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HEALTH: Green Tea - Glycine May Slow Tumor Growth

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Green Tea - Glycine May Slow Tumor Growth

 

Nov. 2, 2001 --

 

You've probably read that green tea appears to protect against cancer.

You may even know that its anti-cancer properties are attributed to an

abundance of chemicals called polyphenols. But new research may explain,

for the first time, how those chemicals fight tumors at a molecular

level.

 

Using prostate cancer cell lines, researchers from H. Lee Moffitt Cancer

Center in Tampa, Fla., found that polyphenols in green tea, and black

and red teas for that matter, target a protein known to protect cancer

cells from death.

 

The research, along with several other studies evaluating the anti-tumor

properties of food components, was presented this week at an

international conference in Miami Beach, Fla.

 

The amino acid glycine was found to reduce breast tumor growth in rats.

Apparently, it blocks the growth of new blood vessels that feed tumors.

Glycine is manufactured in the body, but is also commercially available

as a dietary supplement.

 

" These are very preliminary studies, but they are quite interesting, "

American Association for Cancer Research (AACR) President Waun Ki Hong,

MD, tells WebMD. He says that human studies are needed to verify the

findings, but this may represent an important contribution to the

research. AACR co-sponsored the annual meeting along with the National

Cancer Institute and the European Organization for Research and

Treatment of Cancer.

 

In the green tea research, Aslamuzzaman Kazi, PhD, and colleagues found

that polyphenols reduced the level of Bcl-XL protein in prostate cancer

cell lines. Bcl-XL has been shown to protect cancer cells from death --

known scientifically as apoptosis. " The higher the concentration [of

polyphenols] the more apoptosis, " Kazi tells WebMD. " Epidemiological

studies have shown that tea has anticancer activities. We wanted to try

to understand the molecular mechanism of this action. "

 

Studies in humans have, in fact, been inconclusive regarding the role of

tea in preventing or slowing cancers. While some have shown a clear

protective benefit, others have not. The most recent large study,

published last March in The New England Journal of Medicine, found that

drinking green tea did not lower the risk of developing stomach cancer

in a group of Japanese subjects.

 

In the glycine study, researcher Zishan Haroon, MD, PhD, and colleagues

at Duke University Medical Center, found high levels of glycine reduced

breast tumor growth rates by 15% in rats by blocking the growth of new

tumor-feeding blood vessels. The special diet also reduced wound-healing

by 30%, which, Haroon tells WebMD, explains glycine's effect on tumors.

" Tumors and wounds have one very important thing in common -- they both

produce new blood vessels through the same mechanism, known as

angiogenesis, " he says. If you can block one response, you can block the

other, he says.

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Unfortunately green tea also has a high fluoride content.

Enough to make me avoid it anyway.

ron

_____________

Get the FREE email that has everyone talking at

http://www.mail2world.com

 

<>

>

> Femme

> 11/9/2001 7:09:15 AM

> To:

> HEALTH: Green Tea - Glycine May Slow Tumor

Growth

>

> Green Tea - Glycine May Slow Tumor Growth

>

> Nov. 2, 2001 --

>

> You've probably read that green tea appears to protect against cancer.

> You may even know that its anti-cancer properties are attributed to an

> abundance of chemicals called polyphenols. But new research may

explain,

> for the first time, how those chemicals fight tumors at a molecular

> level.

>

> Using prostate cancer cell lines, researchers from H. Lee Moffitt

Cancer

> Center in Tampa, Fla., found that polyphenols in green tea, and black

> and red teas for that matter, target a protein known to protect cancer

> cells from death.

>

> The research, along with several other studies evaluating the

anti-tumor

> properties of food components, was presented this week at an

> international conference in Miami Beach, Fla.

>

> The amino acid glycine was found to reduce breast tumor growth in

rats.

> Apparently, it blocks the growth of new blood vessels that feed

tumors.

> Glycine is manufactured in the body, but is also commercially

available

> as a dietary supplement.

