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Get Plastic Out Of Your Diet

JoAnn Guest

Aug 31, 2006 09:16 PDT

 

 

Get Plastic Out Of Your Diet

PAUL GOETTLICH 16nov03

A similar version of this was published in

Living Nutrition magazine v.15, Spring (April) 2004

 

© Paul Goettlich

 

You Are What You Eat

 

 

When you eat or drink things that are stored in plastic, taste it,

smell it,wear it, sit on it, and so on, plastic is incorporated into

you. In fact,the plastic gets into the food and food gets into the

plastic and you.

So,quite literally, you are what you eat[1]. . . drink. . . and

breathe —plastic! These plastics are called " Food Contact

Substances " by the US Foodand Drug Administration (FDA), but until

April 2002, they were called

" Indirect Food Additives. " [2] The new name is cleansed of the

implication that plastic gets into your food. In spite of this

semantic deception, migration is a key assumption of the FDA.

 

According to Dr. George Pauli, Associate Director of Science Policy,

FDA Office of Food Additive Safety, the regulations mandated in 1958

assume that all plastics migrate toxins into the food they contact.

Migration is the movement of free toxins from plastic into the

substances they contact — in this case it's your food. The

manufacturer must " prove " that the migrations fall within an

acceptable range.[3] I agree with the assumption of migration

from all plastics, but I find a critical disparity between the level

ofscience employed by the regulations and the current scientific

knowledge regarding the levels at which they migrate and the effects

they can have. In particular, I am more concerned with extremely low

concentrations. There is also a conflict of interest in allowing the

manufacturer to submit its own testing to the FDA as proof of

anything. We invite the fox into the henhouse and are surprised when

there's nothing left but eggshells and feathers.

 

The amount of migration and corresponding toxicological effects are

highly disputed topics, even within the FDA, which has commonly

acquiesced toindustry in its regulation of technologies that are

used in the productionof our foods — plastics, pesticides, growth

hormones, irradiation, andmicrowave. This is clear from the mass of

expert and citizen testimony

against such technologies that regulatory agencies bend over

backwards

and

jump through flaming hoops to please their corporate clients, as

they

are

called.

 

There is a worst plastic for any purpose — polyvinylchloride (vinyl

or

PVC).

However, there is no best plastic to contain food or drink. It is my

hope

that this article will clarify this viewpoint. By the time you've

finished

reading, you should be closer to forming your own evaluation of

plastics.

 

Its Uses

 

Plastic is used in contact with nearly all packaged foods. Most

cardboard

milk containers are now coated with plastic[4] rather than wax. It is

sprayed on both commercial and organic produce to preserve its

freshness.

Plastic is even used to irrigate, mulch, wrap, and transport organic

food.

Organic bananas now come from wholesalers with a sticky plastic

wrapping

the

cut stem to protect the bananas from a black mold.[5] The mold is

controlled

on non-organic bananas by dipping the cut ends in a fungicide.

Chiquita

would only reveal that it's a " food grade plastic, " which means that

it

meets minimum regulatory standards. But since it has a sticky feel

to

it, I

suspect it either carries a fungicide or its physical

characteristics

act as

a fungicide. Either way, if it is or acts as a fungicide, the EPA

regulates

it as a pesticide, which fungicides are considered a subset of. [6]

In a

way, this is similar to the regulation of corn that is genetically

engineered to carry the toxic bacterium bacillus thuringiensis (Bt)

in

every

cell. Rather than the FDA regulating it as a food, the EPA regulates

it

as a

pesticide. Incredible as it may seem, they see our food as a

pesticide.

 

According to the FDA scientist I spoke with, it's a proprietary

formula

that

he doesn't know about and would offer nothing beyond that.

Disclosure of

proprietary information is a criminal offense.[7] All plastic

manufacturers

hide behind trade secrets. This is true with nearly all consumer

products.

It is quite impossible to know the chemical makeup of any plastic

without

paying a substantial amount of money for an independent lab analysis.

 

How is it made?

 

In a nutshell, plastic is made by combining monomers into polymers

under

great heat and pressure in a process called polymerization. Each

manufacturer has its own proprietary formula for each plastic. And

each

uses

a variety of additives such as plasticizers for flexibility, UV

filters

for

protection from sunlight, antistatic agents, flame-retardants,

colorants,

antioxidants, and more. Heavy metals such as cadmium, mercury, and

lead

are

common additives. There are also chemicals used to facilitate

production

such as mold releases, and countless other toxic chemicals regularly

added

to plastic consumer goods without our knowledge or approval. Many of

the

products and byproducts of the intermediary steps of plastics

production

are

used in other plastics or industrial processes and products such as

pesticides or fertilizer. For holistic thinkers, the mention of

plastics

and

pesticides in the same sentence should begin an informative thought

process,

while keeping in mind that they all have complete regulatory

approval.

