Enzymes and Membranes, Ostlund-Lindqvist, Albanus, Croon, 1985; Handbook of Lipids in Human Nutrition, CRC Press, Inc., 1996, American Journal of Clinical Nutrition, Dietary Polyunsaturated Fatty Acids and Depression: When Cholesterol Does Not Satisfy, Hibbeln and Salem, 1997; The Omega Plan, 1998, Artemis Simopoulos, MD and Jo Robinson; Townsend Newsletter, 1995, Julie Klotter, MD; Lancet, 1996, Cow's milk proteins are unique in one respectŠ; Diabetes Care, 1994, Link Between Milk and Juvenile Diabetes; Science, 1990, FDA Review of Genetically Engineered Milk Finds RBGH Treatment Increases Concentration of Insulin-like Growth Factors in Cow's Milk. 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