Hindu Mad Cow Theory Originator's Contact Info

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If anyone has any relevant info to share with Alan Colchester re: his 'Theory,' please contact him.

 

Professor of Clinical Neuroscience and Medical Image Computing

Email:

a.colchester (AT) kent (DOT) ac.uk

Location:

Room 104, R&D Centre

Address:

KIMHSUniversity of KentCanterburyKent CT2 7PDUK

Tel:

01227 82 7200

Fax:

01227 82 7205

 

 

 

ALAN COLCHESTER

Qualifications

BA Physiology & Psychology (Oxon), BM BCh (Oxon), PhD, FRCP, MA (Oxon)

NHS positions

Consultant Neurologist, East Kent HospitalsConsultant Neurologist, Guy’s & St.

Thomas’s HospitalsLead Clinician for Neurosciences, East Kent, 2002-2005

University Positions

Professor of Clinical Neuroscience & Medical Image ComputingDirector of Graduate

Studies, KIMHSDirector of Research, KIMHSHead, Neurosciences and Medical Image

Computing group, KIMHS

Brief Personal profile

I am a clinical academic and divide my time between NHS clinical neurology and

University responsibilities. In the 1990s there was major reorganisation of

London teaching hospitals and of NHS tertiary neurology and neurosurgery

provision, with a number of mergers and closures. There was increasing

recognition of the need to improve services and academic centres outside

London. In 1996 I moved my research laboratory to the University of Kent and

contributed to the development of the Kent Institute of Medicine and Health

Sciences (KIMHS). I have also led the substantial expansion of clinical

neurosciences in East Kent, with the establishment of the East Kent

Neuroscience Unit at the Kent and Canterbury Hospital and several new posts in

neurology (including consultant, clinical academic, specialist registrar, SHO,

nursing, therapy and rehabilitation appointments). I continue my specialist

neurology commitments at Guy’s and St. Thomas’s Hospitals in London, and run a

neurovascular

clinic and multi-disciplinary neurovascular meeting which make an important

contribution to regional services.

I am Chair of the international management Board of the Medical Image Computing

and Computer Assisted Intervention (MICCAI) conference series which has become

established as the leading conference in the field and I am President of the

MICCAI Society. I am a Patron of the Human BSE Foundation.

Research Interests (numbers in brackets refer to selected publications below)

Neurosciences

Transmissable Spongiform Encephalopathies: diagnosis of CJD, and discrimination

between different types of CJD, using MRI[4;5;8;11;22], [QAMRIC Project];

origin of BSE[3;9]; risks of TSE transmission[2] [bSE Inquiry]; improvement of

care of patients with vCJD and other young dementias.Stroke prevention,

particularly carotid endarterectomy and angioplasty[16;18]. Brain morphology

and morphometry: folding pattern of the cerebral cortex[15]; changes in volume

of critical brain structures in amnesias[6;13;14]; measurement of MS and other

lesions on MRI[20;21]

Medical Image Computing[19]; [bIOMORPH Project]

Segmentation: data-driven segmentation of novel objects[10]; brain structures;

histology images Co-registration: MRI and post-mortem pathology images

correlated in individual patients[1;7;12] [QAMRIC Project]; methods for

discontinuous non-rigid co-registration[12;23]; Quantification of

abnormalities; methods for analysis of abnormal intensities and

shapes[4;11]Correction of errors due to low resolution (partial volume effect)

in functional images [PVEOut project]

Clinical Interests

Neurovascular disease, stroke prevention and carotid interventions (specialist

clinic, Guy’s Hospital; multi-disciplinary meeting, St. Thomas’s Hospital) CJD,

young dementias, and memory disordersMultiple sclerosisClinical neuroimaging(17)

General neurology (clinic, William Harvey Hospital)

Professional Affiliations and Honours

Chairman, International Management Board for Medical Image Computing and

Computer Assisted Intervention (MICCAI), 1999 – President, MICCAI Society, 2004

- Fellow of the Royal College of Physicians; Fellow of the Royal Society of

Medicine Member of Association of British Neurologists; British Medical

Association; British Pattern Recognition AssociationPatron, Human BSE

FoundationCited in Distinguished People of Today, Who’s Who in the World

Selected Publications

Bardinet,E., Colchester, A. C. F., Roche, A., Zhu, Y., Ourselin, S., Nailon, W.,

Hojjatoleslami, S. A., Ironside, J. W., Al-Sarraj, S., Ayache, N., and Wardlaw,

J. (2001) Registration of reconstructed post-mortem optical data with MR scans

of the same patient. Medical Image Computing and Computer-Assisted Intervention

Conference Proceedings: Niessen, W. J. and Viergever, M. A. (Eds.).

Colchester,A.C.F. and Brown, P. J. (1999) Cluster of vCJD cases in Kent and its

importance. Lancet 353: 1357-1357. Colchester,A.C.F. and Colchester, N. T. H.

(2005) The origin of bovine spongiform encephalopathy. Lancet 366: 856-861.

Colchester,A.C.F., Hojjat, S. A., Zerr, I., and Collie, D. A. (2004) MR

intensity analysis to discriminate variant, sporadic CJD, and non-CJD dementia

patients. Journal of Neurology,Neurosurgery and Psychiatry 75: 41.

