Guest guest Posted February 3, 2005 Report Share Posted February 3, 2005 hi Noel you say you use it without consequence, but how do you know? what tests are you conducting to determine CoQ10 levels, myocardial function, etc? one of the problems is that nobody is tracking the health effects of red rice yeast, because it is being taken without medical supervision what agency would you report side-effects to? where is the database of consumer complaints? the deleterious effects associated with statins or red rice yeast won't happen overnight but remember, if you want to use a statin or red rice yeast to control cholesterol the patient will have to take it forever, just like statins are prescribed, because once you stop, sure enough cholesterol levels will rise again red rice yeast is far from being the natural health food consumed in Chinese medicine or used as a flavoring agent it contains a standardized amount of mixed mevinolinic acid monacolins, and acts to lower cholesterol in exactly the same way as any other statin, by inhibiting the enzyme HMG-CoA reductase - in otherwords red rice yeast extract is a natural compound that is spiked with standardized amounts of drug-like compounds red yeast might not contain as much of the active drug as lipitor, etc., but it is the SAME substance working in EXACTLY the same way its use to lower cholesterol was preceded by the development of the statin drugs, not the other way around, i.e. there is no significant body of empirical evidence to suggest that Chinese herbalists ever used it to lower cholesterol, primarily because hypercholesterolemia wasn't recognized - it was used for digestion primarily i am suggesting that inhibiting HMG-CoA reductase to reduce to some arbitrary parameter like a cholesterol reading is foolish and myopic cholesterol is not "bad" - its a key nutrient that is the base molecule used to manufacture steroid hormones (testosterone, estrogen, progesterone etc.) and provides integrity to the cell membrane when it is elevated in the blood it indicates an inflammatory condition of the arteries cholesterol is being secreted to repair that damage, to restore integrity to the arterial wall - think of it as the chewing gum in the dam about to burst but what is causing the damage? THAT is the question that a doctor who spends 5 minutes with their patient doesn't want to answer because it is a large question that calls into assumption not only their clinical knowledge but also there very basis of their understanding of cardiovascular disease for this i suggest you check out the research of Dr. Gerald Reaven, and his description of "metabolic syndrome x" for more info look here: http://www.toddcaldecott.com/synX.html you may be aware that the makers of the statins recently applied for access to the OTC market with low dose statins, like what has been approved in the UK it was rejected, primarily because regulators weren't sure that people should take even low dose statins without supervision - so where does that leave red rice yeast? currently in limbo, but i am sure that it will be taken off the market eventually, and while i support health freedom i won't won't be crying over this one in the US, as you are aware, there is a fairly liberal set of regulations called Dietary Supplement Health and Education Act (DSHEA), that was designed to protect the use of empirically tested, time-honored natural remedies unfortunately natural health care companies looking to make a quick buck have used it to sell all manner of "natural" compounds, including semi-synthetic nutraceuticals likes red rice yeast in most cases there is very little or NO data on these products, and i for one won't sit around and let people be guinea pigs, at least not without some comment btw, here is what the PDR says about red rice yeast extract: (http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/ red_0329.shtml) "Since the principal bioactive substance in red yeast rice is lovastatin, all of the warnings, precautions and interactions of pharmaceutical lovastatin apply to red yeast rice, as well. The use of red yeast rice for the management of hyperlipidemia must be medically supervised. Those with a past history of liver disease and those who routinely use alcoholic beverages should exercise caution in the use of red yeast rice. Lovastatin and other HMG-CoA reductase inhibitors occasionally cause myopathy. This is manifested as muscle pain or weakness associated with elevated levels of creatine kinase. Rhabdomyolysis with or without acute renal failure secondary to myoglobinuria, has been reported rarely and can occur at any time. Those using red yeast rice should report promptly to their physicians unexplained muscle pain, tenderness or weakness. Bleeding and/or increased INR values have been reported in a few patients taking warfarin concomitantly with lovastatin. Persistant increases (to more than 3 times the upper limit of normal) in serum aminotransferases (transaminases) occurred in 1.9% of adults who received lovastatin for at least one year in some early clinical trials. It is recommended that liver tests be performed before starting red yeast rice, at 6 and 12 weeks after starting its use, and periodically thereafter. Lovastatin has been reported to lower coenzyme Q (CoQ10) levels." > > Thanks Todd . I am grateful for your input. You are right except, Red > Yeast > Rice is a natural Lipitor without all the side effects and I have used > it > quite successfully on many clients. I have see many people with high > Cholesterol turned away from their Doctors because of a fatty liver; > and the > combination of the two "L-Carnitine & Red Yeast Rice" have worked > wonders. > You are right about the Co Q 10 Depletion but you shouldn't have to > worry > unless you are a Vegetarian. This is usually not the case in a fatty > liver > but I should have mentioned it. Caldecott todd www.toddcaldecott.com "For a successful technology, reality must take precedence over public relations, for Nature cannot be fooled." -Richard P. Feynman Quote Link to comment Share on other sites More sharing options...
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