Diabetic Kidney Disease

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*§ Health and Healing §* ; *§ HH_Newsletter §*

Saturday, June 15, 2002 8:36 AM

[HH_Newsletter] Diabetic Kidney Disease

 

 

http://www.ravnskov.nu/index.htm

 

Diabetic Kidney Disease

(Diabetic Nephropathy)

 

In many countries diabetic nephropathy has become the most common cause of

end-stage renal failure. It is a common belief that the complications to

diabetes, including renal disease, is due to maltreatment of the diabetic

condition. However, many studies have shown that this is only part of the truth,

because many patients develop severe diabetic complications in spite of a

meticulous control of the blood glucose level, and most diabetic patients

survive for many years with a normal kidney function in spite of a badly

controlled diabetes.

 

Other factors obviousoly contribute to the development of kidney disease in

diabetic patients. One factor may be exposure to toxic chemicals because what

has been said about glomerulonephritis in the previous sections seems to be

valid for diabetic nephropathy also. This appears from two recent case-control

studies.

 

In one of the studies 113 patients with juvenile diabetes for at least ten years

were asked for hydrocarbon exposure since the diagnosis of diabetes had been

settled. The exposure was minimal in a group of 45 patients without signs of

kidney disease. In a group of 37 patients with microalbuminuria, the mildest

form of diabetic kidney disease, and in a group of 31 patients with established

nephropathy the exposure was significantly higher than in the first group, most

pronounced in the group with overt kidney disease. Those with significant

exposure had mainly been exposed to petroleum products, greasing and degreasing

agents, paints and glues (Yaqoob et al 1994).

 

Another study included 39 patients with diabetic nephropathy and chronic renal

failure. Compared with healthy control individuals the diabetic patients had

been more often exposed to a variety of chemicals, including lead (28% exposed

against 9.9% of the control individuals), welding fumes (18% against 7%),

silicon-containing compounds (26% against 8.8%), chromium (23% against 3.7%) and

hydrocarbons (39% against 25.7%) (Nuyts et al 1995).

 

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