 

The True Cost of Plastic

 

Plastic is ubiquitous in our lives because it is convenient and

relatively

inexpensive. It is advertised as safe and that it saves lives.[8]

Its

safety

is based on outdated science and regulations. And while it saves

lives

in

the short run, the record against plastic is looking quite different.

 

Its convenience comes from being lightweight and its ability to

absorb

impact shock without breaking, which on its own merit, is hard to

argue

with. It comes in an endless range of colors and finishes, is

pliable,

and

is easily formed and molded. Most would say it's a perfect material,

right?

Here's where the bad news begins.

 

Its inexpensiveness is the result of a large portion of the costs

associated

with its life — production, use and disposal — being put onto

society as

a

whole. This unsolicited financial burden on society manifests itself

as

increased taxes to finance municipal curbside recycling programs,

landfill

space, and incineration. It also increases health care and insurance

costs

as a result of its incineration polluting the air, water, and food.

I'll

give much more detail on the negative health effects later, but for

now,

suffice to say that a full and truthful lifecycle analysis would

reveal

that

the long-term negative health and socioeconomic effects at the local

and

global scales far outweigh the benefits realized by the use of

plastics.

 

What's so bad about plastic?

 

For decades, the plastics industry has deceived us with assurances

that

the

polymerization process binds the constituent chemicals together so

perfectly

that the resulting plastic is completely nontoxic and passes through

us

without a hitch. In spite of this industry disinformation,[9] the

polymerization process is never 100% perfect. Logically then, there

are

always toxicants available for migration into the many things they

contact —

your food, air, water, skin, and so on. Both the FDA and the

industry

know

this. However, because of many millions of dollars worth of

advertising

and

public relations work, consumers are educated to think that plastics

are

safe.

 

The additives utilized are not bound to the already imperfect

plastic,

leaving them quite free to migrate. One quick example: without a

plasticizer

additive, PVC would be rigid. The plasticizer resides between the

molecules

of the PVC, acting as a lubricant that allows those molecules to

slide

by

each other, and thus flex. Many containers used for food or water

are

made

of it. Even Barbie dolls are made of it. The plasticizer migrates

out

from

day one. And as it ages, the migration can visibly weep out of it.

[10]

 

Plastics, their additives and other processing chemicals can be

toxic at

extremely low concentrations. In fact, some are significantly more

toxic

at

extremely low concentrations than at much higher concentrations,

which

is

contrary to the FDA scientist's paradigm that, " The dose makes the

poison, "

meaning that the higher the concentration, the more toxic something

is.

It

is an interpretation of the writings of Paracelsus, an alchemist who

wrote

in the 16th century that, " Alle Ding sind Gift und nichts ohne Gift;

alein

die Dosis macht das ein Ding kein Gift ist " [All things are poison

and

nothing without poison; alone it is the dose that makes a thing no

poison].[11] It's now 500 years later and that assumption of

Paracelsus

is

still the basis for the many regulations. Except on chemical-by-

chemical

investigations by various independent, institutional, and academic

labs,

plastics are not explored for harmful effects or regulated in any

meaningful

way.

 

Extremely Low Doses and Synergy

 

Since it is known that all plastics migrate into food, it behooves

us to

look for the evidence at meaningful levels of detection, at and below

single-digit parts-per-trillion (ppt) or ng/kg. Extremely low doses

are

especially relevant because they can upset the natural balance of the

endocrine system. To paraphrase the report of an EPA workshop in

1996,

endocrine disruptors (EDs) are external agents that interfere with

the

production, release, transport, metabolism, binding, action or

elimination

of natural hormones in the body responsible for maintaining internal

balances and the regulation of developmental processes.[12]

 

Current knowledge of EDs turns the work of Paracelsus — that guy

born in

the

15th century — upside down. Some chemicals can be more toxic at

extremely

low doses than extremely high doses. The timing of the exposure can

be

much

more relevant than its dose. Most vulnerable times are in periods of

rapid

growth, such as those in embryo and children right up to puberty.

They

can

be exposed in the womb and before conception, if sperm and/or ovum

are

contaminated. The maladies of the children of Gulf War veterans are

a

prime

example of this type of exposure.[13]

 

Synergy is an important issue that is mostly disregarded by the FDA.

Many

will even debunk the idea that low dose synergy is real. In

combination

with

other commonly used products, the toxicity of the migratory

chemicals

from

plastics can be potentiated by synergy. A synergy can occur between

two

or

more chemicals that elevate the combination's toxicity to hundreds

of

times

greater than that of the individual chemicals. Besides plastics,

other

household chemicals can be part of a synergy with plastics.

 

Nuclear radiation can also severely damage the endocrine system.