Colchester,A.C.F., Hojjatoleslami, S. A., Will, R. G., and Collie, D. A. (2002)

Quantitative validation of MR intensity of abnormalities in variant CJD. Journal

of Neurology Neurosurgery and Psychiatry 73: 216. Colchester,A.C.F., Kingsley,

D., Lasserson, D., Kendall, B. E., Bello, F., Rush, C., Stevens, T., Goodman,

G., Heilpern, G., Stanhope, N., and Kopelman, M. D. (2001) Structural MRI

volumetric analysis in patients with organic amnesia, 1: methods and

comparative findings across diagnostic groups. Journal of

Neurology,Neurosurgery and Psychiatry 71: 13-22. Colchester,A.C.F., Ourselin,

S., Zhu, Y., Bardinet, E., He, Y., Roche, A., Al-Sarraj, S., Nailon, W.,

Ironside, J. W., and Ayache, N. (2000) 3-D reconstruction of macroscopic

optical brain slice images pp 95-105. In: Delp, S., DiGioia, A. M., and

Jaramaz, B. (Eds.). Medical Image Computing and Computer-Assisted Intervention

Conference Proceedings. Collie,D.A., Sellar, R. J., Zeidler, M., Colchester, A.

C. F., Knight, R., and Will, R. G. (2001) MRI of Creutzfeldt-Jakob disease:

imaging features and recommended MRI protocol. Clinical Radiology 56: 726-739.

Ford,J.F., Colchester, N. T. H., and Colchester, A. C. F. (2005) New data on UK

imports of mammalian material from the Far East: a potential route of TSE

transmission. Journal of Neurology Neurosurgery and Psychiatry 76: 45. Fu,G.,

Hojjat, S. A., and Colchester, A. C. F. (2004) Integrating watersheds and

critical point analysis for object detection in discrete 2D images. Medical

Image Analysis 8: 177-185. Hojjat,S.A., Collie, D. A., and Colchester, A. C. F.

(2002) The putamen intensity gradient in CJD diagnosis. Medical Image Computing

and Computer-Assisted Intervention Conference Proceedings: Dohi, T and Kikinis,

R. (Eds.). Kenwright,C., Bardinet, E., Hojjat, S. A., Malandain, G., Ayache, N.,

and Colchester, A. C. F. (2003) 2-D to 3-D refinement of post-mortem optical and

MRI co-registration. Medical Image Image Computing and Computer-Assisted

Intervention Conference Proceedings: Ellis, R. E. and Peters, T. M. (Eds.).

Kopelman,M.D., Lasserson, D., Kingsley, D., Bello, F., Rush, C., Stanhope, N.,

Stevens, T., Goodman, G., Heilpern, G., Kendall, B. E., and Colchester, A. C.

F. (2001) Structural MRI volumetric analysis in patients with organic amnesia,

2: correlations with anterograde memory and executive tests in 40 patients.

Journal of Neurology,Neurosurgery and Psychiatry 71: 23-28. Kopelman,M.D.,

Lasserson, D., Kingsley, D. R., Bello, F., Rush, C., Stanhope, N., Stevens, T.

G., Goodman, G, Buckman, J. R., Heipern, G., Kendall, B. E., and Colchester, A.

C. F. (2003) Retrograde amnesia and the volume of critical brain structures.

Hippocampus 13: 879-891. Lohmann,G., von Cramon, D. Y., and Colchester, A. C.

F. (2005) A construction of an averaged representation of human cortical gyri

using non-linear principal component analysis. Medical Image Image Computing

and Computer-Assisted Intervention Conference Proceedings: Gerig, G. and

Duncan, J. (Eds.). Padayachee,T.S., Arnold, J. A., Thomas, N., Aukett, M.,

Colchester, A. C. F., and Taylor, P. R. (2002) Correlation of intra-operative

duplex findings during carotid endarterectomy with neurological events and

recurrent stenosis at one year. European Journal of Vascular and Endovascular

Surgery 24: 435-439. Samuel,M. and Colchester, A. C. F. (2005) Structural and

functional magnetic resonance imaging in neurodegenerative diseases, 253-289.

In: Beal, M. F., Lang, A. E., and Ludolph, A. E. (Eds.). Neurodegenerative

Diseases Cambridge: Cambridge University Press. Sandison,A.J.P., Wood, C. H.,

Padayachee, T. S., Colchester, A. C. F., and Taylor, P. R. (2000) Cost

effective carotid endarterectomy. British Journal of Surgery 87: 323-327.

Taylor,C.J. and Colchester, A. C. F. (1999) Medical Image Computing and

Computer Assisted Intervention Conference Proceedings, 1240. Van Leemput,K.,

Maes, F., Bello, F., Vandermeulen, D., Colchester, A. C. F., and Suetens, P.

(1999) Automated segmentation of MS lesions from multi-channel MR images pp

11-21. In: Taylor, C. J. and Colchester, A. C. F. (Eds.). Medical Image

Computing and Computer-Assisted Intervention Conference Proceedings. Van

Leemput,K., Maes, F., Vandermeulen, D., Colchester, A. C. F., and Suetens, P.

(2001) Automated Segmentation of Multiple Sclerosis Lesions by Model Outlier

Detection. IEEE Transactions on Medical Imaging 20: 677-688. Zeidler,M.,

Sellar, R. J., Collie, D. A., Knight, R., Stewart, G. E., Macleod, M-A.,

Ironside, J. W., Cousens, S. N., Colchester, A. C. F., Hadley, D. M., and Will,

R. G. (2000) The pulvinar sign on magnetic resonance imaging in variant

Creutzfeldt-Jakob disease. Lancet 355: 1412-1418. Zhu,Y. and Colchester, A. C.

F. (2004) Plane curve matching under affine transformations. IEE Proceedings on

Vision, Image and Signal Processing 151: 9-19.

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