LEF: New model of cancer development proposed

[Guest guest]

June 2, 2009

New model of cancer development proposed

 

In an article scheduled to appear in the Annals of Epidemiology,

epidemiologist Cedric Garland, DrPH and his associates at the University

of California San Diego's Moores Cancer Center propose that cancer,

rather than commencing with genetic mutations, is initially caused by a

reduction in the of ability of cells to stick together.

 

Research has shown that inadequate vitamin D can result in a loss of

stickiness between cells as well as a loss of differentiation, which

causes cells to revert to a stem cell-like state. Additionally,

extracellular calcium ions are necessary for intercellular adherence.

 

" The first event in cancer is loss of communication among cells due to,

among other things, low vitamin D and calcium levels, " explained Dr

Garland, who is a professor of family and preventive medicine at the UC

San Diego School of Medicine " In this new model, we propose that this

loss may play a key role in cancer by disrupting the communication

between cells that is essential to healthy cell turnover, allowing more

aggressive cancer cells to take over. "

 

Continue Reading:

http://www.lef.org/newsletter/2009/0602_New-Model-of-Cancer-Development-Proposed\

..htm?source=eNewsLetter2009Wk24-1 & key=Article & l=0

[Guest guest]

A few years ago the local papers [ Brooklyn, NY] wrote about a doctor at Long Island College Hospital who said her study showed that cigarette smoking caused cells, that were rectangular and arranged together, to start returning to a round shape and pull apart as they lost their corners.

Mariel--- On Tue, 6/2/09, robert-blau <robert-blau wrote:

robert-blau <robert-blau LEF: New model of cancer development proposed , SymphonicHealth , oleander soup , cancercure , cancercure2 , cancercured , cancer_alternatives , cancervictory Cc: dstone, nkrugl2Date: Tuesday, June 2, 2009, 3:45 AM

 

 

June 2, 2009New model of cancer development proposedIn an article scheduled to appear in the Annals of Epidemiology,epidemiologist Cedric Garland, DrPH and his associates at the Universityof California San Diego's Moores Cancer Center propose that cancer,rather than commencing with genetic mutations, is initially caused by areduction in the of ability of cells to stick together.Research has shown that inadequate vitamin D can result in a loss ofstickiness between cells as well as a loss of differentiation, whichcauses cells to revert to a stem cell-like state. Additionally,extracellular calcium ions are necessary for intercellular adherence. "The first event in cancer is loss of communication among cells due to,among other things, low vitamin D and calcium levels," explained DrGarland, who is a professor of family and preventive medicine at the UCSan Diego School of Medicine "In

this new model, we propose that thisloss may play a key role in cancer by disrupting the communicationbetween cells that is essential to healthy cell turnover, allowing moreaggressive cancer cells to take over." Continue Reading:http://www.lef. org/newsletter/ 2009/0602_ New-Model- of-Cancer- Development- Proposed. htm?source= eNewsLetter2009W k24-1 & key= Article & l= 0