>

> " These are very preliminary studies, but they are quite interesting, "

> American Association for Cancer Research (AACR) President Waun Ki

Hong,

> MD, tells WebMD. He says that human studies are needed to verify the

> findings, but this may represent an important contribution to the

> research. AACR co-sponsored the annual meeting along with the National

> Cancer Institute and the European Organization for Research and

> Treatment of Cancer.

>

> In the green tea research, Aslamuzzaman Kazi, PhD, and colleagues

found

> that polyphenols reduced the level of Bcl-XL protein in prostate

cancer

> cell lines. Bcl-XL has been shown to protect cancer cells from death

--

> known scientifically as apoptosis. " The higher the concentration [of

> polyphenols] the more apoptosis, " Kazi tells WebMD. " Epidemiological

> studies have shown that tea has anticancer activities. We wanted to

try

> to understand the molecular mechanism of this action. "

>

> Studies in humans have, in fact, been inconclusive regarding the role

of

> tea in preventing or slowing cancers. While some have shown a clear

> protective benefit, others have not. The most recent large study,

> published last March in The New England Journal of Medicine, found

that

> drinking green tea did not lower the risk of developing stomach cancer

> in a group of Japanese subjects.

>

> In the glycine study, researcher Zishan Haroon, MD, PhD, and

colleagues

> at Duke University Medical Center, found high levels of glycine

reduced

> breast tumor growth rates by 15% in rats by blocking the growth of new

> tumor-feeding blood vessels. The special diet also reduced

wound-healing

> by 30%, which, Haroon tells WebMD, explains glycine's effect on

tumors.

> " Tumors and wounds have one very important thing in common -- they

both

> produce new blood vessels through the same mechanism, known as

> angiogenesis, " he says. If you can block one response, you can block

the

> other, he says.

>

>

> Getting well is done one step at a time, day by day, building health

> and well being.

>

> To learn more about the Gettingwell group,

> Subscription and list archives are at:

> Gettingwell

>

>

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Really? That is appalling news.... where can I research that a bit more?

 

Femme

 

 

the desert_rat wrote:

>

> Unfortunately green tea also has a high fluoride content.

> Enough to make me avoid it anyway.

> ron

> ______________________

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Green tea fluoride:

http://www.mercola.com/2000/sept/10/green_tea_fluoride_thyroid.htm

 

If there is a problem with this url just go to www.mercola.com and enter

green tea into the search.

 

ron

_____________

Get the FREE email that has everyone talking at

http://www.mail2world.com

 

<>

>

> Femme

> 11/10/2001 3:24:38 AM

> Gettingwell

> Re: HEALTH: Green Tea - Glycine May Slow Tumor

Growth

>

> Really? That is appalling news.... where can I research that a bit

more?

>

> Femme

>

>

> the desert_rat wrote:

> >

> > Unfortunately green tea also has a high fluoride content.

> > Enough to make me avoid it anyway.

> > ron

> > ______________________

>

>

>

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Hi There!

I have researched this! The fluoride in Green Teas are natural fluorides !

There is a world of difference there! Natural fluorides are NOT harmful in ANY

way! Regards, JoAnn

 

JoAnn Guest

joguest

Friendsforhealthnaturally

http://canceranswer.homestead.com/Goodfoods.html

 

 

-

the desert_rat

Gettingwell

Saturday, November 10, 2001 4:21 AM

Re: Re: HEALTH: Green Tea - Glycine May Slow Tumor

Growth

 

 

Green tea fluoride:

http://www.mercola.com/2000/sept/10/green_tea_fluoride_thyroid.htm

 

If there is a problem with this url just go to www.mercola.com and enter

green tea into the search.

 

ron

_____________

Get the FREE email that has everyone talking at

http://www.mail2world.com

 

<>

>

> Femme

> 11/10/2001 3:24:38 AM

> Gettingwell

> Re: HEALTH: Green Tea - Glycine May Slow Tumor

Growth

>

> Really? That is appalling news.... where can I research that a bit

more?

>

> Femme

>

>

> the desert_rat wrote:

> >

> > Unfortunately green tea also has a high fluoride content.

> > Enough to make me avoid it anyway.

> > ron

> > ______________________

>

>

>

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