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Effect of the fat composition of a single meal on the composition and cytotoxic potencies of lipolytically-releasable free fatty acids in postprandial plasma.

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Hi Greg,

 

>>>>Note the conclusions:

" Further study showed that all long-chain monounsaturated FFA and

polyunsaturated FFA, but not saturated FFA,

incorporated into lipoproteins (LDL) were cytotoxic to cultured MPM.

 

***Wow! One study after another demonstrating the same point. Keep 'em

coming! I've saved most of the abstracts you posted in regard to PUFAs and

lipid peroxidation and posted most of them to my dog and cat health list -

in hopes that people might think first before pumping their pets full of

fish oil without at least considering some of negative aspects of high PUFA

diets first. I think most folks are still operating under the false notion

that saturated fats clog arteries and fish oil is the miracle of the decade

having only healthy benefits with no side effects. My personal feeling is

that high PUFA diets may be even more deleterious to carnivores (dogs and

cats) as their evolutionary diets are based solely or nearly completely on

animal flesh and bone, unlike omnivorous humans who derived some of their

PUFA intake from plants.

 

Thanks again for sharing all these studies - I think fatty the acid

composition of our diets is one of the keys to good health -so the more

informed we are, the healthier we will be!

 

Suze Fisher

Web Design & Development

http://www.suscom-maine.net/~cfisher/

cfisher

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" Suze Fisher " <cfisher

 

Monday, January 21, 2002 11:51 PM

Effect of the fat composition of a single meal on the

composition and cytotoxic potencies of

lipolytically-releasable free fatty acids in postprandial plasma.

 

 

> Thanks again for sharing all these studies - I think fatty the acid

> composition of our diets is one of the keys to good health -so the more

> informed we are, the healthier we will be!

 

Hi Suze Fisher,

 

We do need the Omega 3's, just not too much. The big problem is elimination

Omega 6 as we get all we need from veggies.

========================

Good Health & Long Life,

Greg Watson, http://optimalhealth.cia.com.au gowatson

USDA database (food breakdown) http://www.nal.usda.gov/fnic/foodcomp/

PubMed (research papers) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

DWIDP (nutrient analysis) http://www.walford.com/dwdemo/dw2b63demo.exe

Patch file for above http://www.walford.com/download/dwidp67u.exe

KIM (omega analysis) http://ods.od.nih.gov/eicosanoids/KIM_Install.exe

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So Greg are you saying that all these women taking EPO for PMT are doing

themselves a disservice? Isn't EPO an Omega 6?

 

Tracy]

 

-

" Greg Watson " <gowatson

 

Tuesday, 22 January 2002 16:34

Re: Effect of the fat composition of a single meal on

the composition and cytotoxic potencies of lipolytically-releasable free

fatty acids in postprandial plasma.

 

 

> -

> " Suze Fisher " <cfisher

>

> Monday, January 21, 2002 11:51 PM

> Effect of the fat composition of a single meal on

the composition and cytotoxic potencies of

> lipolytically-releasable free fatty acids in postprandial plasma.

>

>

> > Thanks again for sharing all these studies - I think fatty the acid

> > composition of our diets is one of the keys to good health -so the more

> > informed we are, the healthier we will be!

>

> Hi Suze Fisher,

>

> We do need the Omega 3's, just not too much. The big problem is

elimination Omega 6 as we get all we need from veggies.

> ========================

> Good Health & Long Life,

> Greg Watson, http://optimalhealth.cia.com.au gowatson

> USDA database (food breakdown) http://www.nal.usda.gov/fnic/foodcomp/

> PubMed (research papers) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

> DWIDP (nutrient analysis) http://www.walford.com/dwdemo/dw2b63demo.exe

> Patch file for above http://www.walford.com/download/dwidp67u.exe

> KIM (omega analysis)

http://ods.od.nih.gov/eicosanoids/KIM_Install.exe

>

>

>

>

> Getting well is done one step at a time, day by day, building health

> and well being.

>

> To learn more about the Gettingwell group,

> Subscription and list archives are at:

> Gettingwell

>

>

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" Nick Grant " <nwgrant

 

Tuesday, January 22, 2002 2:52 PM

Re: Effect of the fat composition of a single meal on the

composition and cytotoxic potencies of

lipolytically-releasable free fatty acids in postprandial plasma.

 

 

> So Greg are you saying that all these women taking EPO for PMT are doing

> themselves a disservice? Isn't EPO an Omega 6?

 

Hi Tracy,

 

That they need this is a clear sign of Omega 3 EPA deficiency.

 

In the body EPO (actually Omega 6 GLA) is rapidly elongated to Omega 6 DGLA

(which is the active form). Then depending

on how much EPA is in the blood and the cell membranes, it may be further

desaturated (a double bond is added) into

Omega 6 AA (the mostly undesired form).

 

The more EPA in the diet, the less DGLA is converted into AA and thus DGLA level

should increase and also the PGE1

eicosanoid the cells make from it. It is increased levels of PGE1, PGE3 (made

from EPA) and less PGE2 (made from AA)

that we need.

