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http://www.alternet.org/story.html?StoryID=14821

Water is Becoming a Dangerous DrugMelissa Knopper, E Magazine

December 19, 2002

Birth control pills, estrogen replacement drugs, ibuprofen, bug spray,

sunscreen, mouthwash and antibacterial soap: all of these products could turn up

in your next glass of tap water, according to the United States Geological

Survey (USGS). Last summer, USGS scientists sampled 139 rivers and streams,

finding hundreds of prescription and over-the-counter drugs and personal care

products lingering in the nation's water supply.

 

 

In many cases, these tiny drug particles were found in river water that is

recycled -- flowing from one city's sewer plant into another city's drinking

water system. Many cities can't afford the charcoal filters required to screen

out the final traces of these byproducts, so they end up in the drinking water,

experts say. Rural homeowners who use well water are at an even greater risk.

USGS researchers also turned up antibiotics in nearly half the streams that were

sampled, raising other concerns about the nation's growing antibiotic resistance

problem. " This study raised a bunch of red flags, " says Dana Kolpin, lead author

of the USGS study. " At these low concentrations, I think there are going to be

long-term effects that may take several generations to show up. "

 

A Threat to Reproductive Health

 

The dangers of endocrine-disrupting water pollutants such as dioxin and

polychlorinated biphenyls (PCBs) are well known -- they have been linked to a

variety of reproductive health problems, from endometriosis to low sperm counts.

Synthetic hormones in the water may have similar health effects -- on both

people and wildlife -- at very low levels of exposure. " All of these compounds

are going into a chemical soup, " says Theo Colborn, senior scientist at the

World Wildlife Fund (WWF) and author of " Our Stolen Future. "

 

Colborn says she is worried about pharmaceutical estrogens mixing with chemicals

already present in streams. " You can liken it to side effects you get with a

prescription drug -- you don't know how it's going to interact with the

over-the-counter drugs you're taking, " Colborn says. " It's the unexpected,

interactive effects we never predicted that are a real concern. "

 

For example, Colborn says, bisphenol A, a component of plastic that is also used

as a fire retardant, causes female mice to reach puberty earlier than normal.

Bisphenol A forms a weak bond with the body's estrogen receptors. It can

scramble a cell's natural communication system and cause it to replicate too

quickly. That, in turn, raises concerns about breast cancer in humans. What

happens if this compound, which is active at low levels of exposure, combines

with estrogen from a birth control pill in the water? At this point, it's still

unclear. Colborn says, " It could have long-term health effects. "

 

These estrogens also could have an additive effect with chemicals such as PCBs,

which are found in animal tissue. A recent study by researchers at Michigan

State University found mink that were fed a diet of PCB-laden fish from the

polluted Housatonic River in Connecticut had offspring with lower birth weights

and higher infant mortality rates. Housatonic Riverkeeper Tim Gray, a member of

the New York-based Waterkeeper's Alliance, wonders if PCBs interfere with the

mink's reproduction, what will synthetic estrogen and other drugs do?

 

Until recently, people thought the estrogens in birth control pills were

rendered inactive by the body because the kidneys tack on an extra sugar

molecule before they are excreted, says William Owens, a toxicologist who

researched estrogen patches for Procter & Gamble. But now, scientists have

learned bacteria in sewage treatment plants chew off that sugar molecule.

 

A British researcher, John Sumpter, contributed to this discovery while studying

fish living near a London wastewater treatment plant. He found male fish that

were producing eggs. After he found the compound estradiol in the fish tissue,

he concluded estrogens from birth control pills were part of the problem.

 

Antibiotic Resistance is Growing

 

Another active area of research and debate is antibiotic resistance. The Union

of Concerned Scientists says farmers use 70 percent of antibiotics in the United

States. Large factory farms use antibiotics to prevent confined,

crowded-together cows or chickens from getting sick. But that practice is

creating " superbugs, " such as virulent strains of salmonella that can be deadly

to humans and difficult to treat. Those superbugs typically are spread to

consumers through contaminated meat, but people who drink from private wells

also are vulnerable, says Dr. John Balbus, director of the environmental health

program for Environmental Defense.

 

Meanwhile, thousands of pounds of triclosan -- the active ingredient in

antibacterial soaps, deodorants, sponges and household cleaners -- are also

going down the drain into our waterways. Susan Cellura, a spokesperson for Ciba

Specialty Chemicals, which manufactures triclosan, says the chemical does not

contribute to the antibacterial resistance problem. She quotes a recent report

by the European Commission's Scientific Steering Committee, which concludes:

" There is no convincing evidence that triclosan poses a risk to humans or the

environment by inducing or transmitting antibacterial resistance under current

conditions of use. " Ciba's research also purports to show that triclosan does

not pose any health threat to wildlife or humans because it's present in water

at very low levels, 0.1 part per billion.

 

" This is well below the 'safe' level of 0.7 parts per million established by

research, " Cellura says. But other studies have shown that triclosan does

contribute to the resistance problem. Because triclosan is a broad-spectrum

antimicrobial agent, it kills all bacteria on the body and household surfaces --

even the beneficial kind. That, in turn, creates an environment where the

superbugs can flourish, says a Tufts University study. The Tufts researchers

also argue that the levels of triclosan in common handsoaps and cleaners are not

strong enough to kill certain harmful bacteria. In an August report, the

American Medical Association called on the scientific community to do a more

thorough review of whether antibacterial consumer products do more harm than

good. " The use of these products have never been shown to be superior, to my

knowledge, to regular soap and water, " says Dr. Tamar Barlan, director of the

Center for Science in the Public Interest's project on antibiotic resistance.

 

Protect Yourself -- and the Environment

 

So what are the solutions? Legislation could be one option. The government

could, for example, require all cities that use treated wastewater for drinking

to install charcoal filters, although that would be costly. That type of

legislation won't likely be passed until research pinpoints exactly how risky

these substances can be for humans and wildlife. But until recently, says Kolpin

of the USGS, researchers had no way to even measure these compounds at the very

low levels they appear in streams. The Waterkeeper Alliance's Gray joins the WWF

and other green groups in the call to enact stronger clean water laws. " This new

report paints a scary picture of what's out there in our rivers and lakes, " he

says.

 

In the meantime, consumers can protect themselves and the environment. WWF's

Colborn recommends drinking distilled water, possibly produced by your own

distiller system. If you must buy bottled water, she adds, pour it into a glass

container instead of leaving it in the plastic bottle. Other steps include:

 

 

Use condoms instead of birth control pills;

 

Choose natural menopause remedies instead of prescription hormone replacement

therapy drugs;

 

Return old prescriptions to the pharmacy rather than flushing them down the

toilet;

 

Avoid unnecessary use of antibiotic drugs, and try plain old soap and water

unless your doctor recommends antibacterial soap for medical reasons;

 

Switch to antibiotic-free meat or a vegetarian diet.

 

 

Author's Note: For more information, contact:

Campaign to End Antibiotic Overuse, (202)572-3250;

KeepAntibioticsWorking.com;

The original USGS study;

Our Stolen Future;

Waterkeeper Alliance, (914)674-0622.

 

Melissa Knopper is a Denver-based science writer.

 

 

 

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