Our internal universe ends when we end ego:


http://bhagavatam.net/12/4/en1

Chapter 4: The Four Categories of Universal Annihilation

SB 12.4.38: In this way the progress of time is described in terms of the four kinds of annihilation -- continuous, occasional, elemental and final [atyantika]

SB 12.4.34: My dear Parikshit, when the illusory false ego that binds the soul has been cut off with the sword of discriminating knowledge and one has developed realization of Lord Acyuta, the Supreme Soul, this is called the atyantika, or ultimate, annihilation of material existence

SB 12.4.40: For a person who is suffering in the fire of countless miseries and who desires to cross the insurmountable ocean of material existence, there is no suitable boat except that of cultivating devotion to the transcendental taste for the narrations of the Supreme Personality of Godhead's pastimes

The macro and the micro viewpoints are presented. Often we become enamored at the macrocosmic and lose sight of how it all plays out within us individually.