Guest guest Posted December 14, 2002 Report Share Posted December 14, 2002 Interesting article Vitamin C Beneficial In Heart Disease A DGReview of : " Vitamin C Preserves Endothelial Function in Patients with Coronary Heart Disease after a High-Fat Meal " Clinical Cardiology 05/27/2002 By Robert Short Vitamin C treatment has a possible role in benefiting patients with coronary heart disease by countering the adverse effects of a high-fat meal. The postprandial serum triglyceride concentration is raised after a high-fat meal and this postprandial state is critical in atherogenesis, inducing endothelial dysfunction through an oxidative stress mechanism. These were the findings of a study that included 74 patients with coronary heart disease and 50 people without the disease but who had risk factors. These two groups were split into subgroups: those who received 2 g of vitamin C and those who did not after eating high-fat meal. The study was conducted by Dr Ling Liu, Department of Cardiology, Hunan University, Hunan, People's Republic of China, and co-workers. They found that postprandial serum triglyceride concentration increased significantly at two to five hours after the high-fat meal in all groups. The fasting flow-mediated dilatation and nitroglycerin-induced dilatation of patients with coronary heart disease were impaired compared with those without disease. Although the postprandial flow-mediated dilatation was significantly aggravated in people not taking vitamin C (both with and without heart disease), this parameter in patients and subjects taking vitamin C showed no significant change. Clin Cardiol 2002;25:219-224 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2002 Report Share Posted December 17, 2002 Sounds interesting, but would you please explain what it means in lay man's terms? Thanks. Morton Donna wrote: > Interesting article > > Vitamin C Beneficial In Heart Disease > A DGReview of : " Vitamin C Preserves Endothelial Function in Patients with > Coronary Heart Disease after a High-Fat Meal " > Clinical Cardiology > 05/27/2002 > By Robert Short > > Vitamin C treatment has a possible role in benefiting patients with coronary > heart disease by countering the adverse effects of a high-fat meal. > > The postprandial serum triglyceride concentration is raised after a high-fat > meal and this postprandial state is critical in atherogenesis, inducing > endothelial dysfunction through an oxidative stress mechanism. > > These were the findings of a study that included 74 patients with coronary > heart disease and 50 people without the disease but who had risk factors. > These two groups were split into subgroups: those who received 2 g of > vitamin C and those who did not after eating high-fat meal. > > The study was conducted by Dr Ling Liu, Department of Cardiology, Hunan > University, Hunan, People's Republic of China, and co-workers. > > They found that postprandial serum triglyceride concentration increased > significantly at two to five hours after the high-fat meal in all groups. > The fasting flow-mediated dilatation and nitroglycerin-induced dilatation of > patients with coronary heart disease were impaired compared with those > without disease. > > Although the postprandial flow-mediated dilatation was significantly > aggravated in people not taking vitamin C (both with and without heart > disease), this parameter in patients and subjects taking vitamin C showed no > significant change. > Clin Cardiol 2002;25:219-224 > > Getting well is done one step at a time, day by day, building health > and well being. > > list or archives: Gettingwell > > ........ Gettingwell- > post............. Gettingwell > digest form...... Gettingwell-digest > individual emails Gettingwell-normal > no email......... Gettingwell-nomail > moderator ....... Gettingwell-owner > ...... Gettingwell- > > > > Quote Link to comment Share on other sites More sharing options...
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