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so you are saying that the combination of B6 with 5htp in the mainstream

products available don't work because of these scientific facts? and also

you are stating that one should take b6 and then after an hour should take

5htp because of the pharmokinetic nature of b6? i am not trying to commit to

this as a standard dosage requirements but if one was to infer a proper

understanding of interaction of b6 and 5htp this would be a good basis

correct?

 

 

__________

 

Raja Gursahani

(: 559.474.8576

,: rajagursahani

 

 

 

 

 

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Raja Gursahani-Ji Namaste:

 

I think you got the picture.

 

1. If Vitamin B-6 is present in the guts then it pre-maturely

converts 5-HTP into serotonin, which is eliminated by the kidneys.

You can easily check this using an HPLC equipped with an Electro

Chemical Detector (ECD).

 

2. One hour is not completely accurate, but can be regarded as an

approximate guideline.

 

3. I have not discussed dosage because individual requirements will

vary. For Example: $1 for a beggar (a starving individual) is not

same as $10 for a educate, gainfully employed, productive citizen of

the society.) 10 mg to 1200 mg of dosage has been reported in the

literature. In one of the studies 800 mg mg per day resulted in

patient loosing significant amount of weight and some companies are

using that paper to substantiate weight loss.

 

 

4. Chronic consumption of 5-HTP has been perceived that leads to

Vitamin B-6 Deficiency. I recall this was observed in a patient who

was suffering from Carpel Tunnel Syndrome and consuming large amounts

of 5-HTP.

 

About 12 years ago I had a whole cabinet full of papers on this

subject that I cleaned couple of years ago.

 

Best wishes,

 

Dr. Yadu

__________________________

so you are saying that the combination of B6 with 5htp in the

mainstream

products available don't work because of these scientific facts?

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Thank you Dr Yadu. so what is the quantity of b6 that needs to be ingested

approx 1 hour prior to ingesting 5htp? is it a one to one ratio?

 

 

__________

 

Raja Gursahani

(: 559.474.8576

,: rajagursahani

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Namaste Raja Gursahani-Ji:

 

Unfortunately, I never completed the pharmackkinetic studies as a the

funds for research depleted. More targeted research needs to be

completed before we will really find the answer peertaing to the

exact amount of B-6, 5-HTP and the time lag for optimum uptake.

 

Regards,

 

Dr. Yadu

 

_____________________

so what is the quantity of b6 that needs to be

ingested

approx 1 hour prior to ingesting 5htp? is it a one to one ratio?

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