prostate cancer and meat consumption

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Professor Antonio Avocado (vegscience.vegsource.org) Prostate cancer - Is it mainly because of the meat? June 10, 1999 at 19:15:04 PST Prostate cancer - Is it mainly because of the meat? CHARLOTTESVILLE, VIRGINIA. Prostate cancer is now the most commonly diagnosed cancer among American and European men. It is also common in Eastern countries, but the incidence of fatal, metastatic prostate cancer is much lower there. This suggests that some dietary or environmental factor is involved in determining whether prostate cancer spreads to other organs or not. Researchers at the University of Virginia Cancer Center believe they have uncovered an important clue to the puzzle. Their experiments have shown that arachidonic acid, an omega-6 fatty acid mainly found in meat and animal products, stimulates the growth of prostate cancer cells through the production of a metabolite, 5-HETE (5-hydroxyeicosatetraenoic acid). The researchers found that 5-HETE is essential for the survival of prostate cancer cells and that these cells are completely eradicated (in vitro) in a few hours by blocking the production of 5-HETE. They conclude that a high intake of dietary fats accelerates the progression of prostate cancer and that arachidonic acid is intimately involved in this process. They also suggest that drugs which inhibit the formation of 5-HETE may prove useful in the battle

against prostate cancer. Ghosh, Jagadananda and Myers, Charles E. Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. Proceedings of the National Academy of Sciences USA, Vol. 95, No. 22, October 27, 1998, pp. 13182-87 http://www.vegsource.com/talk/science/messages/326.ht

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