According

to Dr. Ernest Sternglass, Professor Emeritus of Radiological Physics

at

the

University of Pittsburgh Medical School, the synergy between nuclear

radiation and chemical toxicants is well documented.[14] Gulf War

vets

(I

and II) were and still are being exposed to depleted uranium (DU)

from

the

tons of armour-busting shells they fired being distributed across

the

Gulf

Region as an aerosol smaller than the size of a virus.[15] The

hazardous

materials (MOPP) suit that soldiers are given do not protect them

from

the

infinitesimally small particles of DU because the high efficiency

particulate air (HEPA) filters do not work below 1/10 of a micron

(0.1µ).

Each one of us is exposed to extremely low levels of radiation from

the

nuclear power plants scattered about the US.[16]

 

On the home front, even the products in our day-in and day-out

humdrum

lives

are coated with, contain, or are made of synthetic chemicals that can

interact synergistically with each other. The list is endless but

includes

beauty products such as nail polish, eyeliner, deodorant and

aftershave;

household cleaning products such as tile and carpet cleaners, air

fresheners

that are solid, plug-in, or spray. Even gas and diesel engine

exhaust

are

included. Quite frankly, the FDA doesn't even consider all sources

of a

chemical in its review of industry product applications.

 

Consider that there between 87,000 to 100,000 chemicals in commercial

production. At the time I wrote this, there were 22,241,247 organic

and

inorganic substances registered with Chemical Abstracts Service (CAS)

registry.[17] Only eight months before that, there were 1,112,474

fewer

chemicals.[18] They are regulated and tested in what I would call a

" don't

look — don't see " style of science that boggles the minds of those

who

look

just a little below the surface of the happy little corporate-

science

myths.

The focus is on the wonders of plastic with a purposeful avoidance

of

the

painfully evident negative human and environmental health effects.

Using

the

more conservative 87,000 chemicals, there are approximately

1.063725377

x

1086,991 different combinations possible that could have a

synergistic

effect on toxicity.[19] For the purposes of this article, that

number is

roughly 1 with 87,000 zeros after it. Even if researchers had the

time

and

money to test them all, they still wouldn't know what to look for,

because

there is no precedent. In addition, one must account for the

uniqueness

of

each living organism and its unique environment, which further

expand

the

possible synergies and possibilities.

 

Water Stored in Plastic

 

Water bottles are be made from various types of plastic —

polycarbonate

(PC), polyethylene terephthalate (PET), Polypropylene (PP), high-

density

polyethylene (HDPE), low-density polyethylene (LDPE), polyvinyl

chloride

(PVC or vinyl), and others. To reiterate, they all migrate to some

degree. I

will focus on just one chemical that migrates out of one plastic

that is

used to make products with high use and sales profiles.

 

Bisphenol-A (BPA) is a monomer used in the synthesis of PC plastics,

epoxy

resins, and composites, as well as a heat stabilizer in PVC. The

list of

products containing BPA is long. Some rigid containers such as water

and

baby bottles are made of PC. The popular Nalgene® water bottles are

made

of

Lexan® brand PC. In the medical industry, it is used for syringes,

containers, lenses, and dental products. Keep in mind that the FDA

regulates

only plastics in contact with foods and not any of the other

exposures a

person might commonly experience every day at home, school, or the

office.

Because the FDA approves plastics for specific uses rather than for

individual chemicals, BPA is not explicitly regulated.[20] It is

important

to note that all exposures, no matter what origin, are relevant and

cumulative. Even other chemicals that act in the body in similar

ways

can be

part of the total effect. The body's natural defenses try to

breakdown

toxins as they enter. These are called metabolites and can be

significantly

more toxic than the original chemical.

 

Today it is common that dentists coat children's teeth with dental

sealants

[21] that harden (polymerize) within the mouth. This exposure to BPA

is

large enough to have biologic effects. [22] Just as with other

plastics,

dental sealants polymerize imperfectly, leaving free monomers to be

ingested

or absorbed through the skin within the mouth. When it comes to

dental

solutions without plastic, the choices are limited. And I must say

that

I am

extremely frustrated by the situation. One orthodontist I spoke with

creates

retainers from metal wire that can replace the standard

polycarbonate

ones.

In tooth replacement, even some materials that dentists call ceramic

have a

polymer matrix. Gold caps or crowns are an excellent choice, but

they

too

are glued into place with a volatile polymer. By far, the best

alternative

is to keep your teeth healthy by brushing and flossing regularly,

and by

eating a healthy diet.

 

Food and beverages cans are coated with a BPA-containing plastic.

During

the

processing of canned food, it is sterilized in the can at 250°F for

1

hour.

Because heat increases its migration, this is an especially large

exposure

for people who eat canned foods. As PC plastics grow old, BPA and

other

chemicals are released. But even when they are new BPA migrates out

of

PC

plastic.

 

The Code of Federal Regulations section on PC plastics allows for

migratory

chemicals in the hundreds of parts-per-million (ppm) range as well

as a

percentage of the plastic's total weight. While concentrations of

ppm

and

higher are relevant, there is vast area of exposure that falls well

below

the FDA's radar in the parts-per-trillion (ppt) range and lower.

