Obesity and bowel bacteria link

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Obesity-Causing Bacteria -- and the Cure

Posted by: "Debby Padilla-Hudson" debbypadilla debbypadilla

Tue Dec 8, 2009 9:33 am (PST)

Great story.. my comments in parenthesis. .. Obesity-Causing Bacteria -- and the CureThere’s little doubt that diet and lifestyle choices play a major role in the obesity epidemic in America. But investigators have recently uncovered another intriguing theory about the causes of obesity -- it turns out that obese people have different gut bacteria. Though this is not the sole factor, experts now are delving further to learn all they can about what role these tiny microbes play in this big threat to our health.Obese People Host a Different Mix of Bacteria than Lean IndividualsThe human body is host to trillions of microbes (bacteria), some that support our health and others that threaten it, notes Daily Health News contributing editor Andrew Rubman, ND. There is lots of research underway on the connection between obesity and

gut bacteria, but early findings already demonstrate that different people are host to different colonies of microorganisms in their guts and these variations affect weight as well as health. Some of the differences may be genetic, others are a result of our unique dietary environments. Several studies in particular highlight the connection.. .* At Washington University School of Medicine in St. Louis, Missouri, scientists found that the intestinal tracts of obese and thin people have different ratios of two types of bacteria that normally predominate in the human gut -- Firmicutes and Bacteroidetes. Obese individuals had higher percentages of Firmicutes and lower percentages of Bacteroidetes bacteria, while the lean group had roughly the opposite balance. After the obese individuals lost weight by following a low-calorie diet for one year, the ratio of these two types of bacteria in the obese individuals became more like that of the lean

group.* In another experiment, also at Washington University, scientists bred mice to be free of intestinal flora, then fed them gut bacteria taken from obese mice -- and they got fat. In contrast, flora-free mice given gut bacteria from skinny mice gained little weight. The researchers concluded that differences in gut flora may contribute to obesity. The Ecology of the GutWhile there is more to learn about the influence of gut ecology on weight, keeping the bacteria of your digestive system in proper balance is essential to maintaining optimal health, says Dr. Rubman. He told me it is well-documented that problems in the large intestine -- the hub of the body’s immune system -- quickly lead to problems elsewhere in the body. Beneficial bacteria help your body break down food and absorb nutrients, so it makes sense that having more healthful bacteria helps digestion.Poor diet, emotional stress or physical disease,

along with other factors, disturb the natural balance, allowing harmful bacteria to proliferate, so it is harder for good bacteria to protect the mucosal walls of the intestines. When these become more permeable, toxins leak out, challenging immunity and causing inflammation locally and elsewhere in the body.Our bodies are programmed to protect us from negative external influences and challenges, so threats (such as inflammation) may lead to an increase in energy storage (i.e., calories) to meet the challenge. If this mistaken attempt at self-protection persists, the ecology of the gut adjusts to favor bacteria that are more proficient at extracting calories from food.Over time, these calorie-hungry microbes contribute to weight gain, making it even harder for overweight people to shed unwanted pounds -- an all-too-common complaint. So, the theory goes, people who are already overweight can eat the same meals as lean people, but

they’ll absorb more calories. Harmful bacteria also slow the passage of food through the digestive tract, and the more time food spends in the body, the more calories you absorb from it.Fortunately, there are steps that you can take to encourage and restore a proper microbial balance in your gut. One way to optimize your balance of intestinal bacteria is to follow a probiotic diet, which will rev up your metabolism and spur weight loss, according to Joseph Brasco, MD, a gastroenterologist in private practice in Huntsville, Alabama, and coauthor of Restoring Your Digestive Health and the upcoming Probiotic Diet.Especially if you are doing everything right -- eating nutritiously, watching portion size and exercising regularly -- if you still cannot lose weight, the problem may be related to an imbalance of gut flora.To tip the scales toward weight loss, Dr. Brasco recommends these simple strategies:* Consume more fresh

fruits (veggies are a better choice) and vegetables and fewer processed foods. What you don’t eat is just as important as what you do, Dr. Brasco emphasizes. Fresh produce encourages the production of friendly microbes. Fiber in fruits and vegetables (especially the skin) helps speed food through the digestive tract. This improves the health of the intestinal lining by nurturing the right bacteria. Toxins don’t linger as long, so they do less damage. In contrast, processed foods, such as breads, doughnuts and cookies, are loaded with starch and simple sugars -- exactly what harmful bacteria thrive upon. (Don't forget nutritious protein and fats nourish the body and also don't feed the bad guys).* Eat fermented foods every day. To restore proper gut balance, regularly eat yogurt (dairy-free fermented foods are a much better choice) with active cultures, chutneys, unpasteurized sauerkraut, pickles, kimchi, kefir and miso. Try a new type each

day -- for example, snack on yogurt... add chutney to a dinner stew... slice some pickles into your salad. Beneficial organisms associated with fermentation colonize the gut and discourage the growth of harmful bacteria.* Take a daily probiotic supplement. When diet and exercise still fail to generate weight loss, Dr. Brasco has seen patients get good results with probiotics. His favorite brands: Garden of Life’s Primal Defense Ultra and Align (Procter & Gamble), both available at health-food stores and online, and HLC (Pharmax), available through your health care provider. * If a probiotic supplement makes you gassy or bloated, try taking it on an empty stomach, suggests Dr. Brasco. Most doctors advise patients to take probiotics with food, but he says trying them away from meals sometimes helps this problem. Other solutions include taking a probiotic supplement every other day to start and working your way up to daily... or you

could try a different product based on a different mix of bacteria, since there are a variety available. Ask your doctor for help in identifying the right mix for you.Source(s):Andrew Rubman, ND, director, Southbury Clinic for Traditional Medicines, Southbury, Connecticut.Joseph Brasco, MD, Center for Colon and Digestive Disease, Huntsville, Alabama. Dr. Brasco is coauthor of Restoring Your Digestive Health (Kensington Press) and the upcoming Probiotic Diet (the working title of the book, to be published by Strange).