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HSI e-Alert - Four Words Health Sciences Institute e-Alert

 

 

 

 

 

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April 26, 2006

Why am I getting this?

 

 

 

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Dear Reader,

 

I've got some Alzheimer's news. So...do you want to start with the good news, or the bad news?

Let's start with the good news: According to a new study, a combination of two vitamins may help many people reduce their risk of Alzheimer's disease (AD).

And now for the bad news: The study also found that to reduce the risk of Alzheimer's in people who are at high risk of developing the disease, the two vitamins need to be combined with ibuprofen.

Four words come to mind: Not a good idea.

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Turning down the heat -----------

 

Research shows that people with a gene variant known as APOE-4 are more likely to develop clumps of protein called amyloid plaques. These plaques are believed to be responsible for an inflammatory response that plays a key role in the brain cell death that causes Alzheimer's disease.

In a new study led by Dr. Majid Fotuhi of Johns Hopkins University, researchers monitored a cohort of 5,000 elderly subjects for eight years, taking special note of their intake of ibuprofen (a non-steroidal anti-inflammatory drug) and vitamins C and E. Fotuhi's team found that subjects at low risk of AD (those who did not have the APOE-4 variant) reduced their risk even further with a high intake of the two vitamins.

Subjects with the APOE-4 variant who took ibuprofen on a regular basis and had a high intake of C and E showed no decline in cognitive function over eight years. Memory decline was more likely among the APOE subjects who had a high intake of only one of the agents tested.

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What to leave out -----------

 

Dr. Fotuhi's study was presented at the recent annual meeting of the American Academy of Neurology. The study hasn't been published yet, but Dr. Fotuhi explained to Reuters Health that the vitamins reduced inflammation while ibuprofen reduced the amyloid that causes inflammation.

With no published study to review, we can't know exactly how Dr. Fotuhi arrived at this conclusion about ibuprofen. But in his Reuters Health interview, Dr. Fotuhi also noted that consumers should be cautious with their ibuprofen intake, and I agree completely, given the drug's potential for contributing to liver and kidney impairment, and gastrointestinal conditions such as bleeding and ulcers.

But the Reuters article notes that Dr. Fotuhi is "so encouraged" by his findings that he's patented a supplement that contains vitamins C and E, a small amount of omega-3 fatty acids, and...ibuprofen. Dr. Fotuhi told Reuters that he recommends an ibuprofen dose "no higher than 100 milligrams per day." So I suppose we can assume that his C/E/omega-3/ibuprofen combo contains about 100 mg of the drug?

The question is: Should even a small amount of ibuprofen be taken every day to prevent Alzheimer's? I'll let another Johns Hopkins researcher answer that question.

In 1997, a Hopkins team conducted a 15-year study of more than 1,600 elderly subjects and found that frequent ibuprofen use may reduce AD risk by as much as 60 percent. But in an article published by the LA Times-Washington Post News Service, researchers stressed the damage that can be caused by constant use of the drug.

Dr. Claudia Kawas (lead author of the Hopkins study) told the New Service, "Ibuprofen can shut down your kidneys. That would be a terrible thing to do while trying to prevent something you might not get."

It's good to know that vitamins C and E may offer protection against one of the most dreaded diseases associated with aging. We'll thank Dr. Fotuhi for that welcome information...and leave it at that.

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To start receiving your own copy of the HSI e-Alert, visit:

http://www.hsibaltimore.com/ealerts/freecopy.html

Or forward this e-mail to a friend so they can sign-up to

receive their own copy of the HSI e-Alert.

 

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....and another thing

 

Hey diddle diddle The cat and the fiddle The camel jumped over the moon

That variation of the popular nursery rhyme might be what children from the Sahara to Mongolia sing, because a lot of them are drinking camel milk these days. According to the Food and Agriculture Organization (FAO) of the United Nations, nearly five and a half million metric tons of camel milk is consumed every year.

Apparently that's not enough to satisfy demand, but even so, there are plans afoot to increase production and distribute the milk throughout parts of Africa, Europe and even the Americas. FAO reps believe this market could expand to $10 billion per year.

It seems camels produce a very nutritious milk, containing plenty of iron, B vitamins, unsaturated fatty acids and three times more vitamin C than cow milk.

But some production problems will need to be ironed out before camel milk starts popping up at your local grocery store. For instance, at this point, most camel milk producers are nomads.

Another problem: Camels only yield about five liters of milk per day. But FAO dairy expert Anthony Bennett told NutraIngredients: "With improved feed, husbandry and veterinary care daily yields could rise to 20 liters."

I wonder if "improved feed, husbandry and veterinary care" is code for "growth hormones"?

According to Robert Cohen, the executive director of the Dairy Education Board, a century ago the average cow produced only one quart of milk per day. Growth hormones have helped take care of that low-yield problem by expanding udders to sizes that a 1906 dairy farmer might find hard to comprehend. A cow on a typical U.S. dairy farm in 2006 may yield as much as 15 GALLONS per day.

 

So if you think it's hard to find raw cow milk produced without hormones, antibiotics or pasteurization, just imagine how difficult it will be to find raw camel milk! Unless of course you happen to have a friend who's a North African nomad.

To Your Good Health,

 

Jenny Thompson

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To start receiving your own copy of the HSI e-Alert, visit:

http://www.hsibaltimore.com/ealerts/freecopy.html

Or forward this e-mail to a friend so they can sign-up to

receive their own copy of the HSI e-Alert.

 

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Tap into the minds of other health-conscious readers like yourself at the new HSI health forum: http://www.healthiertalk.com

 

Sources:

"Vitamins Plus Ibuprofen May Ward Off Alzheimer's" Karla Gale, Reuters Health, 4/7/06, reutershealth.com "Ibuprofen Sharply Reduces Alzheimer's but endangers Kidneys, Study Shows" LA Times-Washington Post News Service, 3/9/97, lubbockonline.com "Camel Milk: The Dairy Product of the Future" NutraIngredients, 4/19/06, nutraingredients.com "Holy Cow" Robert Cohen, Dairy Education Board, notmilk.com

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The e-Alert may not be posted on commercial sites without

written permission.

 

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**************************************************** To learn more about HSI, call (203) 699-4416 or visit, http://www1.youreletters.com/t/357007/2577399/297/0/

 

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