Testing

methods are available, but the cost would be far greater. Because the

industry is responsible for testing, it protests madly about the

idea

that

these concentrations are relevant. If the table was turned and the

burden of

proof was on the consumer, the FDA would demand the most up to date

testing

methods. A graphic example of 1 ppt is one drop of liquid in 660

rail

tank

cars. That's a train 6 miles long!

 

In the year 2000, Consumers Union (CU) tested water from five-gallon

PC

plastic bottles for BPA, They found from 0.5 ppb to 11 ppb in water

samples

from eight of the ten 5-gallon jugs.[23] After industry spin-meisters

discredited the study as being flawed, not many regulatory red

flares

were

sent up within the FDA. This type of industry disinformation is

standard

operating procedure. Most times, the statements made could be

compared

it to

one child calling another derogatory names, hoping that the

recipient

will

become persona non grata with the other children. However, the CU

study

was

indeed valid and the concentrations of BPA that were found are

extremely

relevant.

 

CU also found BPA in samples from baby bottles at worrisome levels.

[24]

CU

advised its readers to avoid exposure to BPA by " dispos[ing] of

polycarbonate baby bottles and replac[ing] them with bottles made of

glass

or polyethylene, an opaque, less-shiny plastic that does not leach

bisphenol-A. " [25] That advice attracted the wrath of the plastics

industry.

But I will go further and advise readers not to serve or store any

food

liquid or solid, water-based or fatty, hot or cold — in any plastic.

 

In April 2003, a study was published about BPA accidentally killing

mice

that had been held in polycarbonate cages at a lab.[26] It was found

accidentally when it ruined a lab experiment that heated yeast in PC

flasks

to find out if the yeast produced estrogens. It was discovered that

BPA

from

the PC flasks was the material that was estrogenic, and that it

competed

with the natural estrogen in a rat's body. [27] I asked one noted

researcher

why labs still use plastics considering what it has been known since

1993

that BPA migrates and is hormonally active. The response was, " What

are

we

supposed to do, go back to glass? " The tone of voice made it seem as

if

I

had advised going back in time to live in the Stone Age. This is the

state

of what is still amazingly called science. There is a lack of reason

and

logic that goes well beyond what I knew possible before I began

looking

at

the many aspects of this technology. Truth is sought, but the

obvious is

knocked to the ground and trampled over in the stampede to secure

funding.

 

BPA's Rap Sheet

 

The list of negative health effects associated in some way with

exposure

to

BPA is remarkably long. The most visible effect may be aneuploidy, a

chromosome abnormality found in more than 5% of pregnancies. Most

aneuploid

fetuses die in utero. About one-third of all miscarriages are

aneuploid,

making it the leading known cause of pregnancy loss. Among

conceptions

that

survive to term, aneuploidy is the leading genetic cause of

developmental

disabilities and mental retardation. About 1 in 300 liveborn infants

and

1

in 3 miscarriages are aneuploid. It is associated with Down

syndrome,[28]

Patau syndrome, [29] Edwards syndrome,[30] Klinefelter syndrome,

[31]

Turner

syndrome, [32] Cri du chat syndrome, [33] and Alzheimer's disease.

[34]

And

each of these bears its own extensive list of maladies covering all

parts

and functions of the human body — both physical and mental. The

condition

at birth is directly related to the type of chromosome abnormality

present

in the embryo at the time of conception.[35] It is well documented

that

aneuploidy contributes to the increased risk of spontaneous abortion

when

the female partner is older, but it is also thought that males more

than

30

years old may increase the risk of spontaneous abortion when the

female

partner is less than 30 years of age.[36]

 

Being one of many known endocrine disruptors, BPA affects

development,

intelligence, memory, learning, and behavior, skeleton, body size

and

shape,

significant increase in prostate size, decreased epididymal weight

and a

longer anogenital distance,[37] prostate cancer, [38] reduced sperm

count,[39] both physical and mental aspects of sexuality. It may have

something to do with obesity,[40] and so many more that a separate

article

is required to list them all. In other words, if the fetus lives,

any

one or

many parts of its body can be permanently affected. The problems may

become

evident at any age.

 

Alzheimer's disease generally occurs after the age of 50. In those

afflicted

with it, areas of brain become smaller with cell death and the

cavities

left

become enlarged. The areas most affected are control memory, logical

thinking, and personality. Only 5-10% of the cases are inherited. 14

million

people with Alzheimer's disease are predicted by 2050.

