Guest guest Posted March 9, 2005 Report Share Posted March 9, 2005 Good Morning! The Carotenoids Carotenoids, of which beta-carotenes are the most popular, are found in many fruits and vegetables, animals, plants and microorganisms. The body converts beta carotene into Vitamin A. Vitamin A is a fat- soluble vitamin essential for vision, growth, cell division, reproduction and immunity. Among the 600 or more carotenoids in foods, beta-carotene, lycopene, and lutein are well-known leaders in the fight to reduce the damage from free radicals. Some studies have shown that beta-carotene may be an effective ally against prostate cancer. A recent study found men with the lowest level of beta-carotene in their blood were at the greatest risk of developing this cancer. [1]. Lycopene, a carotenoid found in tomatoes, is one of the most powerful antioxidants. Lycopene is the most predominant carotenoid in human plasma. Lycopene presents naturally in greater amounts than beta- carotene and other dietary carotenoids. Lycopene levels are affected by several biological and lifestyle factors. Because of its lipophilic nature, lycopene concentrates in low-density lipoprotein portions of the serum. Lycopene is also found in the adrenal, liver, testes, and prostate. However, unlike other carotenoids, lycopene levels in serum or tissues do not correlate with overall intake of fruits and vegetables. [2]. Research shows that lycopene can be absorbed more efficiently by the body after it has been processed into juice, sauce, paste, or ketchup. [2]. In fresh fruit, lycopene is enclosed in the fruit tissue. Therefore, only a portion of the lycopene that is present in fresh fruit is absorbed. Lycopene appears to protect against many diseases, including cancers of the mouth, pharynx, esophagus, stomach, colon, and rectum. [2]. Another study showed that women with the highest levels of lycopene in their blood were five times less likely to develop precancerous signs of cervical cancer than women with the lowest levels. [3]. Lutein is another carotenoid found in vegetables and fruits. Lutein acts as an antioxidant, protecting cells against the damaging effects of free radicals. The central area of the retina in humans and primates is called the macula and contains lutein as the primary carotenoid. Lutein acts to filter and shield harmful blue light from the eye and may decrease the risk of developing macular degeneration, the eye disease that afflicts one in three people over age 65. [4]. Smokers who consumed the most beta-carotene and flavonoids from food, also appeared to cut their Alzheimer's risk. [5]. Yet, smokers who take excessive beta carotene supplements may increase their risk of lung cancer. [6]. A recent study has also shown the risk of osteoperosis with excessive Vitamin A. Retinol is the direct form of vitamin A found in most multivitamins, cod liver oil, liver, fortified foods, and whole milk products. Dietary retinol is associated with fractures, beta carotene is not. Beta carotene, which is converted to Vitamin A by the body, is not associated with any increased risk of fracture. [7]. This study has shown that intake of vitamin A or beta carotene, can be best obtained by eating more red and yellow vegetables than taking supplements. The recommended safe upper limit of retinol is 3000 mcg (9900 IU) per day. This includes all sources of retinol, including foods such as liver, dietary supplements such as cod liver oil and vitamin A supplements, fortified foods such as cereals, and multivitamins. Foods high in carotenoids include red, orange, deep-yellow, and some dark-green leafy vegetables, such as tomatoes, carrots, cantaloupe, pumpkin, sweet potatoes, winter squash, brussel sprouts, spinach, kale and broccoli. Andrew Pacholyk, MS, L.Ac. Peacefulmind.com Therapies for healing mind, body, spirit References 1. Heinonen OP, Albanes D, Virtamo J, Taylor PR, Huttunen JK, Hartman AM, Haapakoski J, Malila N, Rautalahti M, Ripatti S, Maenpaa H, Teerenhovi L, Koss L, Virolainen M, Edwards BK. Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. Department of Public Health, University of Helsinki, Finland. Journal National Cancer Institute. 1998 Mar 18;90(6):440-6, 441-7. 2. Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willerr WC. Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst 87:1767-1776, 1995 3. Dorgan JF, Sowell A, Swanson CA, Potischman N, Miller R. Schussler N, Stephenson HEJr. Relationships of serum carotenoids, retinol, a-tocopherol and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri (United States). Cancer Causes Control 9:89-97, 1998 4. Antioxidants and age-related macular degeneration. Age-Related Macular Degeneration Study Group. Journal of the American Optometric Association. January 1996--Vol 67, No. 1. 5. Dr. Marianne J. Engelhart of the Erasmus Medical Center in Rotterdam, the Netherlands: Those with the highest intake of vitamin C and vitamin E from food appeared to be the least likely to develop Alzheimer's disease. The Journal of the American Medical Association. 6/26/03 6. Albanes D, Heinonen OP, Taylor PR, Virtamo J, Edwards BK, Rautalahti M, Hartman AM, Palmgren J, Freedman LS, Haapakoski J, Barrett MJ, Pietinen P, Malila N, Tala E, Liippo K, Salomaa ER, Tangrea JA, Teppo L, Askin FB, Taskinen E, Erozan Y, Greenwald P, Huttunen JK. Beta Carotene and Lung Cancer., J Natl Cancer Inst. 1996 Nov 6;88(21):1560-70. 7. Serum retinol levels and the risk of fracture. K. Michaëlsson, H. Lithell, B. Vessby, et al., New Engl J Med, 2003, vol. 348, pp. 287— 294 Quote Link to comment Share on other sites More sharing options...
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