Guest guest Posted March 22, 2008 Report Share Posted March 22, 2008 dear dr muzumdar with all due respect, how do you know they don't produce a toxic effect? subacute and/or chronic heavy metal toxicity may be difficult to detect - it would be very easy to confuse these symptoms for other diseases, years after administration. do you routinely conduct blood tests on patients to rule out toxicity? what external evidences including toxicological trials do you reference to support the use of bhasmas? todd caldecott __________________ > If prepared according to shastra, the bhasmas do not exhibit toxic > effects. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2008 Report Share Posted March 23, 2008 hey todd i would like to point out that there are chemistry professors in the department where i live who are being ruthlessly neglected with funding because of this heavy toxic metal propaganda being thrown by pharmaceutical companies that have huge amounts of cash to scare even the most authoritative western pedagogical scientists. this is including the american chemical association which i was a part of back in my teens as a research scientist assistant. let me translate this scientific language for you in other words, scientists wish to prove that these very metals that are present in bhasmas are not toxic as they are also readily found in the biochemical processes that occur not only in the brain but in the blood system of our own body. please do some research and you will see these chemical equations of metals in the body. they are standard knowledge. if you would like to speak to these neglected and violated scientists it may be useful to take a trip to local prestigious university and take a tour with a chemistry professor who deals with " inorganic chemistry " which is the chemisty of non carbon molecules. tell me please, is it politics you seek to play with or the truth??? whose side are you on my friend of ayurveda??? namaskar, __________ Raja Gursahani (: 559.474.8576 ,: rajagursahani Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2008 Report Share Posted March 24, 2008 Raja Gursahani Namaskar! > let me translate this scientific language for > you in other words, scientists wish to prove that these very metals > that > are present in bhasmas are not toxic as they are also readily found > in the > biochemical processes that occur not only in the brain but in the > blood > system of our own body. please do some research and you will see these > chemical equations of metals in the body. they are standard knowledge. If you seek to make your knowledge accessible how about simply providing the details? Otherwise it just sounds rather empty. I have done lots of research into minerals and there are NO known human physiological processes that _require_ heavy metals including lead, mercury, cadmium etc - certainly they may be present in the body in very tiny amounts, but that is because they also occur naturally or more frequently because of contamination. > > > tell me please, is it politics you seek to play with or the > truth??? whose side are you on my friend of ayurveda??? > The point i have made all along is that the evidence suggests that rasa shatra was incorporated into Ayurveda at a relatively late date in history, and that the current emphasis upon and use of bhasmas in modern-day Ayurveda does not reflect the practices of Charaka or his forebears. So I am not debating the merits or demerits of Ayurveda at all. However, if you can argue this point, and also provide sufficient toxicological data to prove that bhasmas containing heavy metals are safe for chronic administration, then I will be satisfied. Currently, there is more toxicological data on herbs such as Amalaki and Haridra, even though these are very safe with a long history of use as a medicine and food. So, why is there no data available on the heavy metal bhasmas, especially in light of what we know about their deleterious effects? Is there some kind of lobby that is preventing this? There are several herbs that I use that have toxic properties, or have been shown to be toxic. As a result, I have to admit their toxicity and modify my use. As a practitioner this is an important ethical consideration. Case in point is Comfrey (Symphytum officinalie), one of the best herbs I know to promote tissue healing. Most herbalists would never have thought this herb to be toxic 100 years ago, but recent evidence suggests that toxic pyrrolizidine alkaloids (PA) in Comfrey cause liver damage. Of course there is still some debate around this issue, but as a result, I am careful in my administration and always tell patients of the risk, something called " informed consent " . My other options are not to use it, or find PA-free versions of it. Please realize that your concerns as a general advocate of Ayurveda aren't the same as practitioner who is ethically and legally responsible for the products they recommend. I hope this clears up any further misunderstanding of my intent. The politics is already there, and in the West at least, to continue advocating or defending the use of toxic metals without any safety data is just BAD politics. best wishes.... todd caldecott Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 30, 2008 Report Share Posted March 30, 2008 dear Dr Muzumdar I appreciate that your argument is on based on GMPs (or maybe in this case we should say TMPs - or " Traditional Manufacturing Practices " ), but it nonetheless avoids the sticky issue that there are no toxicological trials on these medications, even those that have been prepared according to these GMP/TMPs. I mentioned the issue with Comfrey (Symphytum officinalis) in an earlier post. Most herbalists would have thought this herb 100% safe, and yet recent evidence suggests that the particular pyrrolizidine alkaloids in it cause damage in the liver on par with ionizing radiation, and that this effect may only be felt decades later. While it was very hard to hear, and I do have my thoughts about it, ultimately it is a piece of data I can't simply ignore and as a result have modified my use of this herb. I never asked that physicians conduct routine blood tests on all patients taking bhasmas, although by the standards of medical ethics this would be required. I am asking why are there no comprehensive toxicological trials on a population taking these products, given what we know about the inherent toxicity of heavy metals. If you are very confident that they are non-toxic I cannot see why you wouldn't support such trials, to demonstrate that concern is unwarranted. Caldecott todd www.toddcaldecott.com _______________________________ > I repeat that it is irresponsible prescribing and sub-standard > manufacturing that can cause episodes of toxic reactions. I get my > medicines prepared according to stringent Ayurvedic standards and > prescribe them strictly according to indications only, not just > because I want to make some opportunistic business. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 31, 2008 Report Share Posted March 31, 2008 The pharmacovigilance debate initiated by Todd should be welcomed by members. The increasing use of Ayurvedic products in the developed countries has led to increasing concern regarding their quality, efficacy and safety. The challenges relate to the patient, physician, regulatory authorities, the abuse/misuse of these medicines, quality and purity issues. Safety monitoring is mandated by a changing ecological environment, the use of insecticides, new manufacturing techniques, and the need to look at the active principles of these medicines as potential chemotherapeutic agents. In India we prefer the name “Bhasma” because they are burnt heavy metals carrying only the healing power. They are not heavy rather very light, healing micro powder that is able to work at cellular level. When metals are processed with fresh biological media (of herbal juices) and subjected to heat at extremely high temperatures. Thus Bhasmas are bound to change completely. The Bhasma becomes very potent, and should be taken only under the guidance of a knowledgeable physician. The conflict between the traditional ayurvedic practitioners and the purists demanding evidence of safety and efficacy needs to be addressed. Ayurvedic Bhasma Safety evaluation is the determination of safety for its human use to combat serious health problems. There is an urgent need for the practitioners of the allopathic and non-allopathic systems to work together to optimize the risk-benefit profile of these medicines. This is very essential to demonstrate the superiority of Ayurvedic Bhasma over modern chemical drugs. At the same time we have to characterize the potential toxic effects of Bhasma if any and have to determine the safe dosage levels in humans. There should be a joint commission of US FDA and overseas drug regulatory authorities to conduct clinical trials on ayurvedic Bhasma and not on heavy metals. Since we are concerning human safety, there should be not only comparative study with placebo but the trial should include comparisons of safety between Bhasmas & modern chemo-therapeutics also. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 31, 2008 Report Share Posted March 31, 2008 well said mukesh and to encourage solidarity among differing opinions I encourage your plan however integrity of this type of inquiry must be absolutely maintained. _____________________________ Raja Gursahani Cell 559.474.8576 Sent from my iPhone Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 3, 2008 Report Share Posted April 3, 2008 I do think it could be useful to check for blood toxicity for those using bhasma to form a strong case for them. But I think before that, it should be ensured that the bhasma are made in a way that will render them toxin free. Quote Link to comment Share on other sites More sharing options...
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