 

Omega 6 LA (18:2w6) << Only from diet

V

Desaturation by the enzyme D6D

V

Omega 6 GLA (18:3w6) << Also from EPO

V

Elongation by the enzyme elongase

V

Omega 6 DGLA (20:2w6) >> PGE1 eicosanoid (good guy)

V

Desaturation by D5D (inhibited by increasing Omega 3 EPA)

V

Omega 6 AA (20:4w6) << Also from the diet (eggs, red meat, etc) >>

PGE2 eicosanoid (bad guy in excess)

 

The inhibition of the DGLA to AA conversion step by increasing EPA levels is

critical to eicosanoid balancing. However

to much Omega 6 LA in the diet and nothing can control the downward cascade of

Omega 6 LA into excessive Omega 6 A and

then excessive PGE2 and a very proinflammatory body. This is why in Omega

balancing, reducing Omega 6 LA intake to less

than 7 g is so important.

========================

Good Health & Long Life,

Greg Watson, http://optimalhealth.cia.com.au gowatson

USDA database (food breakdown) http://www.nal.usda.gov/fnic/foodcomp/

PubMed (research papers) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

DWIDP (nutrient analysis) http://www.walford.com/dwdemo/dw2b63demo.exe

Patch file for above http://www.walford.com/download/dwidp67u.exe

KIM (omega analysis) http://ods.od.nih.gov/eicosanoids/KIM_Install.exe

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Gettingwell, " Suze Fisher " <cfisher@b...> wrote:

> Hi Greg,

My personal feeling is

> that high PUFA diets may be even more deleterious to carnivores

(dogs and

> cats) as their evolutionary diets are based solely or nearly

completely on

> animal flesh and bone, unlike omnivorous humans who derived some of

their

> PUFA intake from plants.

>

 

 

Don't cats enjoy fish? I've never seen one that doesn't.

 

Roman

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>>>>>Don't cats enjoy fish? I've never seen one that doesn't.

 

 

 

 

 

Hi Roman,

yes, cats love fish, but there is no nutritional value in it and deep sea

fish contains mercury.

Though Juliette De Bairacli Levy does say that fresh sardines are okay.

 

Regards, Dorothy.

 

^..^ ^..^ ^..^ ^..^ ^..^ ^..^ ^..^ ^..^ ^..^ ^..^

 

Oh no!!!! Not tuna! Tuna causes a miserable and painful ailment in cats

called steatitis.

 

Here are some snips from previous posts regarding this problem:

Please, under no circumstances, feed you kitty tuna. Cats easily become

'tuna junkies' as the oil is very addicting. Tuna is considered a cat

allergen and can cause all sorts of illnesses - epilepsy, asthma,

hyperactivity and skin troubles.

 

It also causes heavy metal intoxication with such high amounts of mercury

that leads to chronic UTIs, liver, kidney and pancreatic damage. Tuna

destroys the cat's vitamin E stores and can also cause a muscular

dystrophy-like ailment called steatitis. If you must feed tuna, supplement

with E daily (even so - Es basically ineffective).

The heavy metal poisoning is also a problem for us lowly humans as well.

The fact that it's in aluminium cans is dangerous, too.

 

Tuna can actually be fatal to cats - as fatal as chocolate (oxalic acid in

chocolate prevents calcium absorption in dogs.

In cats it's the theobromine that's fatal). First, they become 'hooked' on

the strong flavor; Second, there's a high amount of polyunsaturated fat (the

'oil' I refer to)in tuna and a cat's system cannot metabolise it.

 

If it is packed in a vegetable oil (as in some commercial pet foods - great

tuna parts as well) this adds the additional danger of destroying the

vitamin E in the system, causing steatitis (a muscular dystrophy-type of

ailment). This ailment results in the cat's nerve endings becoming

supersensitive and the animal experiences pain whenever touched or held.

Actually, supplementing w/vit. E isn't good enough. Third, tuna does contain

high amounts of mercury and is systemically poisonous due to heavy metal

intoxication.

 

Steatitis or Yellow Fat Disease is found primarily in cats and fur-bearing

animals (Minks). It is characterized by a marked inflammation of adipose

tissue and the deposition of 'ceroid' (wax) pigment in the interstices

(small gaps) of the adipose (fat) tissue.

 

Etiology: It is believed that an overabundance of unsaturated fatty acids in

the food, together with a deficiency of vitamin E, results in the deposition

of the pigment in the fat. Most naturally occurring and experimentally

produced cases have occurred in animals that have had fish, or fish

by-products, as all or part of the diet; fish oil may be the primary agent.

Clinical Findings and Diagnosis: Affected cats are frequently plump and well

fed, usually young, and may be of either sex. They show loss of agility and

general unwillingness to move.

 

Resentment is exhibited on palpation of the back and abdomen. In the

advanced cases, even a light touch will cause pain.

Fever is a constant finding and anorexia may be present. (I won't go into

the findings regarding mink unless there are some owners on the list that

wish this info).

