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OF MICE AND MEN

Man not needed to make baby?

Researchers grow sperm from stem cells, fertilize eggs

http://www.worldnetdaily.com/news/article.asp?ARTICLE_ID=36067

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Posted: December 10, 2003

3:42 p.m. Eastern

 

 

 

© 2003 WorldNetDaily.com

 

Scientists have moved a step closer to creating life in a petri dish –

without the use of a man.

 

Researchers at Harvard Medical School say they've succeeded in turning mouse

embryonic stem cells into primitive sperm cells, and then used the sperm

cells to fertilize eggs.

 

According to the British journal Nature, George Daley and his colleagues

took tail-less precursors of sperm cells, cultured them for a week in a dish

of retinoic acid (which caused them to multiply), and ejected them into

unfertilized eggs. The eggs developed into embryos.

 

The technique is being touted as a new tool to help the emerging branch of

gene therapy enable fathers in the future to sire children free of genetic

flaws.

 

The scientists did not take their experiment as far as allowing the embryos

to develop into live-born mice, but are now studying whether such a feat is

possible.

 

Dr. John Gearhart, a Johns Hopkins University stem-cell researcher,

cautioned that it is not clear whether the fertilized mouse eggs would have

developed into normal embryos, reports the Associated Press.

 

The study involved embryonic germ cells, which appear in early embryos and

mature into either sperm or egg cells.

 

Daley said research will allow scientists to study closely the development

of germ cells, considered the " master " material being explored as the

replacement-organ tissue of the future.

 

" Germ cells are in some sense the immortal cells of our species. They're

really endowed and given the responsibility for perpetuating the species, "

Daley said.

 

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