 

BPA is about 10,000-fold less potent than 17ß-estradiol, a potent

estrogen

that is synthesized primarily in the ovary, but also in the

placenta,

testis

and possibly adrenal cortex. Because of the disparity, industry

representatives claim it causes no harm at the levels that the

majority

of

people are exposed to. However, a study in 2001 showed that even at

such

low

potency, when combined with other xenoestrogens (estrogens from

outside

the

body), they act together additively, effectively raising the body

load

of

estrogen to dangerous levels.[41] Another study showed that there is

an

increased sensitivity to BPA during the perinatal period, which

begins

with

completion of the twentieth to twenty-eighth week of gestation and

ends

7 to

28 days after birth.[42] Exposure to BPA increases risk of mammary

tumors.[43] To reiterate, there is no shortage of research published

on

the

negative health effects of BPA.

 

Avoiding Plastic

 

While it's impossible to avoid all plastics, we must rid our diets

and

lives

of this toxic material as much as possible. There is a huge amount

of

data

confirming the migration of plastic monomers and additives in all

steps

of

food processing.[44] And in my opinion and that of many top research

scientists, it is only a matter of time and money spent on new

studies

before the harm is found. Because of corporate political campaign

financing,

meaningful regulations resulting from studies will take even longer

to

become law. We must protect our families while the obvious results

trickle

in.

 

I strongly advise individuals and governments to ban plastics

wherever

possible by utilizing the precautionary principal. The Wingspread

Statement

on the Precautionary Principle is the consensus statement of a

conference in

1998. Simply put it states that if you have reasonable suspicion of

harm

coming from (plastic in this case) then you must stop it from

happening;

the

burden of proof must be on industry, not consumers; alternatives

must be

fully explored before using a new material or technology; and any

decisions

regarding such activities must be " open, informed, and democratic "

and

" must

include affected parties. " [45]

 

Evidence of the negative health effects of plastics already exists in

sufficient quantity to halt the use of it in contact with food. More

importantly, I feel that the manufacture of plastic itself must be

halted

for a multitude of reasons. Besides causing an endless number of

human

deaths, disabilities, and diseases, plastic is clogging all habitats

of

the

world and destroying the ecosystem. There is now 6 times more

plastic

than

plankton floating around in the middle of the Pacific Ocean.

Plankton is

a

major food source for sea animals.[46] A large portion of it is

preconsumer

plastic that has not been made into a product yet. Called nurdels,

they

look

very much like plankton in size and color. According to a paper by

Arrigo et

al in Geophysical Research Letters in October 2003, plankton

production

has

been declining for the last 20 years with rising ocean surface

temperatures.

Along with increasing plastic quantities, the ratio of plastic to

plankton

is increasing, making it more of a target for hungry animals.

 

The researcher who found this, Captain Charles Moore, Director of the

Algalita Marine Research Foundation, told me that new data indicate

that

the

ratio of plastic to zooplankton is even higher in two so-called

floating

plastic " Garbage Patches " that are each bigger than the State of

Texas.[47],

[48]

 

Nurdles are incorporated into all strata of the oceans with no known

method

of removal. DDE, a metabolite of DDT, and other dioxin-like chemicals

concentrate on the surface of the plastic nurdles at a rate up to a

million

times that found in the ocean.[49] Captain Moore's presentation

includes

images of sea animals that have suffocated and starved as a result.

Even

more startling is seeing plastic bits incorporated into the flesh of

the

sea

animals.

 

Conclusion

 

I spent about two years answering telephone inquiries at an

environmental

organization in Berkeley. A great number of the callers asked what

the

safest plastic to use in contact with food or water is. They also

wanted

to

know what the safest plastic is to microwave food in. My answer was

that

plastic should never contact food. And that one should never

microwave

food

— it's probably as bad or worse than putting it in plastic because it

creates free radicals in the food that damage cells in your body. It

also

heats the plastic, thus increasing the rate of migration into the

food.

That

answer wasn't popular with either the caller or the organization,

which

likes to point out positive alternatives. However, plastic is the

alternative! And glass, wood, metal, and ceramics are the real

things.

Plastic is merely a foul imitation thereof. By using the least

offensive

plastic, one only prolongs and increases the toxic load on the Earth

and

in

our bodies. If saving trees is your aim, stop using so much stuff.

But

in

the mean time, don't further degrade the environment with more

plastic.

 

As consumers, we always look for ways to maintain the status quo of

our

modern lives. However, the only logic I can see in the regulation of

food

contact plastics is profit at the expense of our health, the economy,

society, and environment. You needn't be a polymer scientist to know

that

plastic shouldn't contact food. What is essential though is a firm

standing

in reality and a good grip on logic. It also requires being free of

ties

to

the industry before that logic becomes evident.

 

First set aside your assumptions and look at the known long- and

short-term

negative effects of plastic on health, economy, environment, and

society, as

well as the long-term viability of the human race. Next contrast

that

with

what you find as benefits. I guarantee that the stack of chips will

be

far

larger in the negative pile.

 

If one were to listen only to nonprofits and the industry, it would

be

natural to think that only the additives are toxic and migrate. But

everything about plastics is toxic — both the additives and the base

plastics. And both migrate in quantities that are problematic at

extremely

low concentrations. Some chemicals are obviously more so than

others.

