Influence of human obesity on the metabolic fate of dietary long- and medium-chain triacylglycerols.

[Guest guest]

Hi All,

 

Interesting paper showing that in over weight folks, long chain fatty acids are

not used so much for energy and are

instead stored as fat. However medium chain fatty acids (such as you get in

virgin coconut oil) are still burnt easily

for fuel and not stored as fat.

 

Thus for overweight folks, moving oil and fat intake away from veggie oils,

margarine, butter, animal fat with their

almost 100 % long chains to coconut oil and its 65 % medium and short chains

will allow these dietary calories to be

burnt for fuel and not stored as ever increasing fat.

 

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=9\

537605 & dopt=Abstract

Am J Clin Nutr 1998 Apr;67(4):595-601 Related Articles, Books, LinkOut

Influence of human obesity on the metabolic fate of dietary long- and

medium-chain triacylglycerols.

Binnert C, Pachiaudi C, Beylot M, Hans D, Vandermander J, Chantre P, Riou JP,

Laville M.

Groupement d'Interet Public Centre de Recherche en Nutrition Humaine de Lyon,

Hopital E Herriot, France.

binnert

 

The metabolic fate of an oral long-chain-triacylglycerol (LCT) load and of a

mixed oral LCT and

medium-chain-triacylglycerol (MCT) load was followed for 6 h in eight control

and eight obese subjects with normal

postabsorptive triacylglycerol concentrations.

 

Labeled triacylglycerol and indirect calorimetry were used.

 

Results showed that LCTs were less oxidized [burnt for fuel..gw] in obese than

in control subjects (3.2+/-0.5 compared

with 6.0+/-0.4 g, P < 0.01).

 

Moreover, the amount of LCT oxidized was negatively correlated with fat mass (r

= -0.77, P < 0.01). [the more stored fat

the less long chains are burnt..gw]

 

Appearance in plasma of dietary triacyglycerol-derived long-chain fatty acids

was blunted in obese subjects and it was

negatively related to fat mass (r = -0.84, P < 0.01) and positively to LCT

oxidation (r = 0.70, P < 0.01).

 

On the contrary, MCT oxidation was not altered in obese subjects compared with

control subjects.

 

Furthermore, the proportion of MCTs oxidized was higher in both groups compared

with LCTs (x+/-SEM: 57.5+/-2.6% compared

with 15.2+/-1.6%, P < 0.01, n = 16).

 

Our conclusion is that obesity is associated with a defect in the oxidation of

dietary LCTs probably related to an

excessive uptake by the adipose tissue of meal-derived long-chain fatty acids.

MCTs, the oxidation of which is not

altered in obesity, could therefore be of interest in the dietary treatment of

obesity.

 

PMID: 9537605 [PubMed - indexed for MEDLINE]

 

========================

Good Health & Long Life,

Greg Watson, http://optimalhealth.cia.com.au gowatson

USDA database (food breakdown) http://www.nal.usda.gov/fnic/foodcomp/

PubMed (research papers) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

DWIDP (nutrient analysis) http://www.walford.com/dwdemo/dw2b63demo.exe

Patch file for above http://www.walford.com/download/dwidp67u.exe

KIM (omega analysis) http://ods.od.nih.gov/eicosanoids/KIM_Install.exe

[Guest guest]

One might reasonably presume that periodic consumption of MCT's by the

obese would cause increaesed levels of fat burning proteins in the

mitochondria, and then enhance LCT burning modestly when the MCT's are

not around.

 

Anyone have info on people using coconut oil for weight loss? I

vaguely remember hearing something about this.

[Guest guest]

-

" andrewhallcutler " <AndyCutler

 

Friday, January 25, 2002 4:04 PM

Re: Influence of human obesity on the metabolic fate of

dietary long- and medium-chain

triacylglycerols.

 

 

> One might reasonably presume that periodic consumption of MCT's by the

> obese would cause increaesed levels of fat burning proteins in the

> mitochondria, and then enhance LCT burning modestly when the MCT's are

> not around.

 

Hi Andrew,

 

It does exactly that and by replacing carb cals, the MCTs in VCNO results in

lower post meal glucose and insulin levels.

A bonus for diabetics as less insulin is needed.

========================

Optimal Health & Longevity,

Greg Watson,

http://optimalhealth.cia.com.au

Optimal_Health_and_Longevity