Nicotinamide adenine dinucleotide, or NADH, is a coenzyme made from vitamin B2, or niacin.

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NADH What Is It? Nicotinamide adenine dinucleotide, or NADH, is a coenzyme made

from vitamin B2, or niacin. It’s present in all living cells. As a coenzyme,

NADH serves an important role in helping enzymes to function as they should. (An

enzyme is a protein that works like a catalyst in the body to prompt chemical

changes in other substances; breaking down food into energy is an example.)

Most coenzymes are synthesized from vitamins, and for optimal energy production,

the body needs good amounts of them. The coenzyme, NADH, is no exception.In

people, NADH stimulates the production of ATP (adenosine triphosphate), a

compound that regulates the release of energy stored in cells. The more NADH a

cell has, the more chemical energy it produces.Research findings indicate that

increased concentrations of NADH in the brain may boost the production of

neurotransmitters brain chemicals vital to sound mental function. Until

recently, NADH could only be given intravenously because stomach acid would

rapidly destroy the delicate molecule. But a new enteric-coated, oral tablet

containing NADH is now available. Health Benefits Oral NADH supplementation

has been used to combat simple fatigue as well as such mysterious and

energy-sapping disorders as chronic fatigue syndrome and fibromyalgia.

Researchers are also studying the value of NADH supplements for improving mental

function in people with Alzheimer's disease, and minimizing physical disability

and relieving depression in people with Parkinson's disease. Some healthy

individuals also take NADH supplements orally to improve concentration and

memory capacity, as well as to increase athletic endurance. However, to date

there have been no published studies to indicate that using NADH is in any way

effective or safe for these purposes.Specifically, NADH may help to:

Relieve chronic fatigue syndrome. A recent study supported by the Food and Drug

Administration found that the oral form of NADH helped a small group of patients

with chronic fatigue syndrome. In the study, 31% of the participants said they

felt more vigorous and mentally alert when taking daily NADH. Only 8% of those

taking the placebo reported such improvements. Lift general fatigue as well as

fibromyalgia-related exhaustion. Because NADH increases energy in cells, some

researchers speculate that it may also boost energy in people with fibromyalgia,

a disorder characterized by muscle pain and fatigue. NADH may also keep simple,

daily fatigue at bay by helping to supply muscle cells with energy. Relieve

depression. Imbalances in brain chemicals are a primary cause of certain types

of depression. Because NADH stimulates the production of many key chemicals

called neurotransmitters, it may have a role to play in relieving the symptoms

of depression. No clinical trials to demonstrate this effect have been conducted

so far, however. Complement Parkinson's therapy. There is early evidence that

NADH supplements may raise levels of dopamine, a compound crucial to slowing the

physical symptoms of Parkinson's disease and relieving the depression that often

accompanies them. (People with Parkinson’s disease have dwindling supplies of

dopamine.) Improve Alzheimer's symptoms. Some European studies of NADH have

shown promise for treating people with Alzheimer's disease, but as of yet, no

well-designed double-blind, placebo-controlled trials have been conducted to

demonstrate this effect. One preliminary study did show that cognitive

dysfunction improved in a very small group of Alzheimer's patients taking NADH.

Forms tablet

Dosage Information Special Tips:--To reduce the risk of side effects, such as

jitteriness and mild overstimulation, start out with a small oral dose (2.5 mg a

day) for a couple of weeks, gradually increasing the dose over a period of two

to three weeks.

For chronic fatigue syndrome, 2.5 mg twice a day for 10 days or one package,

then 5 mg twice a dayFor fatigue, 2.5 mg twice a day for 10 days or one package,

then 5 mg twice a dayFor fibromyalgia, 2.5 mg twice a day for 14 days (or one

package, see label), then 5 mg twice a dayFor Parkinson's disease, 5 mg a day,

gradually increasing over two weeks to 10 mg twice a day.For Alzheimer's

disease, 5 mg twice a day Guidelines for Use

Take NADH with water on an empty stomach. General Interaction There are no known

drug or nutrient interactions associated with NADH in oral or injectable form,

although more research is needed. Possible Side Effects

High doses of NADH (10 mg a day or more) may cause jitteriness, anxiety, and

insomnia. Cautions

The safety of long-term treatment with oral NADH remains unclear. Most sources

recommend using it for periods of no more than four months, then taking a month

off before starting again. An alternative is to take it only two or three times

a week, rather than daily. Ailments Dosage

Alzheimer's Disease 5 mg twice a day

Chronic Fatigue Syndrome 2.5 mg twice a day for 10 days or one package, then 5

mg twice a day

Fatigue 2.5 mg twice a day for 10 days or one package, then 5 mg twice a day

Fibromyalgia 2.5 mg twice a day for 14 days (or one package, see label), then 5

mg twice a day

Parkinson's Disease 5 mg a day, gradually increasing over two weeks to 10 mg

twice a day.

 

 

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[Guest guest]

I have a friend who was taking care of his aged mother, who had Parkinson's

Disease. She began to hallucinate due to the dose of Sinemet she was on for this

disease. My friend began to do research and finally he actually talked by phone

to Dr. Birkmeyer in. . .where was that? Austria or Vienna. Anyway, Dr. Birkmeyer

gave him advice about how much NADH go give his mother so that she could cut

back that Sinemet, and how far they could try cutting that back There was a big

fight with her doctor, who used all kinds of intimidating scare tactics to talk

them out of it. But they did it anyway, and were able to keep her Parkinson's

under control with a minimal dose of Sinemet and Enada, which at the time was

the brand of NADH of choice. No more frightening hallucinations! It was a very

happy story. Later, Beth

 

 

 

 

 

 

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