Guest guest Posted November 17, 2008 Report Share Posted November 17, 2008 Thanks dear viviane Regards Dr.JN Sharma On 11/17/08, Viviane Lerner <vivlerner wrote: > http://www.NaturalNews.com/z024828.html > Cancer Drugs Make Tumors Grow > by Sherry Baker (see all articles by this author) > > > (NaturalNews) Drugs like Avastin that are used to treat some cancers > are supposed to work by blocking a vessel growth-promoting protein > called vascular endothelial growth factor, or VEGF. With VEGF held in > check, researchers have assumed tumors wouldn't generate blood > vessels and that should keep malignancies from growing. In a sense, > the cancerous growths would be " starved " . But new research just > published in the journal Nature shows this isn't true. Instead of > weakening blood vessels so they won't " feed " malignant tumors, these > cancer treatments, known as anti-angiogenesis drugs, actually > normalize and strengthen blood vessels -- and that means they can > spur tumors to grow larger. > > For their study, researchers at the Moores Cancer Center at the > University of California, San Diego (UCSD) in La Jolla, replicated > the action of anti-angiogenesis drugs by genetically decreasing VEGF > levels in mouse tumors and inflammatory cells in several types of > cancers, including pancreatic cancer. The research team, headed by > David Cheresh, Ph.D., professor and vice chair of pathology at UCSD, > also used drugs to inhibit VEGF receptor activity. The results? In > every single instance, blood vessels were not weakened but, instead, > were made normal again. And in some cases, tumors increased in size.. > > In a prepared statement for the press, Dr. Cherish said: " We've > discovered that when anti-angiogenesis drugs are used to lower the > level of VEGF within a tumor, it's not so much a reduction in the > endothelial cells and losing blood vessels as it is an activation of > the tumor blood vessels supporting cells. It appears that the drugs, > in shutting down VEGF activity, are actively maturing blood vessels, > causing them to become stable and more normal, as opposed to reducing > blood vessels. " > > Although the findings of this study might sound like a death knell > for drugs like Avastin, Dr. Cheresh claims the fact anti-angiogenesis > drugs can increase tumor size and give them stronger blood vessels > could be a good thing. According to his press statement, he suggests > chemotherapy drugs may be able to get to cancer tumors more directly > through the stronger blood vessels created by the anti-angiogenesis > drugs. " We have to test available regimens and perhaps restructure > the way that we give drugs, " he said. " We may be giving the right > drugs, but we may not be giving them in the right order. We're just > beginning to understand how it works. " > > That could be seen a huge understatement. After all, Dr. Cheresh's > own research shows the supposedly cancer fighting anti-angiogenesis > drugs appear to do exactly the opposite of what scientists thought > they did. > > Dr. Cheresh also points out in his media statement that the results > of the Nature study demonstrate how a specific host's response to > cancer is critical in terms of susceptibility to therapy. " It's not > just about the therapy, but also what the host does in response to > the cancer that makes a difference whether a tumor lives or dies, and > if it's susceptible to a drug or not. We can change the host response > to the cancer, " he stated. > > While Dr. Cheresh is talking about using drugs to influence how the > host responds to cancer, natural health advocates have pointed out > for decades that strengthening the body's own defense system and > avoiding cancer-promoting and potentially health-weakening toxins, > foods and behaviors can help keep cancer at bay. Mainstream medicine > appears to be recognizing the efficacy of this strategy more and > more, too. > > For example, a new review sponsored by the American Cancer Society > just published in CA: Cancer Journal for Clinicians studied potential > pharmaceutical, dietary, surgical, and other approaches to reducing > the risk of breast cancer . The conclusions show that risk reduction > strategies should focus primarily on lifestyle factors -- > specifically, eating a healthy diet, drinking alcohol moderately or > not at all, and maintaining a healthy weight. In other words, > natural, common sense healthy living that strengthen the " host " > appear to be the best ways to prevent cancer in the first place. > > > About the author > Sherry Baker is a widely published writer whose work has appeared in > Newsweek, Health, the Atlanta Journal and Constitution, Yoga Journal, > Optometry, Atlanta, Arthritis Today, Natural Healing Newsletter, > OMNI, UCLA's " Healthy Years " newsletter, Mount Sinai School of > Medicine's " Focus on Health Aging " newsletter, the Cleveland Clinic's > " Men's Health Advisor " newsletter and many others. > > > ===== > > In accordance with Title 17 U.S.C. Section 107, this material is > distributed without profit to those who have expressed a prior > interest in receiving the included information for research and > educational purposes. