Guest guest Posted December 21, 2007 Report Share Posted December 21, 2007 [lef.org] Health Concern Diabetes Before insulin, botanical medicines were used to treat diabetes. They are remarkably safe and effective. However, because many botanical medicines function similarly to insulin, people taking oral diabetes medications or insulin should use caution to avoid hypoglycemia. Botanical medicines should be integrated into a regimen of adequate exercise, healthy eating, nutritional supplements, and medical support. Coffee berry contains some well-studied phytochemicals such as chlorogenic acid, caffeic acid, ferulic acid, and quinic acid (Charles-Bernard M et al 2005). Some of coffee berry & rsquo;s most impressive effects can be seen in blood glucose management. Chlorogenic acid and caffeic acid are the two primary nutrients in coffee that benefit individuals with high blood sugar. Glucose-6-phosphatase is an enzyme crucial to the regulation of blood sugar. Since glucose generation from glycogen stored in the liver is often overactive in people with high blood sugar (Basu R et al 2005), reducing the activity of the glucose-6-phosphatase enzyme leads to reduced blood sugar levels, with consequent clinical improvements. Chlorogenic acid has been shown to inhibit the glucose-6-phosphatase enzyme in a dose-dependent manner, resulting in reduced glucose production (Hemmerle H et al 1997). In a trial at the Moscow Modern Medical Center, 75 healthy volunteers were given either 90 mg chlorogenic acid daily or a placebo. Blood glucose levels of the chlorogenic acid group were 15 percent to 20 percent lower than those of the placebo group (Abidoff MT 1999). Chlorogenic acid also has an antagonistic effect on glucose transport, decreasing the intestinal absorption rate of glucose (Johnston KL et al 2003), which may help reduce blood insulin levels and minimize fat storage. http://www.lef.org/protocols/ metabolic_health/diabetes_01.htm Quote Link to comment Share on other sites More sharing options...
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