But it

is undeniable that they all migrate all the time into everything

that

they

touch.

 

Consider that:

 

Ubiquitous — plastics are everywhere. . . our bodies, the air,

water,

oceans

and so on

 

Toxic — plastics are toxic. Both additives and base plastics

 

World — almost everything we touch is made of or coated with plastics

 

People — we are all exposed during every every minute of every day

 

Unknown — almost nothing is known about individual chemicals that

make

up

plastics

 

Synergies — even less than nothing is known about the effects of

combinations of plastics and other things including ionizing

radiation

 

Wishful thinking — the process by which plastics are considered safe

by

the

FDA, the industry, nonprofits and users

 

Further Reading

 

Alternatives to Plastic Paul Goettlich 3aug2005

 

Be sure to browse through the Plastics index of Mindfully.org

 

78 Reasonable Questions to Ask about Any Technology - Stephanie

Mills /

Clamor, i.18, Jan/Feb03

 

Identification Of Volatile Organic Compounds In a New Automobile -

Scientific Instrument Services 23dec99

 

EDSTAC Review - Davis Baltz / Commonweal 6may00

 

Middlesex and the Limitations of Myth - Thea Hillman / ISNA News

Spring03

 

 

References

 

[1] Brillat-Savarin, JA. Physiologie du Gout, ou Meditations de

Gastronomie

Transcendante...Paris: Sautelet et Cie, 1826. Note: Jean Anthelme

Brillat-Savarin (1755-1826) was a French lawyer and politician who

achieved

fame through a book, Physiologie du Gout. " You are what you eat

comes

from

the quote by Brillat-Savarin " Tell me what you eat and I will tell

you

what

you are. "

[2] Guidance for Industry: Preparation of Food Contact Notifications

and

Food Additive Petitions for Food Contact Substances: Chemistry

Recommendations FINAL GUIDANCE U.S. Food and Drug Administration,

Center

for

Food Safety & Applied Nutrition, Office of Food Additive Safety

April

2002

http://www.cfsan.fda.gov/~dms/opa2pmnc.html

[3] Telephone conversation with Dr. George Pauli, Associate Director

of

Science Policy, FDA Office of Food Additive Safety, and Mike

Herndon,

Head

of Media, FDA Office of Food Additive Safety 22 October 2003 12:49 PM

[4] Polyethylene (source FDA telephone conversation)

[5] Cladosporium: Ascomycete. The most common mold in the world,

found

in

soil and on textiles, tomatoes, spinach, bananas, and dead

vegetation.

For

image http://www.carolinafilters.com/FunclspP.jpg

[6] Fungicides are a category of pesticide as regulated by the EPA.

See

What

is a Pesticide? U.S. EPA Office of Pesticide Programs 14feb97

http://www.mindfully.org/Pesticide/What-Is-A-Pesticide.htm

[7] Telephone conversation with Dr. George Pauli, Associate Director

of

Science Policy, FDA Office of Food Additive Safety, and Mike

Herndon,

Head

of Media, FDA Office of Food Additive Safety 22 October 2003 12:49 PM

[8] Plastics: An Important Part Of Your Healthy Diet You could think

of

them

as . . . Advertising by the American Plastics Council found in

National

Geographic magazine (abt.1996)

http://www.mindfully.org/Plastic/6th-Basic-Food-Group.htm

[9] Disinformation pronunciation: ( " )di- " sin-f & r-'mA-sh & n Function:

noun

1939 : false information deliberately and often covertly

spread

(as by

the planting of rumors) in order to influence public opinion or

obscure

the

truth Merriam-Webster online http://webster.com/

[10] Barbie's PVC Body Gets Sticky as Dibutyl Phthalate Migrates

Yvonne

Shashoua / Conservation Department The National Museum of Denmark

19apr99

http://www.mindfully.org/Plastic/Barbies-Health-Hazard.htm

[11] Paracelsus: Dose Response. in the Handbook of Pesticide

Toxicology

WILLIAM C KRIEGER / Academic Press Oct01. Robert Krieger, ed.

University

of

California, Riverside, Riverside, California, U.S.A.

http://www.mindfully.org/Pesticide/Paracelsus-Dose-

ToxicologyOct01.htm

[12] Research Needs for the Risk Assessment of Health and

Environmental

Effects of Endocrine Disruptors: A Report of the U.S. EPA-sponsored

Workshop

Environmental Health Perspectives, v.104, s.4, Aug96

http://www.mindfully.org/Pesticide/RJ-Kavlock-et-al-Aug96.htm

[13] What Are Endocrine Disruptors? Paul Goettlich 2jul03

http://www.mindfully.org/Pesticide/EDs-PWG-16jun01.htm

[14] Telephone conversation with Ernest Sternglass, Ph.D., Professor

Emeritus of Radiological Physics at the University of Pittsburgh

Medical

School has written numerous articles on the health effects of low-

level

radiation. He is Director and Chief Technical Officer of the RPHP

Baby

Teeth Study [www.rphp.org].

