NatProductsInsider.com- Omega-3s Inhibit Bone Loss- Sources Cited

[Guest guest]

Ok, so to answer that person's question- I googled " British Journal

Of Nutrition Omega-3s and Bone Loss " and found this article here..

There are probably more sites to investigate from that search, but

this gives the information needed to find that exact issue of the

British Journal of Nutrition.

 

Other comments?

Misty L. Trepke

http://www..com

-----------------

 

 

http://www.naturalproductsinsider.com/hotnews/63h694259.html

 

Posted on: 03/06/2006

LUBBOCK, Texas--Intake of omega-3 fatty polyunsaturated fatty acids

(n-3 PUFAs) slows loss of bone mineral density (BMD) associated with

aging, according to a clinical trial published in the British

Journal of Nutrition (95, 3:462-68, 2006).

 

Researchers from Texas Tech University, Purdue University and

Winthrop-University Hospital killed seven rats at the beginning of

the clinical trial to determine baseline BMD and administerered the

following fat blends to remaining rats (three groups of n=7seven)

for 20 weeks: 167 g safflower oil, rich in omega-6 (n-6) fatty

acids, + 33 g fish oil from Atlantic menhaden (control n-6 + n-3

diet); 200 g safflower oil (n-6 diet, almost devoid of n-3 PUFAs);

and 190 g fish oil + 10?g corn oil (n-3 diet, rich in n-3 PUFAs). At

the end of the treatment period, all test groups had a lower BMD

than at baseline. However, rats fed the n-3 diet had less bone loss

(as measured by BMD) compared with animals fed the n-6 and control n-

6 + n-3 diets. In addition, rats fed the n-3 diet had higher values

for serum insulin-like growth factor-I, parathyroid hormone, 1,25-

(OH)2 vitamin D3 and bone-specific alkaline phosphatase activity

than the control n-6 + n-3 diet group, but lower bone nitrogen oxide

(NO) production and urinary calcium than the n-6 diet group, which

had higher bone prostaglandin E2 production and serum pyridinoline.

The researchers concluded these findings indicate a protective

action of n-3 PUFAs on aging-induced bone loss in gonad-intact

middle-aged male rats through a modulation of local factors and

systemic calcitrophic hormones.