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Blood-thinning drug could transform stroke treatment

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A new blood-thinning drug could end the use of rat poison as a primary medical

treatment to prevent stroke, it was claimed today.

 

For half a century, thousands of patients at risk of stroke have been given

warfarin to prevent blood clotting. But treatment with the drug, commonly used

to kill vermin, is risky.

 

Doses have to be carefully watched and adjusted to prevent excessive bleeding

from cuts or stomach ulcers, requiring frequent clinic visits. Warfarin can also

interact badly with other drugs and certain foods.

 

The new drug, Pradaxa, works in a different way and is far safer. Patients

taking the pill twice a day do not have to be constantly checked for signs of

overdosing, and can eat what they like.

 

Results from a major trial showed that Pradaxa was 34 per cent better at

reducing the risk of stroke and blood clots in at-risk patients than

well-controlled warfarin. More than 18,000 patients from 44 countries took part

in the three-year RE-LY (randomised evaluation of long term anticoagulant

therapy) trial, the largest of its kind ever conducted.

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Then, of course, you could just change to a more healthy diet,

but that would be way too easy.

 

 

Mon Aug 31, 2009 7:38 pm (PDT)

 

Monday, 31 August 2009

 

A new blood-thinning drug could end the use of rat poison as a primary

medical treatment to prevent stroke, it was claimed today.

 

For half a century, thousands of patients at risk of stroke have been

given warfarin to prevent blood clotting. But treatment with the drug,

commonly used to kill vermin, is risky.

 

Doses have to be carefully watched and adjusted to prevent excessive

bleeding from cuts or stomach ulcers, requiring frequent clinic visits.

Warfarin can also interact badly with other drugs and certain foods.

 

The new drug, Pradaxa, works in a different way and is far safer.

Patients taking the pill twice a day do not have to be constantly

checked for signs of overdosing, and can eat what they like.

 

Results from a major trial showed that Pradaxa was 34 per cent better at

reducing the risk of stroke and blood clots in at-risk patients than

well-controlled warfarin. More than 18,000 patients from 44 countries

took part in the three-year RE-LY (randomised evaluation of long term

anticoagulant therapy) trial, the largest of its kind ever conducted.

 

Participants had an average age of 71 and all suffered from atrial

fibrillation, a heart rhythm disorder that greatly increases the risk of

stroke. They were randomly assigned to treatment either with Pradaxa or

warfarin.

 

The findings were published online in the New England Journal of Medicine.

 

Professor Stuart Connolly, one of the leading investigators from

McMaster University in Hamilton, Canada, said: " We now have an oral

treatment which offers superior protection from stroke with less

bleeding and without the need for routine monitoring. "

 

At present the drug is only licensed in the UK for the treatment of

orthopaedic patients at risk of clotting after surgery. An application

for permission to use it for the prevention of stroke is pending.

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Maybe you can explain this for me????.I do not understand why anybody would

even think about taking a drug for blood-thinning when Systemic Enzymes do the

job so well and there are no side-effects at all. I am talking about Systemic

Enzymes - not digestive enzymes.

 

Systemic vs. Digestive Enzymes: What's the Difference?

Systemic enzymes are usually only the proteolytic (protein lysing) enzymes; they

are either entericly coated or cultured to be acid and heat resistant. These

enzymes are much more expensive to produce than those used for digestion even

when they have the same names. Systemic enzymes are engineered to survive

stomach acid and get into the small intestine where they are to be absorbed into

the blood stream. Digestive enzymes, on the other hand, have a broad range of

enzymes for protein digestion, as well as for the digestion of fiber,

(cellulase) carbohydrates (amylase) and fats (lipase). The products actions are

limited to the GI tract and these enzymes are not generally of high quality,

enteric coating or protection from the acidic stomach juices. They do not

survive well nor are they present in sufficient quantity after being used for

digestion to be absorbed into the blood stream.

 

Everything You Learned About Enzymes Was Wrong

 

First let talk about what an enzyme is – an enzyme is a large protein molecule

that cleaves, cuts or eats specific pre-designated things (think of Pac Man with

shark-like teeth). Depending on the programming of the " teeth " , the enzymes

fit over certain substances in a lock and key fashion, cutting through one

specific type of thing, a particular type protein let's say, yet leaving

undisturbed protein of a similar but slightly different type. Enzymes are

essential as " bio catalysts " , in other words they speed the action of chemical

reactions. Without enzymes involved in every cellular event in our bodies, the

chemical reactions within us would be so slow as to make life as we know it

impossible. There are some 3000+ enzymes in the human body, most of them of the

proteolytic type. These 3000+ enzymes create between 7000 to 25000 different

enzyme reactions. The 3000 enzymes themselves are created as a result of either

our own enzyme production (which is finite in nature), or created from ingesting

enzymes from our live or uncooked food. The first thing the proteolytic enzymes

do is to create what is known as the enzyme cascade. Most of the enzymes active

in the reactions that occur body- wide are proteolytic in nature; that is, they

are concerned with cleaving a type of specific protein or another (we have

literally hundreds of different types and arrangements of proteins in our

bodies). So the vast majority of the 7000 to 25,000 enzymatic reactions that

need to happen within us are proteolytic in nature. Aside from the 25,000

possible reactions of protein eating enzymes science now knows, they have 5

primary functions: Natural Anti-Inflammatory; Anti Fibrosis; Blood Cleansing;

Immune System Modulating; Virus Fighting.; Fat Loss / Energy Releasing By

Dissolving Body Fat. References here.