 

The typical laboratory finding is an elevated leukocyte count, with

neutrophilia (high white blood cell count) and sometimes eosinophilia

(abnormally large number of eosinophils-red staining white blood cells-in

the circulating blood). Biopsy of the subcut. fat shows it to be yellowish

brown, with a nodular or granular appearance. Microscopic examination

reveals severe inflammatory changes and associated ceroid pigment.

Treatment: Elimination of the offending food from the diet is imperative.

The administration of vitamin E, in the form of a-tocopherol, at least 30 mg

daily for cats, or 15 mg daily for mink, is necessary. Antibiotics are of

doubtful value, in spite of the fever and leukocytosis. Administration of

fluids is not advisable unless dehydration exists and the animal should be

handled as little as possible.

 

Basically - a cat and mink ailment that is only caused by fish oil. I see

nothing in my veterinary texts regarding dogs or other animals getting this

problem.

 

Rev. Debra L. Moore, D.N.

Doctor of Naturology

RevHerbDoc

 

Faithful friends never leave us...they just run ahead to wait for us in a

happier place. - My beloved Leo 8/92-9/98 & the rest of my lovies waiting

patiently for me.

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You haven't met my cat then? He hates fish!

 

Oops here he comes now - after his meal of dried food - what is one to do?

 

Tracy

 

 

> >>>>>Don't cats enjoy fish? I've never seen one that doesn't.

>

>

> >

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" r_rom " <r_rom

 

Tuesday, January 22, 2002 10:29 PM

Re: Effect of the fat composition of a single meal on the

composition and cytotoxic potencies of

lipolytically-releasable free fatty acids in postprandial plasma.

 

 

> Gettingwell, " Suze Fisher " <cfisher@b...> wrote:

> > Hi Greg,

> My personal feeling is

> > that high PUFA diets may be even more deleterious to carnivores

> (dogs and

> > cats) as their evolutionary diets are based solely or nearly

> completely on

> > animal flesh and bone, unlike omnivorous humans who derived some of

> their

> > PUFA intake from plants.

 

> Don't cats enjoy fish? I've never seen one that doesn't.

 

Hi Roman,

 

Fish yes, Omega 6 oils no.

========================

Good Health & Long Life,

Greg Watson, http://optimalhealth.cia.com.au gowatson

USDA database (food breakdown) http://www.nal.usda.gov/fnic/foodcomp/

PubMed (research papers) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

DWIDP (nutrient analysis) http://www.walford.com/dwdemo/dw2b63demo.exe

Patch file for above http://www.walford.com/download/dwidp67u.exe

KIM (omega analysis) http://ods.od.nih.gov/eicosanoids/KIM_Install.exe

Link to comment
Share on other sites

You could always throw the dry food out so your cat can't smell it,

then feed BARF diet. I expect after one or at most two days of hunger

strike, your cat will be eating the good stuff.

 

Alobar

 

 

-

" Nick Grant " <nwgrant

 

Tuesday, January 22, 2002 4:20 PM

Re: Effect of the fat composition of a single meal on

the composition and cytotoxic potencies of lipolytically-releasable free

fatty acids in postprandial plasma.

 

 

> You haven't met my cat then? He hates fish!

>

> Oops here he comes now - after his meal of dried food - what is one to do?

>

> Tracy

>

>

> > >>>>>Don't cats enjoy fish? I've never seen one that doesn't.

> >

> >

> > >

>

>

>

>

> Getting well is done one step at a time, day by day, building health

> and well being.

>

> To learn more about the Gettingwell group,

> Subscription and list archives are at:

> Gettingwell

>

>

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So what is this BARF? I am sorry - I didn't take a lot of notice of it -

since most things are out of our country, and expensive - but you have got

me curious now!

 

Tracy

 

-

" Alobar " <alobar

 

Wednesday, 23 January 2002 17:09

Re: Effect of the fat composition of a single meal on

the composition and cytotoxic potencies of lipolytically-releasable free

fatty acids in postprandial plasma.

 

 

> You could always throw the dry food out so your cat can't smell

it,

> then feed BARF diet. I expect after one or at most two days of hunger

> strike, your cat will be eating the good stuff.

>

> Alobar

>

>

> -

> " Nick Grant " <nwgrant

>

> Tuesday, January 22, 2002 4:20 PM

> Re: Effect of the fat composition of a single meal

on

> the composition and cytotoxic potencies of lipolytically-releasable free

> fatty acids in postprandial plasma.

>

>

> > You haven't met my cat then? He hates fish!

> >

> > Oops here he comes now - after his meal of dried food - what is one to

do?

> >

> > Tracy

> >

> >

> > > >>>>>Don't cats enjoy fish? I've never seen one that doesn't.

> > >

> > >

> > > >

> >

> >

> >

> >

> > Getting well is done one step at a time, day by day, building health

> > and well being.

> >

> > To learn more about the Gettingwell group,

> > Subscription and list archives are at:

> > Gettingwell

> >

> >

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