Guest guest Posted October 28, 2000 Report Share Posted October 28, 2000 Comfrey - Symphytum officinale Therapeutic Actions: * Anti-inflammatory * Antimutagenic activity, increases survival times of mice bearing spontaneous tumors and decreased tumor growth * Antipsoriatic * Aqueous extract stimulates the release of a prostaglandin-like material from gastric mucosa * Breaks down red blood cells, therefore used for bruises * Demulcent mucilage makes a powerful healing agent in mucosal ulcers * Stimulates IL-1 and INF production in vitro * Stimulates T and B cell activity * Soothing and wound healing due to allantoin * Stimulates cell proliferation that promotes the growth of bone, cartilage and connective tissue Clinical Indications: * Aphthous stomatitis * Bronchitis * Eczema * Peptic ulcer disease * Psoriasis * Ulcerative colitis * Chronic varicose ulcers * External ulcers, use as a compress or poultice * Fractures, use as a compress or poultice Contraindications: * Extended use longer than 4 weeks * Liver disease due to alkaloid hepatotoxicity * Nursing mothers due to pyrrolizidine alkaloids * Pregnancy due to pyrrolizidine alkaloid Drug/Nutrient Interaction: * Limited data Chemical Constituents: * Allantoin * Asparagine * Carotene * Choline * Muscilage, composed of a polysaccharide containing glucose and fructose * Phenolic acids: Caffeic acid, Chlorogenic acid, Lithospermic acid, Rosmarinic acid * Pyrrolizidine alkaloids (hepatotoxic in aminals but these alkaloids are usually not found in commercial samples): Echimidine, Lycopsamine, Symlandine, Symphytine * Protein * Steroidal saponins * Tannins * Triterpenes * Vitamin B12 * Zinc Toxicity: * Do not use excessively Quote Link to comment Share on other sites More sharing options...
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