Los Angeles Times Editorial: Funding Can Taint Findings

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Los Angeles Times

24 January 2003

 

Editorial: Funding Can Taint Findings

 

[This editorial draws attention to the impact of vested interests on medical

research. It focuses on medical research, where most attention has been paid,

but fails to note that the problem it describes is even more severe in research

examining the health risks of chemical exposures.]

 

Last month, a study by the National Heart, Lung and Blood Institute showed that

diuretics were better at alleviating high blood pressure than newer, far more

expensive drugs such as calcium channel blockers. It took a federally funded

study, after years of studies lauding channel blockers, to uncover that. A New

England Journal of Medicine review of those favorable studies found that 96% of

the researchers received money from the drugs' makers. The folks footing the

bill for scientific research too often get exactly what they want. With industry

supplying nearly two-thirds of the medical research money in the United States,

that means more studies that boost industry in ways both subtle and blatant.

 

A new Yale University study finds that when businesses, rather than other

groups, sponsor medical research at hospitals and colleges, the outcomes are 3.6

times more likely to favor the company involved. The Yale study -- not funded by

business -- puts together an unlovely picture of what happens when researchers

have financial ties to the subject of their research.

 

The correlation between funding and findings makes it easy to understand why

consumer groups greeted with skepticism a study this week from the American

Assn. of Neurological Surgeons that found no link between roller coasters and

brain injury. The study's sponsor was Six Flags, owner of the

ever-more-turbulent rides at Magic Mountain and other parks.

 

This rush for business dollars -- once anathema to academic and medical

researchers -- extends far beyond medicine.

 

ExxonMobil is putting $100 million into the new Global Climate and Energy

Project at Stanford University. The project's agenda is developing ways to

combat the atmospheric accumulation of greenhouse gases from fossil fuels. But

ExxonMobil and other sponsoring companies have the authority to approve the

research topics, and the oil giant is no fan of renewable energy or limits on

carbon dioxide emissions. A company official said Stanford was chosen in part

because it is known for working with business and because the professors were

open to changing their career directions to join the project.

 

Public spending on medical research has doubled in the last five years but

cannot keep up with corporations intent on buying academic credibility.

Researchers can raise the bar by setting standards and urging companies to fund

studies through independent foundations.

 

Journals and the popular media should ask for, and prominently publish, funding

sources and amounts whenever they report on new research. The forces shaping

science also shape public policy and medical practice.

 

 

 

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