[15] Leuren Moret Speaking on Depleted Uranium in Los Altos,

California

21apr03 http://www.mindfully.org/Nucs/2003/DU-Leuren-Moret21apr03.htm

[16] As evidenced by strontium-90 being detected by the Tooth Fairy

Project

in many thousands of baby teeth

http://www.radiation.org/envelope.html

[17] CAS Registry Numbers for new compounds and assistance with

nomenclature

can be obtained by writing to Chemical Abstracts Service (CAS) Client

Services, 2540 Olentangy River Road, P.O. Box 3343, Columbus, OH

43210,

or

by visiting their website at http://www.cas.org

[18] Today's date: 9 October 2003

[19] Formula: 2^n - n - 1 This is called a factorial. Dr. Bruce

Sagan, a

mathematician at Michigan State University, did the calculation.

Example:

where 2^n means 2 to the power n. So, for example, when n = 10 then

there

are 2^10 - 10 - 1 = 1024 - 11 = 1013. This formula accounts for

duplications

such as 1,2,3 = 1,3,2 = 2,3,1 = 2,1,3 = 3,1,2 = 3,2,1

[20] 21 CFR § 177.1580 Polycarbonate Resins. Code of Federal

Regulations

rev.1apr03

http://www.mindfully.org/Plastic/PC/21CFR177.1580-Polycarbonate-

1apr03.htm

 

[21] Bisphenol-A (BPA) For Doctors and Dentists. Paul Goettlich

7may02

http://www.mindfully.org/Plastic/Plasticizers/Bisphenol-A-For-

Doctors-Dentis

 

ts.htm

[22] Determination of Bisphenol A and Related Aromatic Compounds

Released

from Bis-GMA-Based Composites and Sealants by High Performance Liquid

Chromatography Environmental Health Perspectives v.108, n.1, Jan00

http://www.mindfully.org/Plastic/Bisphenol-A-Aromatic-Compounds.htm

[23] http://www.mindfully.org/Plastic/5-Gallon-Water-Jugs.htm

[24] Food For Thought: What's Coming Out of Baby¹s Bottle? Janet

Raloff

/

Science News 31jul99 v.156, n.5

http://www.mindfully.org/Pesticide/Babys-Bottle-Roloff.htm also see:

http://www.mindfully.org/Plastic/Plasticizers/BPA-Baby-

BottlesJul03.htm

[25] Baby Alert: New Findings about Plastics Consumer Reports

Special

Report

21apr99 http://www.mindfully.org/Plastic/Baby-Bottles-CU21apr99.htm

[26] BPA and Plastic Lab Animal Cages When Disaster Strikes:

Rethinking

Caging Materials Lab Animal v.32, n.4, Apr03

http://www.mindfully.org/Plastic/Plasticizers/BPA-Lab-Animal-

CagesApr03.htm

 

Also see: Bisphenol A Exposure Causes Meiotic Aneuploidy in the

Female

Mouse

Current Biology, v.13, 1apr03

http://www.mindfully.org/Plastic/Plasticizers/BPA-Mouse1apr03.htm

[27] Bisphenol-A: an estrogenic substance is released from

polycarbonate

flasks during autoclaving Endocrinology 132(6):2277-8 Jun93

http://www.mindfully.org/Plastic/BPA-Polycarbonate-Flasks.htm

[28] Terry Hassold and Patricia Hunt. To Err (meiotically) Is Human:

The

Genesis of Human Aneuploidy Nature Reviews Genetics 2, 280 -291

(2001);

V.2,

n.4 Apr01

http://www.nature.com/cgi-taf/DynaPage.taf?

file=/nrg/journal/v2/n4/abs/nrg04

 

01_280a_fs.html

Also see: Bisphenol A Exposure Causes Meiotic Aneuploidy in the

Female

Mouse

Current Biology, v.13, 1apr03

http://www.mindfully.org/Plastic/Plasticizers/BPA-Mouse1apr03.htm

[29] Patau Syndrome - Robert G Best, PhD, Director, Professor,

Department of

Obstetrics and Gynecology, Division of Genetics, University of South

Carolina School of Medicine - eMedicine.com

http://author.emedicine.com/ped/topic1745.htm

[30] Edwards syndrome - Harold Chen, MD, MS, FAAP, FACMG, Chief,

Professor,

Department of Pediatrics, Section of Perinatal Genetics, Louisiana

State

University Medical Center - eMedicine.com

http://www.emedicine.com/ped/topic652.htm

[31] Klinefelter syndrome - Harold Chen, MD, MS, FAAP, FACMG, Chief,

Professor, Department of Pediatrics, Section of Perinatal Genetics,

Louisiana State University Medical Center

http://www.emedicine.com/ped/topic1252.htm

[32] Campbell Biology 6th ed.

