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California to Review Fluoride as a Carcinogen in water

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Proposition 65

Announcement of Chemicals Selected by OEHHA for Consideration for Listing

by the Carcinogen Identification Committee and Request for Relevant

Information on the Carcinogenic Hazards of These Chemicals

[10/15/09]

The California Environmental Protection Agency’s Office of Environmental

Health Hazard Assessment (OEHHA) is the lead agency for the implementation of

the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition

65). The Carcinogen Identification Committee (CIC) of OEHHA’s Science

Advisory

Board serves as the State’s qualified experts for rendering an opinion

whether a chemical has been clearly shown through scientifically valid testing

according to generally accepted principles to cause cancer. The chemicals

identified by the CIC are added to the Proposition 65 list, which must be

updated annually.

On _May 29, 2009, the CIC_

(http://www.oehha.ca.gov/prop65/public_meetings/cicagenda051509.html)

considered the priority ranking of 38 chemicals of

which they recommended that nine of the chemicals be placed in the High

priority category. OEHHA has initially selected five of the nine chemicals for

the CIC’s review for possible listing under Proposition 65 and is

initiating the development of hazard identification materials for these

chemicals.

[The remaining four chemicals will be the subject of a future public

notice or notices.] The five chemicals are listed in Table 1 below.

Table 1. Chemicals Selected for Preparation of Cancer Hazard

Identification Materials and Review for Possible Listing by the Carcinogen

Identification Committee

Chemical

CAS No.

3-Monochloropropane-1,2-diol

96-24-2

1,3-Dichloro-2-propanol

96-23-1

Fluoride and its salts

---

Diisononyl phthalate (DINP)

---

Perfluorooctanoic acid (PFOA) and its salts and transformation and

degradation precursors

---

These chemicals were selected using the procedure described in the document

entitled: “Process for Prioritizing Chemicals for Consideration under

Proposition 65 by the State’s Qualified Experts,†adopted in 2004, and

available on the Internet at _www.oehha.ca.gov_ (http://www.oehha.ca.gov/) .

OEHHA identified 38 chemicals through application of an epidemiology data

screen and an animal data screen, and a preliminary toxicological evaluation

of the available overall evidence of carcinogenicity, as outlined in the

2004 prioritization process. These 38 chemicals were _presented and

released for public comment on March 5, 2009_

(http://www.oehha.ca.gov/prop65/CRNR_notices/state_listing/prioritization_notice\

s/prior030509.html) , along with

a separate listing of the relevant studies identified for each chemical.

These materials were provided to the Committee and also made available on

OEHHA’s Web site at _www.oehha.ca.gov_ (http://www.oehha.ca.gov/) . The

Committee met to consider the materials for all 38 chemicals at a public

meeting on May 29, 2009. At this meeting, the Committee advised OEHHA by

majority vote that nine chemicals be given high priority consideration for

preparation of hazard identification materials. The five chemicals identified

in

Table 1 are a subset of the nine high priority candidates. The hazard

identification materials for the five chemicals will be presented at a future

meeting for Committee review for possible listing of the chemical under

Proposition 65. OEHHA anticipates announcing a similar request for relevant

information on the remaining four chemicals at a future date.

By this notice, OEHHA is providing the public an opportunity to provide

information relevant to the assessment of the evidence of carcinogenicity for

any of the chemicals listed in Table 1. Relevant information includes but

is not limited to: cancer bioassays, cancer epidemiological studies,

genotoxicity testing, and other pertinent data on pharmacokinetics, biomarkers,

and effects on biochemical and physiological processes in humans for any

of the five chemicals. Interested parties or members of the public wishing

to provide such information should send it to the address given below.

The publication of this notice marks the start of a 60-day data call-in

period. This period will end on Tuesday, December 15, 2009. The information

received during this data call-in period will be reviewed and considered

by OEHHA as it prepares the cancer hazard identification materials on these

chemicals. This request for information is the next step in the process

described in the 2004 prioritization procedure.

Notification of the availability of the hazard identification materials and

of the time, date, location, and agenda of the meetings of the Carcinogen

Identification Committee where these chemicals will be considered will be

provided in subsequent notices published in the California Regulatory Notice

Register and will also be posted on OEHHA’s website. It is anticipated

that the hazard identification materials will be made available for a 60-day

comment period prior to the Committee meetings at which these chemicals

will be considered.

Relevant information on these chemicals should be submitted to:

 

Cynthia Oshita

Office of Environmental Health Hazard Assessment

Proposition 65 Implementation

P.O. Box 4010

1001 I Street, 19th Floor

Sacramento, California 95812-4010

FAX: (916) 323-8803

Or via e-mail to _coshita_ (coshita)

Submittal of materials in electronic form is encouraged. It is requested

that all hard-copy materials be submitted in triplicate.

Submissions may also be delivered in person or by courier to the above

address. In order to be considered, the relevant information must be received

at OEHHA (if delivered in person or sent by FAX) by 5:00 p.m. on Tuesday,

December 15, 2009.

 

 

 

 

 

 

_http://www.oehha.ca.gov/prop65/CRNR_notices/state_listing/data_callin/sqe10

1509.html_

(http://www.oehha.ca.gov/prop65/CRNR_notices/state_listing/data_callin/sqe101509\

..html)

 

 

 

 

 

 

ck

 

 

 

New York State Coalition Opposed to Fluoridation, Inc.

_http://www.orgsites.com/ny/nyscof_ (http://www.orgsites.com/ny/nyscof)

 

Follow NYSCOF On Twitter:_ http://www.twitter.com/nyscof_

(http://www.twitter.com/nyscof)

 

Fluoridation News Releases

_http://tinyurl.com/NewsReleases_ (http://tinyurl.com/6kqtu)

 

Tooth Decay Crises in Fluoridated Areas

_http://www.fluoridenews.blogspot.com/_

(http://www.fluoridenews.blogspot.com/)

 

Fluoride Action Network

 

 

_http://www.FluorideAction.Net_ (http://www.fluoridealert.org/)

 

Fluoride Journal_ http://www.FluorideResearch.Org_

(http://www.fluorideresearch.org/)

 

Fluoride in the News:

_http://www.topix.net/drug/fluoride_ (http://www.topix.net/drug/fluoride)

 

 

 

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