DMAE: Natural Brain Chemistry

July 17, 2003

Good Morning!

DMAE (Dimethylaminoethanol) is a chemical naturally produced in the

human brain. It is thought to be used by the body in converting the

precursor choline to the neurotransmitter, acetylcholine. [47,49,51]

Lipofuscin is a cellular pigment consisting of aggregated molecular

waste. It tends to occur in the cells of people over 40 years old. It

is thought that lipofuscin is not simply a byproduct of aging but may

also contribute to the aging process. Neurons, heart and skin of

older people usually contain particularly large amounts of

lipofiscin. DMAE has shown that it reduced the accumulation of

lipofuscin deposits inside cells. [51,52]

DMAE was found helpful in patients with age related cognitive

decline. DMAE was given in a dosage of 600 mg a day for four weeks to

fourteen older patients. Ten patients improved and four were

unchanged. The patients on DMAE had reduced depression, less anxiety,

and increased motivation, but they had no improvement in memory.

[48]. The researchers suggest that although DMAE may not improve

memory, it may produce positive behavioral changes in some dementia

patients. [47].

DMAE has been looked at for its anti-inflammatory agent as an anti-

aging nutrient. A recent study shows DMAE cream is able to increase

firmness of skin. [50,52]

Most people notice being more alert and focused within a couple of

hours after taking DMAE orally. The effects can last most of the day.

It is best to take DMAE early part of the day. DMAE is available in

dosages ranging from 100 to 400 mg.

It is best to start with a low dose, such as 50 to 150 mg since high

doses can cause anxiety, restlessness, and muscle tension in the neck

and shoulders. DMAE taken late in the day may cause insomnia. [52].

DMAE can be found in cold water fish such as sardines and salmon.

Andrew Pacholyk LMT, MT-BC, CA

Peacefulmind.com

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