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 18, 2008 Report Share Posted November 18, 2008 Original sender's name: Dr. Jagnarain Sharma Original sender's address: jagnarain.sharma Thanks dear viviane Regards Dr.JN Sharma On 11/17/08, Viviane Lerner < vivlerner wrote: http://www.NaturalNews.com/z024828.html Cancer Drugs Make Tumors Grow by Sherry Baker (see all articles by this author) (NaturalNews) Drugs like Avastin that are used to treat some cancers are supposed to work by blocking a vessel growth-promoting protein called vascular endothelial growth factor, or VEGF. With VEGF held in check, researchers have assumed tumors wouldn't generate blood vessels and that should keep malignancies from growing. In a sense, the cancerous growths would be "starved". But new research just published in the journal Nature shows this isn't true. Instead of weakening blood vessels so they won't "feed" malignant tumors, these cancer treatments, known as anti-angiogenesis drugs, actually normalize and strengthen blood vessels -- and that means they can spur tumors to grow larger. For their study, researchers at the Moores Cancer Center at the University of California, San Diego (UCSD) in La Jolla, replicated the action of anti-angiogenesis drugs by genetically decreasing VEGF levels in mouse tumors and inflammatory cells in several types of cancers, including pancreatic cancer. The research team, headed by David Cheresh, Ph.D., professor and vice chair of pathology at UCSD, also used drugs to inhibit VEGF receptor activity. The results? In every single instance, blood vessels were not weakened but, instead, were made normal again. And in some cases, tumors increased in size.. In a prepared statement for the press, Dr. Cherish said: "We've discovered that when anti-angiogenesis drugs are used to lower the level of VEGF within a tumor, it's not so much a reduction in the endothelial cells and losing blood vessels as it is an activation of the tumor blood vessels supporting cells. It appears that the drugs, in shutting down VEGF activity, are actively maturing blood vessels, causing them to become stable and more normal, as opposed to reducing blood vessels." Although the findings of this study might sound like a death knell for drugs like Avastin, Dr. Cheresh claims the fact anti-angiogenesis drugs can increase tumor size and give them stronger blood vessels could be a good thing. According to his press statement, he suggests chemotherapy drugs may be able to get to cancer tumors more directly through the stronger blood vessels created by the anti-angiogenesis drugs. "We have to test available regimens and perhaps restructure the way that we give drugs," he said. "We may be giving the right drugs, but we may not be giving them in the right order. We're just beginning to understand how it works." That could be seen a huge understatement. After all, Dr. Cheresh's own research shows the supposedly cancer fighting anti-angiogenesis drugs appear to do exactly the opposite of what scientists thought they did. Dr. Cheresh also points out in his media statement that the results of the Nature study demonstrate how a specific host's response to cancer is critical in terms of susceptibility to therapy. "It's not just about the therapy, but also what the host does in response to the cancer that makes a difference whether a tumor lives or dies, and if it's susceptible to a drug or not. We can change the host response to the cancer," he stated. While Dr. Cheresh is talking about using drugs to influence how the host responds to cancer, natural health advocates have pointed out for decades that strengthening the body's own defense system and avoiding cancer-promoting and potentially health-weakening toxins, foods and behaviors can help keep cancer at bay. Mainstream medicine appears to be recognizing the efficacy of this strategy more and more, too. For example, a new review sponsored by the American Cancer Society just published in CA: Cancer Journal for Clinicians studied potential pharmaceutical, dietary, surgical, and other approaches to reducing the risk of breast cancer . The conclusions show that risk reduction strategies should focus primarily on lifestyle factors -- specifically, eating a healthy diet, drinking alcohol moderately or not at all, and maintaining a healthy weight. In other words, natural, common sense healthy living that strengthen the "host" appear to be the best ways to prevent cancer in the first place. About the author Sherry Baker is a widely published writer whose work has appeared in Newsweek, Health, the Atlanta Journal and Constitution, Yoga Journal, Optometry, Atlanta, Arthritis Today, Natural Healing Newsletter, OMNI, UCLA's "Healthy Years" newsletter, Mount Sinai School of Medicine's "Focus on Health Aging" newsletter, the Cleveland Clinic's "Men's Health Advisor" newsletter and many others. «¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤«¤»¥«¤»§«¤»¥«¤»§«¤» § - PULSE ON 21st CENTURY ALTERNATIVE MEDICINE! § Subscribe send email to: - «¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤«¤»¥«¤»§«¤»¥«¤»§«¤» Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.