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JUST SHARING

LOVE YOUR FRIEND IN HEALTH

BREE

Original article:

<A

HREF= " http://aolsvc.health.webmd.aol.com/content/Article/57/65959.htm " >http://ao\

lsvc.health.webmd.aol.com/content/Article/57/65959.htm</A>

Perspective on Herbal Remedies

 

By <A

HREF= " http://aolsvc.health.webmd.aol.com/content/Biography/7/1756_50703.htm " >Jea\

nie Davis</A>

WebMD Medical News Reviewed By <A

HREF= " http://aolsvc.health.webmd.aol.com/content/Biography/7/1756_53424.htm " >Mic\

hael Smith, MD</A>

on Wednesday, December 18, 2002

 

Dec. 18, 2002 -- Herbal medicines come under scrutiny in a leading medical

journal this week. Millions are trying echinacea, ginkgo biloba, St. John's

wort, and many, many more. But researchers pose serious questions regarding

their quality, safety, and effectiveness.

 

" We are in the midst of a public health experiment that much of academic

medicine has failed to acknowledge until recently, " writes Stephen E. Straus,

MD, director of the National Center for Complementary and Alternative

Medicine, a branch of the National Institutes of Health.

 

In the Dec. 19 issue of The New England Journal of Medicine, Straus and

others voice their opinions about herbal medicines.

 

One big problem: Herbal products are regulated as dietary supplements and are

therefore not subject to quality and safety requirements that other drugs

must meet. " With herbal medicines, what is on the label may not be what is in

the bottle, " writes Straus. " Just because an herb is natural does not mean

that it is safe, and claims of remarkable healing powers are rarely supported

by evidence. "

 

Regulation is a big issue. In the U.S., the herbal product manufacturer " is

permitted to claim the product affects the structure or function of the body,

as long as there is no claim of effectiveness, " writes Peter A.G.M. De Smet,

PharmD, PhD, researcher with the Scientific Institute Dutch Pharmacists in

the Netherlands.

 

" Contrary to popular belief, the use of herbal remedies can pose serious

health risks, " says De Smet. There can be direct adverse effects from the

herbals. Also, the interaction of herbals and prescription drugs can be

harmful.

 

For example, St. John's wort has been found to seriously reduce the

effectiveness of certain drugs, such as cyclosporine -- a drug used to

prevent organ rejection after transplant -- HIV drugs, and certain

chemotherapy drugs.

 

Donald M. Marcus, MD, with Baylor College of Medicine in Houston, also

appeals for new regulation of herbals.

 

 

Because there are no standards, herbals rarely are the same from batch to

batch, says Marcus. Plants are grown under various conditions, different

plant species might be used, and there may even be differences in harvesting

and processing of extracts, he writes. Also, herbal extracts have been found

to contain undeclared pharmaceuticals or heavy metals.

 

Case in point: Until recently, thousands of American men with advanced

prostate cancer were using PC-SPES, a mixture of eight herbs formulated

according to principles of traditional Chinese medicine. Preliminary studies

suggested that PC-SPES lowered prostate-specific antigen levels but often at

the cost of breast tenderness and loss of libido.

 

 

But early this year, the California Department of Health Services reported

that PC-SPES is contaminated with diethylstilbesterol (a synthetic estrogen

used years ago to prevent premature labor and miscarriage) and warfarin (a

blood thinner). The product was withdrawn from store shelves and production

of PC-SPES ceased. Yet patients have been enticed by similar herbal

" cocktails " that were marketed promptly by other companies.

 

But the United States Pharmacopeia (USP), an independent agency that serves

as the government's official compendium for dietary supplement standards,

announced yesterday that it has begun to issue certification on hundreds of

products that it has independently tested as part of its Dietary Supplement

Verification Program (DSVP).

 

Despite all the challenges, herbal medicines show great promise and should

not be neglected, says Straus.

 

In fact, the recent discovery of a new class of drugs to fight malaria -- a

group of Chinese herbs called artemisinins -- " indicate that we have not yet

surveyed all of nature for its healing potential, " says Straus. " However,

both the quality of the data and the quality of the herbal products

themselves must improve greatly if herbal medicines are to assume a respected

place in the contemporary health care armamentarium. "

 

Most funding right now supports preclinical and early-phase trials, but a few

products -- such as ginkgo biloba and St. John's wort -- have been deemed

ready for large-scale investigations, Straus says.

 

SOURCES: The New England Journal of Medicine, Dec. 19, 2002; WebMD Medical

News, " <A

HREF= " http://aolsvc.health.webmd.aol.com/content/article/57/65942.htm " >FDA

Designate to Certify Supplements</A> " ; WebMD Medical News, " <A

HREF= " http://aolsvc.health.webmd.aol.com/content/article/50/40324.htm " >Prostate

Cancer Supplement Contaminated</A>. "

 

 

 

© 2002 WebMD Inc. All rights reserved.

 

 

 

 

 

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Dear Group,

 

I hope that most people in the group realize that this type of news

article is part of a constant PR campaign to do away with the

potential competition to the drug companies in it's mission

to " educate " and " protect " the public.

 

I wish someone would educate the people about the dangers of some

prescription drugs.

 

This type information is repeated countless times in the media till

it even shows up in alternative health groups.

 

That is why we have included the quote from Linus Pauling on our

front page.