http://webpages.marshall.edu/~adkinsda/B111OutlinesChromInhAlt.html

Verified

by personal conversation with author of the URL, Dr. Dean A. Adkins,

a

biology professor at Marshall University

[33] Cri-du-chat syndrome - Harold Chen, MD, MS, FAAP, FACMG, Chief,

Professor, Department of Pediatrics, Section of Perinatal Genetics,

Louisiana State University Medical Center. eMedicine.com

http://www.emedicine.com/ped/topic504.htm

[34] Alzheimer Disease - Jeffrey A Gunter, MD, Staff Physician,

Department

of Surgery, Division of Emergency Medicine, Denver Health Medical

Center.

eMedince.com http://www.emedicine.com/aaem/topic12.htm

[35] Reproductive Science Center of the San Francisco Bay Area

website

14oct03 http://www.rscbayarea.com/articles/pgd_indications.html

[36] Does Male Age Affect the Risk of Spontaneous Abortion? An

Approach

Using Semiparametric Regression - Am. J. Epidemiol. 2003 157: 815-

824.

1may03 v.157, i.9

http://ifr69.vjf.inserm.fr/~web292/fer/Remyhtml/Slama5-2003-

AmJEpidemiol.pdf

 

[37] Reproductive Malformation of the Male Offspring Following

Maternal

Exposure to Estrogenic Chemicals - Proceedings of the Society for

Experimental Biology and Medicine 224:61-68 Jun00

http://www.mindfully.org/Pesticide/Maternal-Exposure-Repro-

Malform.htm

[38] The Xenoestrogen Bisphenol A Induces Inappropriate Androgen

Receptor

Activation and Mitogenesis in Prostatic Adenocarcinoma Cells -

Molecular

Cancer Therapeutics May 2002

http://mct.aacrjournals.org/cgi/content/abstract/1/7/515

[39] Sakaue, M, S Ohsako, R Ishimura, S Kurosawa, M Kurohmaru, Y

Hayashi, Y

Aoki, J Yonemoto and C Tohyama. 2001. Bisphenol-A Affects

Spermatogenesis in

the Adult Rat Even at a Low Dose. Journal of Occupational Health

43:185

-190.

[40] A Synthetic Antagonist for the Peroxisome Proliferator-activated

Receptor Inhibits Adipocyte Differentiation - J Biol Chem, Vol. 275,

Issue

3, 1873-1877, January 21, 2000.

http://www.jbc.org/cgi/content/full/275/3/1873

[41] Rajapakse, N, D Ong and A Kortenkamp. 2001. Defining the Impact

of

Weakly Estrogenic Chemicals on the Action of Steroidal Estrogens.

Toxicological Sciences 60: 296-304.

http://www.mindfully.org/Pesticide/Estrogenic-Steroidal-

EstrogensApr01.htm

 

[42] PPT presentation by James Tilton, PhD, Professor of Reproductive

Physiology, Department of Animal & Range Sciences, North Dakota State

University, Fargo, ND

http://www.ndsu.nodak.edu/ndsu/jtilton/powerpointpresentations/gonado

tropins

 

..ppt

[43] Beverly S. Rubin et al. Perinatal Exposure to Low Doses of

Bisphenol A

Affects Body Weight, Patterns of Estrous Cyclicity, and Plasma LH

Levels.

Environmental Health Perspectives Volume 109, Number 7, July 2001

http://ehpnet1.niehs.nih.gov/members/2001/109p675-680rubin/rubin-

full.html

 

[44] Email communication (9oct03) with Dr. Nicolas Olea, Dept.

Radiologia y

Medicina Fisica, Facultad de Medicina, Universidad de Granada,

Granada

18071, Spain http://www.ugr.es/university.htm

[45] The Wingspread Statement on the Precautionary Principle Rachel's

Environment & Health News n.586, 19feb98

http://www.mindfully.org/Precaution/Precautionary-Principle-

Rachels.htm

[46] A comparison of plastic and plankton in the North Pacific

central

gyre

- Marine Pollution Bulletin, v.42, n.12, Dec01

http://www.mindfully.org/Plastic/Moore-North-Pacific-Central-Gyre.htm

[47] Email from Charles Moore, Director of the Algalita Marine

research

Foundation.

[48] I am an advisor to the Algalita Marine Research Foundation

(AMRF)

in

Long Beach, CA www.algalita.org

[49] Plastic Resin Pellets as a Transport Medium for Toxic Chemicals

in

the

Marine Environment - Environ. Sci. Technol. 2001, 35, 318-324

http://www.mindfully.org/Plastic/Pellets-Transport-Medium.htm

 

 

JoAnn Guest

mrsjo-

www.geocities.com/mrsjoguest/Diets

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