Guest guest Posted April 4, 2002 Report Share Posted April 4, 2002 FriendsForHealthNaturally, " mrsjoguest " <joguest@m...> wrote: What Is So Important About Glucosamine and Chondroitin? by Dr. Douglas McFarland, M.D. Glucosamine and chondroitin are the unique " building block " molecules found in the cartilage of joints. Cartilage provides cushioning in the joints, like a spring, softening the damaging, harsh jolts to each joint with exercise or just everyday activities. Glucosamine and chondroitin sulfate are also building blocks of synovial fluid, which lubricates the joint like oil. Excessive wear and tear on the joint causes damage and loss of this cartilage cushion and synovial lubricant. Over the years, this constant trauma to the joint leads to osteoarthrits and chronic pain. The exact way these substances work in the joint is not completely known. Animal studies have shown that when chondroitin is taken orally, it accumulates in the joint, and may neutralize destructive enzymes that would otherwise cause cartilage damage.1 Laboratory tests dating back to the 1950's showed that glucosamine sulfate stimulated cartilage production in special cells found in joints. Some researchers believe that glucosamine is effective only in the sulfate form, due to the importance of sulfur in the production of normal connective tissue.2 Although the benefits of glucosamine and chondroitin sulfate for animal joint problems had been known for many years, Dr. Jason Theodasakis' book The Arthritis Cure forced the medical community to investigate their use in people. Since that time, many studies have shown they work in humans too! In the most recent study of these two substances, researchers from the Arthritis Center, Boston University School of Medicine, reviewed fifteen human studies on the use of glucosamine and chondroitin for joints.3 The results of this meta-analysis showed a significant improvement in joint pain for patients using either substance. Each underlying individual study also showed them to be extremely safe, with almost no side-effects. The range of doses were 500 to 1,500 mg of glucosamine and 800 to 1,200 mg of chondroitin daily in the sulfate form. A second meta-analysis of the effects of chondroitin on arthritis by Leeb, was similarly positive.4 In both studies, reliable benefits took 4 to 8 weeks to occur. The National Institutes of Health (NIH) is currently sponsoring a large study on these two substances. Their data will likely confirm what almost 30 previous studies have shown, that glucosamine and chondroitin sulfate help reduce arthritis pain and may even promote cartilage regrowth. 1 Ronca F, et al. Anti-inflammatory activity of chondroitin sulfate. Osteoarthritis Cartilage 1998;6(Suppl A):14-21. 2 Kelly GS. The role of glucosamine sulfate and chondroitin sulfates in the treatment of degenerative joint disease. Alt Med Rev 1998;3 (1):27-39. 3 McAlindon T, et al. Glucosamine and Chondroitin for Treatment of Osteoarthritis. JAMA 2000;283:1469-75. 4 Leeb B, et al. A meta-analysis of chondroitin sulfate in the treatment of osteoarthritis. J Rheumatol 2000;27:205-211. --- End forwarded message --- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2002 Report Share Posted April 12, 2002 In a message dated 04/04/02 13:24:12 Pacific Daylight Time, joguest writes: > What Is So Important About Glucosamine and Chondroitin JoAnn, was it you who informed me that I could not take Glucosomine with my health problems? I lost a few articles unfortunately and believe that one was among them. Thanks a lot. Marianne Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2002 Report Share Posted April 12, 2002 The info on Glucosamine and Chondrotin is full of confusion. I've heard that Chondroitin is of no value against the health problems for which it's commonly used. The same source said that it was the Glucosamine that had value. Recently, however, I read that Glucosamine is pure hype, and that the molecule is too large to be absorbed anyway. I didn't keep references for all of this. I wish I had. John P - <marianne2406 Friday, April 12, 2002 12:11 PM Re: Fwd: What is So Important about Glucosamine and Chondroitin? > In a message dated 04/04/02 13:24:12 Pacific Daylight Time, > joguest writes: > > > > What Is So Important About Glucosamine and Chondroitin > > JoAnn, was it you who informed me that I could not take Glucosomine with my > health problems? I lost a few articles unfortunately and believe that one > was among them. > Thanks a lot. > Marianne > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 14, 2002 Report Share Posted April 14, 2002 ---Good Evening Marianne-- If I remember correctly you were diagnosed with extreme arterial blockages, gallstones and high blood pressure. To my knowledge there are no contraindications concerning these particular health issues. Glucosamine sulfate and chondroitin have been helpful for those who are afflicted with arthritis and/or joint problems. You may email me privately if you wish to have this particular article resent. Cheers! JoAnn Guest joguest Friendsforhealthnaturally http://canceranswer.homestead.com/AIM.html marianne2406@a... wrote: > In a message dated 04/04/02 13:24:12 Pacific Daylight Time, > joguest@m... writes: > > > > What Is So Important About Glucosamine and Chondroitin > > JoAnn, was it you who informed me that I could not take Glucosomine with my > health problems? I lost a few articles unfortunately and believe that one > was among them. > Thanks a lot. > Marianne > > > Quote Link to comment Share on other sites More sharing options...
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