 

" Do not let either the medical authorities or the politicians mislead

you. Find out what the facts are, and make your own decisions about

how to live a happy life and how to work for a better world. " - Linus

Pauling

 

moderator - gettingwell

 

 

Gettingwell , ImWoman42@a... wrote:

> JUST SHARING

> LOVE YOUR FRIEND IN HEALTH

> BREE

> Original article:

> <A

HREF= " http://aolsvc.health.webmd.aol.com/content/Article/57/65959.htm "

>http://aolsvc.health.webmd.aol.com/content/Article/57/65959.htm</A>

> Perspective on Herbal Remedies

>

> By <A

HREF= " http://aolsvc.health.webmd.aol.com/content/Biography/7/1756_5070

3.htm " >Jeanie Davis</A>

> WebMD Medical News Reviewed By <A

HREF= " http://aolsvc.health.webmd.aol.com/content/Biography/7/1756_5342

4.htm " >Michael Smith, MD</A>

> on Wednesday, December 18, 2002

>

> Dec. 18, 2002 -- Herbal medicines come under scrutiny in a leading

medical

> journal this week. Millions are trying echinacea, ginkgo biloba,

St. John's

> wort, and many, many more. But researchers pose serious questions

regarding

> their quality, safety, and effectiveness.

>

> " We are in the midst of a public health experiment that much of

academic

> medicine has failed to acknowledge until recently, " writes Stephen

E. Straus,

> MD, director of the National Center for Complementary and

Alternative

> Medicine, a branch of the National Institutes of Health.

>

> In the Dec. 19 issue of The New England Journal of Medicine, Straus

and

> others voice their opinions about herbal medicines.

>

> One big problem: Herbal products are regulated as dietary

supplements and are

> therefore not subject to quality and safety requirements that other

drugs

> must meet. " With herbal medicines, what is on the label may not be

what is in

> the bottle, " writes Straus. " Just because an herb is natural does

not mean

> that it is safe, and claims of remarkable healing powers are rarely

supported

> by evidence. "

>

> Regulation is a big issue. In the U.S., the herbal product

manufacturer " is

> permitted to claim the product affects the structure or function of

the body,

> as long as there is no claim of effectiveness, " writes Peter A.G.M.

De Smet,

> PharmD, PhD, researcher with the Scientific Institute Dutch

Pharmacists in

> the Netherlands.

>

> " Contrary to popular belief, the use of herbal remedies can pose

serious

> health risks, " says De Smet. There can be direct adverse effects

from the

> herbals. Also, the interaction of herbals and prescription drugs

can be

> harmful.

>

> For example, St. John's wort has been found to seriously reduce the

> effectiveness of certain drugs, such as cyclosporine -- a drug used

to

> prevent organ rejection after transplant -- HIV drugs, and certain

> chemotherapy drugs.

>

> Donald M. Marcus, MD, with Baylor College of Medicine in Houston,

also

> appeals for new regulation of herbals.

>

>

> Because there are no standards, herbals rarely are the same from

batch to

> batch, says Marcus. Plants are grown under various conditions,

different

> plant species might be used, and there may even be differences in

harvesting

> and processing of extracts, he writes. Also, herbal extracts have

been found

> to contain undeclared pharmaceuticals or heavy metals.

>

> Case in point: Until recently, thousands of American men with

advanced

> prostate cancer were using PC-SPES, a mixture of eight herbs

formulated

> according to principles of traditional Chinese medicine.

Preliminary studies

> suggested that PC-SPES lowered prostate-specific antigen levels but

often at

> the cost of breast tenderness and loss of libido.

>

>

> But early this year, the California Department of Health Services

reported

> that PC-SPES is contaminated with diethylstilbesterol (a synthetic

estrogen

> used years ago to prevent premature labor and miscarriage) and

warfarin (a

> blood thinner). The product was withdrawn from store shelves and

production

> of PC-SPES ceased. Yet patients have been enticed by similar herbal

> " cocktails " that were marketed promptly by other companies.

>

> But the United States Pharmacopeia (USP), an independent agency

that serves

> as the government's official compendium for dietary supplement

standards,

> announced yesterday that it has begun to issue certification on

hundreds of

> products that it has independently tested as part of its Dietary

Supplement

> Verification Program (DSVP).

>

> Despite all the challenges, herbal medicines show great promise and

should

> not be neglected, says Straus.

>

> In fact, the recent discovery of a new class of drugs to fight

malaria -- a

> group of Chinese herbs called artemisinins -- " indicate that we

have not yet

> surveyed all of nature for its healing potential, " says

Straus. " However,

> both the quality of the data and the quality of the herbal products

> themselves must improve greatly if herbal medicines are to assume a

respected

> place in the contemporary health care armamentarium. "

>

> Most funding right now supports preclinical and early-phase trials,

but a few

> products -- such as ginkgo biloba and St. John's wort -- have been

deemed

> ready for large-scale investigations, Straus says.

>

> SOURCES: The New England Journal of Medicine, Dec. 19, 2002; WebMD

Medical

> News, " <A

HREF= " http://aolsvc.health.webmd.aol.com/content/article/57/65942.htm "

>FDA Designate to Certify Supplements</A> " ; WebMD Medical News, " <A

HREF= " http://aolsvc.health.webmd.aol.com/content/article/50/40324.htm "

>Prostate

> Cancer Supplement Contaminated</A>. "

>

>

>

> © 2002 WebMD Inc. All rights reserved.

>

>

>

>

>

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