Prenatal toxicity linked to immune dysfunctions in later life.

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Prenatal toxicity linked to immune dysfunctions in later lifeMedical Research NewsPublished: Sunday, 6-May-2007http://www.news-medical.net/?id=24695A Cornell researcher and his wife have conducted the first comprehensivereview of later-life diseases that develop in people who were exposed toenvironmental toxins or drugs either in the womb or as infants.They have found that most of the diseases have two things in common: Theyinvolve an imbalanced immune system and exaggerated inflammatory reactions(at the cellular level).In an invited, peer-reviewed article on developmental immunotoxicity(DIT), published in a recent issue of Current Medicinal Chemistry, RodneyDietert, professor of immunotoxicology at Cornell's College of VeterinaryMedicine, and Janice Dietert of

Performance Plus Consulting in Lansing,N.Y., found that almost all the chronic diseases that are associated withDIT share the same type of immunological damage.The diseases linked to DIT include asthma, allergy, suppressed responsesto vaccines, increased susceptibility to infections, childhoodneurobehavioral conditions, autoimmunity, cancer, cerebral palsy,atherosclerosis, hypertension and male sterility.Toxins that are known to cause developmental immune problems in fetusesand neonates, according to the Dieterts, include herbicides, pesticides,alcohol, heavy metals, maternal smoking, antibiotics, diesel exhaust,drugs of abuse and PCBs.Antidotes to DIT, the researchers note, could come from a variety ofsources, including herbal and fungal chemicals -- from mushrooms to clover-- which appear to have promise.Two immune processes -- T helper (Th) cell balances and dendritic cellmaturation -- are both

compromised in ways that disrupt the regulation ofinflammatory cell function, which leads to exaggerated inflammatoryresponses."Most therapeutic approaches have looked at specific disease outcomes fromDIT, rather than focusing on the underlying immune dysfunction thatcreates the increased disease risk," said Rodney Dietert, who alsopresented his findings March 28 at the annual Society of Toxicologymeeting in Charlotte, N.C. "Instead, we looked at the common immunedysfunction that is related to a host of diseases."Knowing the most common immune dysfunction patterns from DIT allowsresearchers to consider more seriously those "medicinals with the capacityto restore inflammatory cell regulation, promote dendritic cell maturationand restore desirable Th balance that would be the most likely candidatesto combat the problems resulting from DIT."Focusing on studies of herbal and fungal chemicals, the Dieterts

scouredthe literature and found that some of the chemicals appear to beparticularly promising when taken at appropriate doses. These include:Astragalus; Echinacea (purple coneflower); sang-hwang shiitake, reishi,maitake and snake butter mushrooms, black seed, Asian ginseng, milk vetchroot, wild yam, Sophoro root and Greek clover (all of these also go byvarious other names).In their paper, the Dieterts also list a multitude of substances that havebeen found to have "an uncertain impact" on DIT as well as several foundto exacerbate immune dysfunction (including marijuana)."We hope that these findings of persistent immune dysfunction fromgestational exposure will provide encouragement for additional research.Furthermore, that researchers will look at these categories of medicinesthat have the possibility of correcting inflammatory and immune balanceproblems resulting from DIT rather than focusing solely on

individualdisease symptoms," Rodney Dietert said.He noted that until recently toxin-testing guidelines predicted only riskin adults, but that the Environmental Protection Agency has announced itwill issue new guidelines to take into account the increased immunesensitivity of fetuses and young children.http://www.cornell.edu>-----------------------US: 1 in 150 children has AutismUS: 1 in 6 children suffers a developmental disorderNew Jersey: 1 in 94 has Autism UK: 1 in 86 has Autism China : Over 20 lakh autistic children, India : No authentic figures, expected one crore+ (1 in 250) AUTISM IS NOTHING BUT MERCURY POISONING. THERE IS MERCURY IN VACCINES!!

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