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Resveratrol's anti-cancer activity explained

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Frank <califpacific wrote:

alternative_medicine_forum From: Frank Thu, 2 Sep 2004 16:00:45 -0700 (PDT) Resveratrol's anti-cancer activity explainedhttp://www.swansonvitamins.com/include/newsletter/emailRU_090304/RUa1_090304.htmlResveratrol's anti-cancer activity explainedScientists have discovered a possible mechanism forthe anti-cancer activity of resveratrol, the compoundfound in red wine and thought to be responsible forthe drink’s widely reported health benefits.The findings, which were published on the onlineedition of the Journal of the European MolecularBiology Organization (EMBO), demonstrated that cancercells treated with resveratrol died because theybecame sensitive to a compound called Tumor NecrosisFactor alpha (TNFa).Marty Mayo,

assistant professor of biochemistry andmolecular genetics at the University of Virginia, andhis team reported that TNFa helps to starve cancercells by inhibiting the action of a key protein thatfeeds them. The protein, called nuclear factor-kappa B(NFKb), is found in the nucleus of all cells andactivates genes responsible for cell survival. Theresearchers found that resveratrol initiated areaction in the NFKb molecule that caused the cancercells to self-destruct in a process called apoptosis.“We used physiologically-relevant doses of resveratroland found dramatic effects on human cancer cells,”said Mayo. The researchers said the action of NFKb mayalso explain how resveratrol helps to controlatherosclerosis, heart disease, arthritis, andautoimmune disorders.Journal of the European Molecular Biology Organization23(12):2369-2380, 2004

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This I

find quite interesting. The only question I have is how much do you need

to consume at a given time. I am not a drinker at all so it would be

difficult for me. But, if it will kill the cancer cells, I am willing to

try it. Anyone have any info on how to take it?

Hugs,

Carolyn

 

Mentor " Wholeness & Healing " and " One For

Life " Communities

http://www.women-of-worth.org/communities.shtml

http://www.juiceplus.com/+cm90259

 

 

 

Kelly Wortkoetter

[kellykebby]

Friday,

September 03, 2004 11:36 AM

 

 

Resveratrol's anti-cancer activity explained

 

 

 

 

Frank

<califpacific wrote:

To:

alternative_medicine_forum

Frank

Thu, 2 Sep 2004 16:00:45 -0700 (PDT)

Resveratrol's anti-cancer activity

explained

 

http://www.swansonvitamins.com/include/newsletter/emailRU_090304/RUa1_090304.html

 

Resveratrol's anti-cancer activity explained

 

Scientists have discovered a possible mechanism for

the anti-cancer activity of resveratrol, the compound

found in red wine and thought to be responsible for

the drink’s widely reported health benefits.

 

The findings, which were published on the online

edition of the Journal of the European Molecular

Biology Organization (EMBO), demonstrated that cancer

cells treated with resveratrol died because they

became sensitive to a compound called Tumor Necrosis

Factor alpha (TNFa).

 

Marty Mayo, assistant professor of biochemistry and

molecular genetics at the University of Virginia, and

his team reported that TNFa helps to starve cancer

cells by inhibiting the action of a key protein that

feeds them. The protein, called nuclear factor-kappa B

(NFKb), is found in the nucleus of all cells and

activates genes responsible for cell survival. The

researchers found that resveratrol initiated a

reaction in the NFKb molecule that caused the cancer

cells to self-destruct in a process called apoptosis.

 

“We used physiologically-relevant doses of resveratrol

and found dramatic effects on human cancer cells,”

said Mayo. The researchers said the action of NFKb may

also explain how resveratrol helps to control

atherosclerosis, heart disease, arthritis, and

autoimmune disorders.

 

Journal of the European Molecular Biology Organization

23(12):2369-2380, 2004

 

 

 

 

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