[url="http://www.enerex.ca/articles/everything_you_learned_about_enzymes_was_wrong.htm"]

 

>

>

> Monday, 31 August 2009

>

> A new blood-thinning drug could end the use of rat poison as a primary medical

treatment to prevent stroke, it was claimed today.

>

>

> For half a century, thousands of patients at risk of stroke have been given

warfarin to prevent blood clotting. But treatment with the drug, commonly used

to kill vermin, is risky.

>

> Doses have to be carefully watched and adjusted to prevent excessive bleeding

from cuts or stomach ulcers, requiring frequent clinic visits. Warfarin can also

interact badly with other drugs and certain foods.

>

> The new drug, Pradaxa, works in a different way and is far safer. Patients

taking the pill twice a day do not have to be constantly checked for signs of

overdosing, and can eat what they like.

>

> Results from a major trial showed that Pradaxa was 34 per cent better at

reducing the risk of stroke and blood clots in at-risk patients than

well-controlled warfarin. More than 18,000 patients from 44 countries took part

in the three-year RE-LY (randomised evaluation of long term anticoagulant

therapy) trial, the largest of its kind ever conducted.

>

> Participants had an average age of 71 and all suffered from atrial

fibrillation, a heart rhythm disorder that greatly increases the risk of stroke.

They were randomly assigned to treatment either with Pradaxa or warfarin.

>

> The findings were published online in the New England Journal of Medicine.

>

> Professor Stuart Connolly, one of the leading investigators from McMaster

University in Hamilton, Canada, said: " We now have an oral treatment which

offers superior protection from stroke with less bleeding and without the need

for routine monitoring. "

>

> At present the drug is only licensed in the UK for the treatment of

orthopaedic patients at risk of clotting after surgery. An application for

permission to use it for the prevention of stroke is pending.

>

>

>

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The reason I posted that article about an allopathic meds on an alternative

health group is because there may well be some members who are on the warfarin

regime, or know someone who is.

My Mother was on warfarin and Digoxin (digitalis) for heart failure and she

lived until her 88th year, maybe without those meds she would have only lived

for 8 score years and 8.

The problem is that when someone gets onto prescribed allopathic drugs, they

fear coming off them - especially in a case of heart failure!

I certainly would never take such drugs - for any reason whatsoever.

 

Kind regards - Ray in England.

 

 

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Diet would not always do the trick, unfortunately. Some diseases actually

make the blood thick and sluggish,for example - ones like Lyme Disease and also

Bartonella come to mind very easily but there are a lot more.

 

And who said that changing to a healthy diet is 'easy'???? Have you even tried

it in this day and age where so much of our food is highly processed? Even

organic food? Did you know for example that organic lemom juice is processed? I

didn't at first; but evidently lemon juice goes bad otherwise. To get the health

benefits of lemon juice you need ot use fresh squeezed lemon juice.

 

blessings

>

> Then, of course, you could just change to a more healthy diet,

> but that would be way too easy.

>

>

>

>

>

> Mon Aug 31, 2009 7:38 pm (PDT)

>

>

>

> Monday, 31 August 2009

>

> A new blood-thinning drug could end the use of rat poison as a primary

> medical treatment to prevent stroke, it was claimed today.

>

> For half a century, thousands of patients at risk of stroke have been

> given warfarin to prevent blood clotting. But treatment with the drug,

> commonly used to kill vermin, is risky.

>

> Doses have to be carefully watched and adjusted to prevent excessive

> bleeding from cuts or stomach ulcers, requiring frequent clinic visits.

> Warfarin can also interact badly with other drugs and certain foods.

>

> The new drug, Pradaxa, works in a different way and is far safer.

> Patients taking the pill twice a day do not have to be constantly

> checked for signs of overdosing, and can eat what they like.

>

> Results from a major trial showed that Pradaxa was 34 per cent better at

> reducing the risk of stroke and blood clots in at-risk patients than

> well-controlled warfarin. More than 18,000 patients from 44 countries

> took part in the three-year RE-LY (randomised evaluation of long term

> anticoagulant therapy) trial, the largest of its kind ever conducted.

>

> Participants had an average age of 71 and all suffered from atrial

> fibrillation, a heart rhythm disorder that greatly increases the risk of

> stroke. They were randomly assigned to treatment either with Pradaxa or

> warfarin.

>

> The findings were published online in the New England Journal of Medicine.

>

> Professor Stuart Connolly, one of the leading investigators from

> McMaster University in Hamilton, Canada, said: " We now have an oral

> treatment which offers superior protection from stroke with less

> bleeding and without the need for routine monitoring. "

>

> At present the drug is only licensed in the UK for the treatment of

> orthopaedic patients at risk of clotting after surgery. An application

> for permission to use it for the prevention of stroke is pending.

>

>

 

 

Has anyone experienced any side effects after taking Pradaxa? What should you do if your teeth start bleeding? I will be going to see a dentists soon and am worried of my teeth bleeding.

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Guest Guest

Hi,

 

Has anyone experienced side effects after taking Pradaxa? What should you do if your teeth start bleeding? I will be going to see a dentists soon and am worried of my teeth bleeding.

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Guest Guest

The generic name of Pradaxa is Dabigatran. It is prescribed to patients who are at high risk for strokes. It helps prevent atrial fibrillation. There are some side effects when taking Pradaxa, but these mainly occur in elderly patients.

 

Some of the rare but serious side effects include include bilirubin and hepatic dysfunction, myocardial infarction, anaphylactic shock and anaphylactic reaction, and elevations in liver transaminases. These are very rare occurences. Minor side effects are more common, these include acid reflux and indigestion.

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